The nutritional properties of
palm oil
          Professor Tom Sanders
           Nutritional Sciences Division
             Kings College London
Palm Tree and Fruit
                    Palm oil
 Palm (mesocarp) oil
   Crude palm oil  high beta-carotene
     Refined palm oil  low in beta-carotene
        Palmolein
        Super palmolein
   Palm kernel oil
     High in medium chain fatty acids
Palm oil and fractions
Hierarchy in
Hierarchy in Scientific
             Scientific Evidence
                        Evidence
                          Systematic
                          Systematic Reviews
                                      Reviews
 High                       (Meta-analysis)
                             (Meta-analysis)
 High
                       Randomized
                       Randomized Controlled
                                  Controlled Trials
                                             Trials
                  ce
           Evidence
                         Other
                         Other Controlled
                               Controlled Trials
                                          Trials
        of Eviden
                        Prospective
                        Prospective Cohort
                                    Cohort studies
                                           studies
  Level of
                         Case
                         Case  Control
                                 Control studies
                                         studies
  Level
                           Prevalence
                           Prevalence studies
                                      studies
 Low                        Ecological
                            Ecological studies
                                       studies
 Low
                              Animal
                              Animal studies
                                     studies          6
7
   Blood lipid metrics of risk of CHD
                                                                8
Prospective Studies Collaboration. Lancet 2007;9602:1829-1839
   Predicted changes () in the ratio of serum total to HDL cholesterol and in LDL- and HDL-
    cholesterol concentrations when carbohydrates constituting 1% of energy are replaced
      isoenergetically with saturated, cis monounsaturated, cis polyunsaturated, or trans
                                  monounsaturated fatty acids
             Mensink, R. P et al. Am J Clin Nutr 2003;77:1146-1155
Copyright 2003 The American Society for Nutrition
       Predicted changes in the ratio of serum total to HDL cholesterol and in LDL- and HDL-cholesterol
   concentrations when carbohydrates constituting 1% of energy are replaced isoenergetically with lauric acid
                     (12:0), myristic acid (14:0), palmitic acid (16:0), or stearic acid (18:0)
              Mensink, R. P et al. Am J Clin Nutr 2003;77:1146-1155
                                                                                                     10
Copyright 2003 The American Society for Nutrition
Predicted changes () in the ratio of serum total to HDL cholesterol when mixed fat constituting
10% of energy in the "average" US diet is replaced isoenergetically with a particular fat or with
                                          carbohydrates
             Mensink, R. P et al. Am J Clin Nutr 2003;77:1146-1155
Copyright 2003 The American Society for Nutrition
 Effect on risk of CHD events of replacing
5% energy saturated fatty acids from pooled
        analysis of 11 cohort studies
 Jakobsen M et al. Am J Clin Nutr 2009;89:1-8.   12
13
Meta-analysis of trans fatty acids on risk of CHD events
                                                           14
Replacing 2% trans fatty acids with saturated or
 unsaturated fatty acids reduces risk of CHD
                                                   15
 WHO/FAO 2009
   The technical need for high
        melting point fats
 Bakery products
 Spreads
                                 16
 Sources of high melting point fats
 Animal fats  lard/butter/ suet (cholesterol,
  trans in ruminant fats)
 Partially hydrogenated vegetable oils
  (trans 15-50% fatty acids)
 Fully hydrogenated and inter-esterified
  vegetable oils (low trans, high stearic acid
  rich, but not clean label)
 Palm oil fractions
                                              17
         Comparison of palm oil (PA), soybean oil (SO)peanut oil (PE)
         and lard (LA) on plasma lipids
                                  Lard
                        Palm
             Zhang, J. et al. J. Nutr. 1997;127:509S
Copyright 1997 American Society for Nutrition
                Palm oil vs Lard
100%
 90%
 80%
 70%
 60%                                                   PUFA
 50%                                                   MUFA
 40%                                                   Saturated
 30%
 20%
 10%
 0%
              Palm oil                 Lard
The fats differ mainly by the position of saturated fatty
acids.
In palm oil they are in the sn-1 and sn-3 position whereas
in lard they are in the sn-2 position
                                                              19
      Palm oil
G
L      Palmitic
Y
C
    Oleic/Linoleic
E
R
O    Palmitoleic
                     20
        The sn-2 hypothesis
 The adverse health effects of animal
  sources of saturated fatty acids are a
  consequence of the high proportion of
  saturated fatty acids in the sn-2 position
                                                21
     Comparisons of palm olein with partial hydrogenated
   soybean oil and fully hardened (PHSO and interesterified
    soybean oil (IE) on plasma total cholesterol (TC), HDL
         cholesterol (HDL-C) and the TC/HDL ratio
                                              P=0.001
Sundram et al. Nutrition & Metabolism 2007,               22
4:3doi:10.1186/1743-7075-4-3
 Summary of effects of palm oil
 on blood lipids and risk of CHD
 The blood cholesterol raising effects of
  palm oil fractions are lower than predicted
  from their fatty acid composition
 Palm oil fractions increase HDL
  cholesterol compared with carbohydrate or
  trans fatty acids
 The effects of replacing 5% energy as
  palm oil in the diet is unlikely to influence
  risk of CHD
                                              23