Biomguide
Biomguide
SETTING  UP  YOUR  L
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This   guide  explains   the  use  of   the   biom  document   class   le  for   L
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X2 .   This   document   class   allows   authors   to
prepare  manuscripts  for  submission  to  Biometrics,  the  nal  appearance  and  layout  of  which  is  that  of  a  typeset  article
appearing in  the journal. Authors should use the document class to prepare a postscript or PDF version of their  papers
for  submission  for  consideration  by  the  editors,  as  the  Biometrics  Central  Editorial  Oce  and  Blackwell  Publishing  do
not  have  access  to  L
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X2  software  and  therefore  cannot  process  L
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X2  source  les  directly.
The  biom  class  le  is  based  on  the  mn  style  le,   which  in  turn  is  based  on  article  style  as  discussed  in  Lamports
L
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X  manual  (L
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X:  A  Document  Preparation  System,  Addison  Wesley,  Reading,  Mass.,  1994.  ISBN  0201529831).
Commands  that  dier  from  the  standard  L
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X  interface,  or  that  are  provided  in  addition  to  the  standard  interface,
are  explained  in  this  guide.   This  guide  is  not  a  substitute  for  a  comprehensive  L
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X  manual   itself.   Authors  planning
to  prepare  their  papers  using  L
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X  are  advised  to  use  biom.cls  as  early  as  possible  in  the  creation  of  their  les  so  as
to  avoid  possible  conicts  that  may  emerge  upon  switching  to  the  document  class  later.
Distributed  with  the   biom.cls  le   are   the   L
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X  source   for   three   specimen  (example)   articles,   biomsample.tex
and  biomsample  bib.tex,   whose  content  is  nonsensical   but  which  exhibit  several   features  of   the  document  class;   and
biomsample2.tex,   which  uses  the  document  class  to  typeset  an  actual,   previously-published  Biometrics  article.   Also
included  is  the le  biomtemplate.tex,  which authors may  use as  a template  for creating the L
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X source for their  own
manuscripts.  The  le  biomtemplate.tex  is  heavily  documented  with  comments  that  address  many  issues  of  convention
and  style.  The  distribution  also  includes  a  custom  package,   endrotfloat.sty,  which  is  used  by  biom.cls  when  tables
presented in landscape model are included in a document (see Section 2.2). Additional L
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X packages may be required to
implement some features discussed in this guide. These packages are noted in the relevant sections of this guide. If these
packages are not already incorporated in your local distribution of L
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X  they may be obtained from the Comprehensive
T
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X  Archive   Network  (CTAN)   at   http://www.ctan.org/.   Finally,   the   distribution  also  includes   additional   les   of
interest  to  users  of  BiBTeX,  discussed  in  Section  4.7.3.
1.   The  BIOM  Document  Class
The  use  of  L
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X  document  classes  allows  a  simple  change  of  class  to  transform  the  appearance  of  your  document.  The
biom  class  le  preserves  the  standard  L
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X  interface  such  that  any  document  that  can  be  produced  using  the  standard
L
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X  article  class  can  also  be  produced  with  the  biom  class  le.  However,  the  measure  (or  width  of  text)  is  broader
than  the  default  for  article,  and  even  narrower  than  for  the  A4  style.
It  is  likely  that,  should  your  article  be  accepted  for  publication,  the  nal  formatting  of  will  change  slightly  from  that
produced  when  you  yourself  process  it  using  biom.cls.  For  this  reason,  we  ask  that  you  ignore  details  such  as  slightly
long  lines,   page  stretching,   or  gures  falling  out  of  synchronization,   because  these  details  can  be  dealt  with  at  a  later
stage  by  the  publisher.   Please  also  use  symbolic  references  (\ref)  in  order  to  protect  against  late  changes  of   order  of
sections,  equations,  etc.
