GENERIC NAME
SEVOFLURANE
BRAND NAME
CLASSIFICATION
MODE OF ACTION
Ultane
Anaesthetics - Local & General
Sevoflurane is a volatile halogenated general
anaesthetic which causes a reversible loss of
consciousness and pain sensation, suppression of
voluntary motor activity, modification of autonomic
reflexes, depression of the respiratory and CV systems.
It also has muscle relaxant properties.
Onset: Within 2 minutes.
Duration: 4-14 minutes.
Absorption: Absorbed on inhalation. Blood/gas partition
coefficient is low.
Distribution: Crosses placenta.
Metabolism: Up to 5% of the absorbed dose is
metabolised by the hepatic CYP2E1 isoenzyme.
Excretion: Eliminated in the urine as metabolites.
07/20/13 (Intra-operatively)
Sevoflurane is indicated for induction and maintenance
of general anesthesia in adult and pediatric patients for
inpatient and outpatient surgery.
hypersensitivity.
DATE ORDERED
DOSAGE
INDICATION
CONTRAINDICATIONS
ADVERSE EFFECTS
dystonic movements in children,
hepatitis, and seizure-like activity.
NURSING
RESPONSIBILITIES
postoperative
Unless otherwise directed by your doctor do not take
other central nervous system (CNS) depressants
(medicines that may make you drowsy or less alert) for
about 24 hours after you have received sevoflurane.
Taking these medicines may add to the effects of
sevoflurane. Some examples of CNS depressants are
antihistamines or medicine for hay fever, other
allergies, or colds; other sedatives, tranquilizers, or
sleeping medicine, prescription pain medicine or
narcotics; barbiturates; medicine for seizures; and
muscle relaxants.