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Biotechnology &
Biochemical Engineering
1
Objectives:
To encourages the students to work in the field of bio-chemical Industry.
The objective of this program is to introduce the basic concepts of bioprocessing to the chemical engineers.
Outcomes:
1.
Student will get well acquainted with intervention of chemical
engineering principles to biological process.
2.
Student will able to understand the concepts of enzyme
technology, immobilization technology, cell growth kinetics.
3.
Student will get knowledge of bioreactors, fermentation, sterilization
techniques, and media preparation.
4.
Student will get well acquainted with biological process specific reactor
design aspects.
5.
Student will get knowledge of downstream processing in fermentation
industries.
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Books
3
Biochemical Engineering fundamentals By
Bailey ollis
2. Bioprocess Engineering:-Basic concept by Shuler
& Kargi (PHI)
3. Biochemical Engineering:-principles & concepts
by Syed Tanveer Ahmed Inamdar(PHI)
4. Introduction to Biochemical Engineering by
D.G.Rao
1.
Introduction
4
Biotechnology : fusion of biology & technology
Biological agents
Production of useful products
Biochemical engineering
Application of chemical engineering principles to biological
systems
Biologically derived products
Scientific & engineering principle
Biological agents(enzyme ,cell or microbes)
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Benefits of Biotechnology
5
Medicine
Human
Veterinary
Biopharming
Environment
Agriculture
Food products
Industry and manufacturing
Activities Involved in Bioprocess Industry
6
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CELL
7
Cell- a discrete unit of life
Molecular biology- study of
molecules in cells
Cells as reactors
Metabolismprocesses
by
which organisms use nutrients
Catabolism- breaking down
materials
into
smaller
components
Anabolism- building
from smaller materials
tissues
Classification of Living Systems
8
Cell Type
Plant, Animal & Protists (microorganisms)
Unicellular organism- organism of one cell
Multi-cellular organism- organism of many cells
Prokaryote- cells that lack specific nucleus
Eukaryote- cells with well-defined nucleus
Classification of Protists
Prokaryotes
Eukaryotes
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Classification of living system
9
Biocatalyst: cells and enzymes
10
10-20 m
1-5 m
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Comparision
11
Components of Cell
12
Proteins
Nucleic Acid
Lipids & Membranes
Carbohydrates
Cell wall
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Chemical composition of cells
13
Elemental composition
C, H, N, P, O, S, Ash
Molecular analysis
Water, Protein, Nucleic Acid, Lipid, Population in culture, dry
wt in culture
The Hierarchy of biological
structure
Cells are building
blocks:
Tissue- collection of
cells with specific
functions
Organs- collections of
tissues with specific
functions
Organ systemscollections of organs
with specific functions
14
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15
16
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Biochemical Components
17
Proteins
Carbohydrates
lipids & Fats
nucleic acid
Enzymes