All   papers  submitted  to  Biometrics  should  be  prepared  using  the  referee  option  in  the  documentclass
command, as discussed in Section 2. This option produces a version of the manuscript suitable for review by editors and
referees, obeying the journal convention of 1 inch margins, 25 lines per page, and 12 point type. Submitted manuscripts
prepared  without  invoking  the  referee  option  will  be  returned  to  the  authors  for  reformatting.
2   SETTING  UP  YOUR  L
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2.   Using  the  BIOM  Class  File
If   the  le  biom.cls  is  not  already  in  the  appropriate  system  directory  for  L
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X  les,   either  arrange  for  it  to  be  put
there or copy it to your working directory. The biom document class is implemented as a complete class, not  a document
style  option.  In  order  to  use  the  Biometrics  document  class,  replace  article  by  biom  in  the  \documentclass  command
at  the  beginning  of  your  document;  that  is,
\documentclass{article}
is  replaced  by
\documentclass{biom}
In  general,  the  following  standard  document  style  options  should  not   be  used  with  the  biom  class  le:
(1)   10pt,  11pt,  12pt    unavailable;
(2)   twoside  (no  associated  style  le)    twoside  is  the  default;
(3)   fleqn,  leqno,  titlepage    should  not  be  used  (fleqn  is  already  incorporated  into  the  Biometrics  style);
(4)   twocolumn    is  not  necessary  as  it  is  the  default  style.
The  biom  class  le  has  been  designed  to  operate  with  the  standard  version  of  lfonts.tex  that  is  distributed  as  part
of L
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X. Attempt to typeset the specimen or template les mentioned above. If you encounter font problems, you might
investigate  whether  a  non-standard  version  of  lfonts.tex  has  been  installed  in  your  system.
Authors  using  L
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X  wishing  to  create  PDF  les  with  smooth  fonts  are  advised  to  read  Adobe  FaxYI   Document
Number   131303  by  Kendall   Whitehouse.   Type  1  PostScript   versions   of   the  Computer   Modern  fonts   are  now  freely
available  and  are  normally  installed  with  new  T
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X/L
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X  software.
2.1   Additional   Document  Style  Options
The  following  additional  style  options  are  available  with  the  biom  class  le:
onecolumn    to  be  used  only  when  two-column  output  is  unable  to  accommodate  long  equations;
doublespacing    this  will  double-space  your  article  by  setting  \baselinestretch  to  2.
referee    this  enables  the  production  of   a  version  of   the  manuscript  suitable  for  review  by  editors  and  referees.   All
papers  submitted  for  publication  should  be  prepared  using  this  option.
galley    no  running  heads,  no  attempt  to  align  the  bottom  of  columns.
useAMS    this  enables  the  production  of  upright  Greek  characters  ,    and  .
usedcolumn    this  uses  the  package  le  dcolumn.sty  to  dene  two  new  types  of  column  alignment  for  use  in  tables.
usenatbib    this  uses  Patrick  Dalys  natbib  package  for  cross-referencing.
usegraphicx    this   enables   the  use  of   the  graphicx  package  for   inclusion  of   gures.   Note  that   the  standard  L
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graphics  package  graphicx.sty  is  required  in  order  to  use  the  usegraphicx  option.
Please  place  any  additional   command  denitions  at  the  very  start  of   the  L
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X  le,   before  the  \begin{document}.
For  example,   user-dened  \def  and  \newcommand  commands  that  dene  macros  for  technical   expressions  used  in  the
manuscript  should  be  placed  here.   Other  author-dened  macros  should  be  kept  to  a  minimum.   Please  do  not  include
macros that are not used in the document. Also, please do not customize the Biometrics macros or class le, or redene
macros  that  are  already  in  the  class  le,  and  please  do  not  include  additional  denitions  unless  they  are  actually  used
in  the  paper.
2.2   Landscaping  Pages
If   a  table  is  too  wide  to  t  the  standard  measure,   it  may  be  turned,   with  its  caption,   90  degrees.   Landscape  tables
cannot be produced directly using the  biom class le because T
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X itself cannot turn the page, and not all device drivers
provide  such  a  facility.  The  following  procedure  can  be  used  to  produce  such  pages.
