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Urine Drug Screening

This document provides information about drug screening cutoff levels and the length of time common drugs can be detected in urine. It outlines the initial and confirmatory cutoff levels used in workplace drug testing for marijuana, cocaine, opiates, and phencyclidine. It also lists potential agents that could cause false positive results on drug screening tests for various substances like marijuana, cocaine, opioids, phencyclidine, and amphetamines. Finally, it indicates the typical detection windows for various drugs in urine, ranging from a day for alcohol to over 30 days for regular marijuana use.

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Humaira Azmi
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670 views1 page

Urine Drug Screening

This document provides information about drug screening cutoff levels and the length of time common drugs can be detected in urine. It outlines the initial and confirmatory cutoff levels used in workplace drug testing for marijuana, cocaine, opiates, and phencyclidine. It also lists potential agents that could cause false positive results on drug screening tests for various substances like marijuana, cocaine, opioids, phencyclidine, and amphetamines. Finally, it indicates the typical detection windows for various drugs in urine, ranging from a day for alcohol to over 30 days for regular marijuana use.

Uploaded by

Humaira Azmi
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Urine Drug Screening: Practical Guide for Clinicians1

Federal Workplace Cutoff Values


Substance
Marijuana
Cocaine metabolites
Opiate metabolites
Phencyclidine
Amphetamines
Methamphetamine

Initial drug test


level
(immunoassay)
(ng/mL)
50
300
2000
25
1000
Incomplete
data

Confirmatory
drug test level
(GC-MS)
(ng/mL)
15
150
2000
25
500
500

Summary of Agents Contributing to Positive Results by Immunoassay


Substance tested via
immunoassay
Alcohol
Amphetamines

Length of Time Drugs of Abuse


Can Be Detected in Urine
Drug
Alcohol
Amphetamine
Methamphetamine
Barbiturate
Short-acting
Long-acting
Benzodiazepine
Short-acting (e.g., lorazepam)
Long-acting (e.g., diazepam)
Cocaine metabolites
Marijuana
Single use
Moderate use (4 times/wk)
Daily use
Long-term heavy smoker
Opioids
Codeine
Heroin (morphine)
Hydromorphone
Methadone
Morphine
Oxycodone
Propoxyphene
Phencyclidine

24 h
3 wk
3d
30 d
2-4 d
3d
5-7 d
10-15 d
>30 d

Cannabinoids

Dextroamphetamine

Opioids, opiates, and


heroin

Trimethobenzamide
Trmipramine
Benzodiazepines

Substance tested via


immunoassay

Short-chain alcohols
(isopropyl alcohol)
Amantadine
Benzphetamine
Bupropion
Chlorpromazine
Clobenzorex
l-Deprenyl
Desipramine

Ephedrine
Fenproporex
Isometheptene
Isoxsuprine
Labetalol
MDMA
Methamphetamine
l-Methamphetamine
(Vick's inhaler)
Methylphenidate
Phentermine
Phenylephrine
Phenylpropanolamine
Promethazine
Pseudoephedrine
Ranitidine
Ritodrine
Selegiline
Thioridazine
Trazodone

Time
7-12 h
48 h
48 h

48 h
48 h
2-4 d
3d
48-72 h
2-4 d
6-48 h
8d

Potential agents causing


false-positive result

Cocaine

Potential agents causing


false-positive result
Dronabinol
Efavirenz
Hemp-containing foods
NSAIDs
PPIs
Tolmetin
Coca leaf tea
Topical anesthetics
containing cocaine
Dextromethorphan
Diphenhydramine
Heroin
Opiates
Poppy seeds
Quinine
Quinolones
Rifampin
Verapamil and metabolites

Phencyclidine

TCAs

Oxaprozin
Sertraline

1) Moeller KE, Lee KC, Kissack JC. Urine Drug Screening: Practical Guide for
Clinicians. Mayo Clin Proc. 2008;83(1)66-76.
Information compiled by Keegan Harse, PharmD Candidate. June 2008.

Dextromethorphan
Diphenhydramine
Doxylamine
Ibuprofen
Imipramine
Ketamine
Meperidine
Mesoridazine
Thioridazine
Tramadol
Venlafaxine,
O-desmethylvenlafaxine
Carbamazepine
Cyclobenzaprine
Cyproheptadine
Diphenhydramine
Hydroxyzine
Quetiapine

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