(1)   Use  the  package  rotating  in  your  document  (see  the  specimen  and  template  les  for  examples)  and  change  the
coding  from
\begin{table}...\end{table}
to
\begin{sidewaystable}...\end{sidewaystable}
environments  in  your  document  to  turn  your  table  on  the  appropriate  page  of   your  document.   For  instance,   the
SETTING  UP  YOUR  L
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following  code  prints  a  page  with  the  running  head,   a  message  half   way  down  and  the  table  number  towards  the
bottom.
\begin{sidewaystable}
\caption{Landscape   table   to   go   here.}
\label{landtab}
\end{sidewaystable}
3.   Additional   Facilities
In  addition  to  all  the  standard  L
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X  design  elements,  the  biom  class  le  includes  a  number  of  custom  features.  These
are  noted  throughout  this  guide.   Once  you  have  used  these  additional   biom.cls  facilities  in  your  document,   do  not
process  it  with  a  standard  L
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X  class  le.
3.1   Titles  and  Authors  Name(s)
The title of the article and the authors name and aliation (or authors names and aliations) are used at the beginning
of  the  article  for  the  main  title.   At  the  beginning  of  your  article,   the  title  should  be  generated  in  the  usual   way  using
the  \maketitle command. See the specimen les and the template le for demonstration, and see the following sections
for  more  details.
3.2   Running  Headline
A  shortened  version  of  the  title  of  the  manuscript  will  be  used  as  a  running  headline  at  the  top  of  every  odd-numbered
page.   Although  the  full   manuscript  title  can  run  to  several   lines  of   text,   the  running  headline  must  be  a  single  line.
Moreover, new line commands (e.g. \\) are not acceptable in a running headline. To enable you to specify a short running
head, the standard \title command has been extended to take an optional argument to be used as the running headline.
The  running  headlines  can  be  produced  using  the  following  code:
\title[This   is   a   Shortened   Article   Title]
{This   is   an   Example   of   a   Rather   Long   and   Drawn   Out   Full-Length
Article   Title}
For  even-numbered  pages,   if   you  include  the  \pubyear  and  \artmonth  commands,   the  running  head  will   show  the
month  and  year  you  specify;  for  example:
\pubyear{2008}
\artmonth{December}
will  produce  Biometrics,  December  2008  on  each  even-numbered  page.
The   \pagestyle  and  \thispagestyle  commands   should  not   be   used.   Similarly,   the   commands   \markright  and
\markboth  should  not  be  necessary.
3.3   Author  Names  and  Aliations
The   \author,   \email,   and  \emailx  commands   may  be   used  in  combination  to  produce   author/aliation  displays
consistent  with  the  Biometrics  style  conventions.   The  \email  command  produces  the  email   address  specied  with  an
asterisk  *  superscript,   so  that   it   may  be  footnoted  in  the  author   list.   The  \emailx  command  produces   the  email
address  with  no  such  superscript.
The  following  are  examples  of  how  to  create  author  and  aliation  displays  consistent  with  the  journal   conventions
for  several  dierent  scenarios.  These  examples  appear  in  the  template  le  and  may  be  customized  for  your  document.
(1)   For a single authored manuscript. Use \emailx so that no asterisk footnoting for the email address will be produced.
\author{John   Author\emailx{email@address.edu}   \\
Department   of   Statistics,   University   of   Warwick,   Coventry   CV4   7AL,   U.K.}
(2)   For two authors from the same institution, with both emails, use  \email to produce the asterisk footnoting for each
email  address.
4   SETTING  UP  YOUR  L
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\author{John   Author$^{*}$\email{author@address.edu}   and
Kathy   Authoress$^{**}$\email{email2@address.edu}   \\
Department   of   Statistics,   University   of   Warwick,   Coventry   CV4   7AL,   U.K.}
(3)   For  exactly  two  authors  from  dierent  institutions,  both  with  email  addresses,  use  \emailx  here  so  that  no  asterisk
footnoting  for  the  email  addresses  is  produced.
\author
{John   Author\emailx{author@address.edu}   \\
Department   of   Statistics,   University   of   Warwick,   Coventry   CV4   7AL,   U.K.
\and
Kathy   Author\emailx{anotherauthor@address.edu}   \\
Department   of   Biostatistics,   University   of   North   Carolina   at   Chapel   Hill,
Chapel   Hill,   North   Carolina,   U.S.A.}
(4)   For three or more authors from same institution with all emails displayed and footnoted using asterisks, use  \email
as  follows
\author{John   Author$^*$\email{author@address.edu},
Jane   Author$^{**}$\email{jane@address.edu},   and
Dick   Author$^{***}$\email{dick@address.edu}   \\
Department   of   Statistics,   University   of   Warwick,   Coventry   CV4   7AL,   U.K}
(5)   For  three  or  more  authors  from  same  institution  with  one  corresponding  email  displayed,  use  \email.
\author{John   Author$^*$\email{author@address.edu},
Jane   Author,   and   Dick   Author   \\
Department   of   Statistics,   University   of   Warwick,   Coventry   CV4   7AL,   U.K}
(6)   For  three  or  more  authors,   with  at  least  two  dierent  institutions  and  more  than  one  email   displayed,   use  \email
as  follows
\author{John   Author$^{1,*}$\email{author@address.edu},
Kathy   Author$^{2,**}$\email{anotherauthor@address.edu},   and
Wilma   Flinstone$^{3,***}$\email{wilma@bedrock.edu}   \\
$^{1}$Department   of   Statistics,   University   of   Warwick,   Coventry   CV4   7AL,   U.K   \\
$^{2}$Department   of   Biostatistics,   University   of   North   Carolina   at
Chapel   Hill,   Chapel   Hill,   North   Carolina,   U.S.A.   \\
$^{3}$Department   of   Geology,   University   of   Bedrock,   Bedrock,   Kansas,   U.S.A.}
(7)   For  three  or  more  authors  with  at  least  two  dierent  institutions  and  only  one  email  displayed,  use  \email.
\author{John   Author$^{1,*}$\email{author@address.edu},
Wilma   Flinstone$^{2}$,   and   Barney   Rubble$^{2}$   \\
$^{1}$Department   of   Statistics,   University   of   Warwick,   Coventry   CV4   7AL,   U.K   \\
$^{2}$Department   of   Geology,   University   of   Bedrock,   Bedrock,   Kansas,   U.S.A.}
Note that, in all of these examples, you must create the footnotes manually. If your conguration of authors, aliations,
and  email  addresses  is  not  demonstrated  explicitly  above,  please  review  recent  issues  of  Biometrics  to  nd  an  instance
of  your  conguration,   and,   using  the  examples  above  to  assist  you,   make  sure  that  your  display  is  consistent  with  the
convention  shown  in  the  journal  for  your  conguration.
3.4   Abstracts  and  Key  Words
The  abstract  should  be  enclosed  within  an  abstract  environment,  followed  immediately  by  the  key  words,  presented  in
alphabetical  order,  enclosed  in  a  keywords  environment.  For  example:
\begin{abstract}
This   guide   is   for   authors   who   are   preparing   papers   for
\textit{Biometrics},   published   by   the   International   Biometric
Society},   using   the   \LaTeXe\   document   preparation   system   and   the   {\tt
SETTING  UP  YOUR  L
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biom}   class   file.
\end{abstract}
\begin{keywords}
\verb"biom.cls"\;   Class   files;   \LaTeXe\,;   Sample   text;   User   guide.
\end{keywords}
\maketitle
\section{Introduction}
The  headings  Summary:  and  Key  words:  are  created  automatically,   and  the  key  words  are  followed  by  vertical
space.  For  example,
\begin{abstract}
:
\end{abstract}
\begin{keywords}
:
\end{keywords}
\maketitle
\section{Introduction}
4.   Some  Guidelines  for  Using  Standard  Facilities
The  following  notes  may  help  you  achieve  the  best  eects  with  the  biom  class  le.
4.1   Sections
L
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\section
\subsection
\subsubsection
\paragraph
However, the use of \subsubsection and \paragraph headings is generally discouraged. In the \section and \subsection
headings,  the  rst  letter  of  each  major  word  (except  for  articles,  conjunctions,  etc.)  should  be  capitalized.
Section  numbers   are  automatically  generated  for   section,   subsection,   subsubsection  and  paragraph  headings,   and
headings  are  displayed  in  the  typeface  consistent  with  the  journal  style  for  that  type  of  heading.
4.2   Lists
The  biom  class  le  provides  unnumbered  lists  using  the  description  environment  for  example,
First  unnumbered  item  has  no  label   and  is  indented  from  the  left  margin  if   it  wraps  to  a  second  line,   which  in  this
example  it  denitely  does
Second  unnumbered  item.
Third  unnumbered  item  which  has  no  label
was  produced  by:
\begin{description}
\item   First   unnumbered   item...
\item   Second   unnumbered   item.
\item   Third   unnumbered   item   which   has   no   label
\end{description}
6   SETTING  UP  YOUR  L
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The  biom  class  le  also  provides  bullet/itemize  lists  using  the  itemize  environment  for  example,
   First  unnumbered  item  has  no  label   and  is  indented  from  the  left  margin  if  it  wraps  to  a  second  line,   which  in  this
example  it  denitely  does
   Second  unnumbered  item.
   Third  unnumbered  item  which  has  no  label  and  is  indented  from  the  left  margin.
was  produced  by:
\begin{itemize}
\item   First   unnumbered   item   which   has   no   label   and   is   indented   from   the   left   margin   which   has   no   label.
\item   Second   unnumbered   item.
\item   Third   unnumbered   item   which   has   no   label   and   is   indented   from   the   left   margin.
\end{itemize}
Numbered  lists  is  also  provided  in  biom  class  le  using  the  enumerate  environment  for  example,
(1)   The  attenuated  and  diluted  stellar  radiation.  The  attenuated  and  diluted  stellar  radiation;
(2)   Scattered  radiation,  and
(3)   Reradiation  from  other  grains.
was  produced  by:
\begin{enumerate}
\item   The   attenuated   and   diluted   stellar   radiation.   The   attenuated   and   diluted   stellar   radiation;
\item   Scattered   radiation,   and
\item   Reradiation   from   other   grains.
\end{enumerate}
Note   here   the   the   standard  form  of   the   enumerate  environment   has   been  replaced  by  a  style   consistent   with  the
Biometrics  convention  for  numbered  lists.  The  following  example  shows  how  to  obtain  the  standard  form:
1.   The  attenuated  and  diluted  stellar  radiation;
2.   Scattered  radiation,  and
3.   Reradiation  from  other  grains.
was  produced  by:
\begin{enumerate}
\item[1.]   The   attenuated   and   diluted   stellar   radiation;
\item[2.]   Scattered   radiation,   and
\item[3.]   Reradiation   from   other   grains.
\end{enumerate}
4.3   Figures
The  biom  class  le  will   cope  with  most  positioning  of   your  gures  in  the  nal   version  of   your  manuscript  when  it  is
prepared using the default journal two-column, single-spaced format. You should place gures close to (but usually after)
the  points  in  the  text  where  they  are  rst  referenced.  When  the  referee  option  is  used,  all  gures  will  be  displayed  at
the end of the document, but you should nonetheless place them as for the nal version. Although you are preparing an
article  for  submission  using  the  referee  option,   viewing  your  article  in  the  default,   two-column  format  will   show  you
whether  or  not  your  gures  are  being  placed  correctly.
You  should  not   normally   use   the   optional   positional   qualiers   on  the   figure   environment   that   would  override
these  decisions.  See  http://www.blackwellpublishing.com/bauthor/illustration.asp  for  details  regarding  submis-
sion  guidelines   for   securing  print-quality  of   artwork.   Figure  captions   should  be  below  the  gure  itself,   therefore  the
\caption  command  should  appear  after  the  gure  or  space  left  for  an  illustration.   For  example,   Figure  1  is  produced
using  the  following  commands:
\begin{figure}
\centerline{%
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Figure  1.   An  example  gure  caption.
\includegraphics[width=50mm]{art/biom_621_f1.eps}}
%%   to   include   a   figure,   or   to   leave   a   blank   space
\caption{An   example   figure   caption.}
\label{sample-figure}
\end{figure}
Here,   because   this   document   has   only  one   column,   the   gure   spans   the   entire   width.   However,   when  using  the
document class with the default two-column option, gures created using  \begin{figure}...\end{figure} will appear
in  a  single  column.   In  order  to  create  a  gure  that  spans  across  both  columns,   as  is  often  the  case  in  the  journal,   you
should  instead  use  \begin{figure*}...\end{figure*}.   When  your  document  is  processed  using  the  referee  option,
all  gures  will  appear  across  the  entire  page,  regardless  of  which  environment  was  specied.
Cross-referencing  of   gures,   tables,   and  numbered,   displayed  equations   using  the   \label  and  \ref  commands   is
strongly encouraged. For example, in referencing Figure 1 above, we used For   example,   Figure~\ref{sample-figure}   is
produced   using...
4.4   Tables
The  biom  class  le  will   cope  with  most  positioning  of   your  tables  as  well,   and,   you  should  place  them  as  with  gures
near  where  you  would  like  them  to  appear.   Again,   with  the  referee  option,   they  will   be  moved  automatically  to  the
end  of   the  document.   You  should  not  normally  use  the  optional   positional   qualiers  on  the  table  environment  that
would  override  these  decisions.   Table  captions  should  be  at  the  top,   therefore  the  \caption  command  should  appear
above  the  body  of  the  table.
Commands   to  redene   quantities   such  as   \arraystretch  should  be   omitted  in  general.   For   example,   Table   1  is
produced  using  the  following  commands.  Note  that  \rmn  will  produce  a  roman  character  in  math  mode.  There  are  also
\bld  and  \itl,  which  produce  bold  face  and  text  italic  in  math  mode.
\begin{table}
\caption{Radio-band   beaming   model   parameters.}   \label{symbols}
8   SETTING  UP  YOUR  L
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Table  1
Radio-band  beaming  model   parameters.
Class   1   2      G   f   c
BL  Lacs   5   36   7   4.0   1.0 10
2
10
{\begin{tabular*}{\columnwidth}{@{}l@{\extracolsep{\fill}}c@{\extracolsep{\fill}}c
@{\extracolsep{\fill}}c@{\extracolsep{\fill}}c@{\extracolsep{\fill}}c@{\extracolsep{\fill}}c@{}}
\Hline   Class   &   $\gamma   _1$   &   $\gamma   _2$   &   $\langle   \gamma   \rangle$   &
$G$   &   $f$   &   $\theta   _{\rmn{c}}$   \\   \hline   BL   Lacs   &5   &   36   &   7   &
$-4.0$   &   $1.0\times   10^{-2}$   &   10$^\circ$   \\   FSRQs   &   5   &   40   &   11   &
$-2.3$   &   $0.5\times   10^{-2}$   &   14$^\circ$   \\   \hline   \end{tabular*}}
\bigskip
\end{table}
As   with   gures,   cross-referencing   of   tables   is   encouraged.   For   example,   we   would   reference   Table   1   using
Table~\ref{symbols}.
Also  as   with  gures,   you  may  wish  to  process   your   document   with  the   default   two-column  option  to  determine
whether  or  not  tables  may  need  to  be  exteneded  over  two  columns  in  the  journal   version  of   the  paper.   If   you  have  a
table  that  is  to  extend  over  two  columns,  you  need  to  use  table*  instead  of  table,  as  for  gures.
4.5   Typesetting  Mathematics
4.5.1   Displayed  mathematics.   The  biom  class  le  will  set  displayed  mathematics  centered  in  the  width  of  a  column
in  the  nal  version  of  a  manuscript,  provided  that  you  use  the  L
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delimiters.
The  equation
p
i=1
i  = trace(S)
was  typeset  using  the  biom  class  le  with  the  commands
\[
\sum_{i=1}^p   \lambda_i   =   \rmn{trace}   (\mathbfss{S})
\]
Displayed  equations   should  not   be  numbered  unless   they  are  referenced  in  the  text.   For   such  referenced  equations,
cross-referencing  is  encouraged.  For  example,
\begin{equation}
(n-1)^{-1}   \sum^n_{i=1}   (X_i   -   \overline{X})^2.
\label{eq:samplevar}
\end{equation}
Equation~(\ref{eq:samplevar})   gives   the   formula   for   sample   variance.
4.5.2   Long  /  two  column  equations.   The  biom  class  le  provide  the  option  to  code  long  equations  in  the  paper;  i.e.,
equations  that  would  be  very  dicult  to  display  in  a  single  column  in  the  nal   version  of   a  manuscript.   To  code  the
long  equation,  following  coding  should  be  followed:
\begin{longequation}
\left(\begin{array}{cc}%
[\tau_i(D-\alpha_iW]^{-1}+(\eta_0I+\eta_1W)[\tau_2(D-\alpha_2W)]^{-1}(\eta_0I+\eta_1W)&
(\eta_0I+\eta_1W)[\tau_2(D-\alpha_2W)]^{-1}\\
{[}\tau_2(D-\alpha_2W)]^{-1}(\eta_0I+\eta_1W)&[\tau_2(D-\alpha_2W)]^{-1}
\end{array}
\right).
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\label{eq:samplelongeqn}
\end{longequation}
As  with  regular  displayed  equations,   long  equations  that  are  referenced  in  the  text  should  be  cross-referenced  using
the   \label  and  \ref  commands.   Use   of   the   longequation  environment   should  only  be   reserved  for   very  unusual
circumstances  where  it  would  be  impossible  for  an  expression  to  be  displayed  in  one  column  broken  over  several  lines.
Most  Biometrics  papers  will   not  use  this  feature.   You  may  wish  to  examine  recent  issues  of   the  journal   for  examples
where  a  longequation  was  necessary  and  for  example  of  how  they  may  be  avoided  in  many  instances.
In case of long equations,  the equation  is spread to the adjoining column to enhance readability.  To separate the text
in  the  columns  from  the  equation,   two  horizontal   rules  are  drawn  above  and  below  the  equation.   The  space  between
these  two  rules  is  variable  and  is  inserted  on  the  basis  of  the  hight  of  the  equation,  e.g.  3pc,  4pc,  5pc,  ...  To  align  long
equations  within  two  horizontal   rules  in  other  column  (as  per  the  Biometrics  style),   the  biom  class  le  provides  the
option \eqnbreaktop{...}. In \eqnbreaktop{...} the approx height of the long equation should be given, for example,
if  the  height  of  the  long  equation  is  5pc  then  the  value  coded  in  \eqnbreaktop  should  be  \eqnbreaktop{5pc}.
4.5.3   Bold  math  italic  /  bold  symbols.   To  get  bold  math  italic  you  should  use  \bmath,  e.g.
\[
d(\bmath{s_{t_u}})   =   \langle   [RM(\bmath{X_y}
+   \bmath{s_t})   -   RM(\bmath{x_y})]^2   \rangle
\]
to  produce:
d(stu
) = [RM(Xy  +st) RM(xy)]
2