HEADACHE
DIFFERENTIAL DIAGNOSIS
       Vacular               Infection                  Vision-threatening                 Increase ICP           Dissection
1. SAH                    1. Meninigits       1.   temporal arteritis              1. SOL: tumor, abscess,       Carotid
2. Haematoma              2. encephalitis     2.   acute glaucoma                     cyst                       dissection
3. Cerebral venous                            3.   pituitary apoplexy              2. Cerebral oedema:
   sinus thrombosis                           4.   post. Leucoencephalopathy          trauma, altitude
4. Cerebellar infarct                         5.   cavernous sinus thrombosis      3. Hydrocephalus
                                                                                   4. Malignant hypertension
 Red flags:                                                           Causes of Non-sinister headache
  1. Decreased level of conscioussness (LOC)                           1. Tension-type headache
        SAH: headache +decreased LOC                                       Bifrontal pain,episodic, occuring with variable
        Subdural haematoma: head injury+ fluctuating                          frequency, describe as P or tightness around
          consciousness                                                        head like tighterning band, duration: few hours
        Extradural haematoma: head injury+ altered                         Pt still can continue normal activity with the
          consiousness following lucid interval                                headache (not severely disabling)
  2. Sudden onset worse headache ever                                       Trigger: stress, fatigue
        SAH: blood in CSF iritating the meningitis                    2. Migraine
  3. Seizure                                                                Recurrent & unilateral headache
  4. Focal neurological deficit:                                            Throbbing/pulsatile headache
        Intracranial pathology:                                            Migraine with aura
             limb weakness, speech problem                                 Duration: 4-72hr
             e.g: tumour                                                   sensitive to light, sound, smell
        3rd nerve palsy:                                                   They are vulnerable to mediction overuse
             presentation: ptosis, mydriasis (dilated pupil), eye             headache from tx for their migraine
               deviated down & out                                          Trigger: stress, food (cheese, caffeine)
             e.g: SAH due to ruptured aneurysm of post                     Ddx for migraine without aura: TIA
               commnunicating artery (PCOM)                            3. Sinusitis
        6th nerve palsy:                                                    Facial pain coming on over hours to days a/w
             presentation: convergent squint/failure to abduct                coryzal symptoms
               eye laterally                                                 Pain is tight as tension headache
             e.g: 6th CN get compressed by mass as this                     Exacerbated by movement
               nerve has longest intracranial course                         Duration: several days with time course
        12th nerve palsy:                                                     consistent with infection
             presentation: tongue deviation                           4. Medication overuse headache
             e.g: carotid artery dissection                                 Headache resemble either migraine or tension-
        Horners syndrome:                                                    type headache
             triad of partial ptosis, miosis (constricted pupil) &          Tx: withdrawal from analgesic use
               anhydrosis (dry skin around orbit)                      5. TMJ syndrome (headache +pain w jaw fx)
             due to interuption of ipsilateral sympathetic                  20-40y/o, F>M
               pathway                                                       dull ache in masseter muscle/preauricular pain
             e.g: carotid artery dissection (ask neck pain) &                 that may radiate to jaw or ear
               cavernous sinus lesion.                                       provoked by use of masseter muscle (eating)
  5. Absence of previous episodes                                            pt c/o hearing a click, grinding noise when they
        New onset of headache in >50y/o: think of temporal                    move their jaw, decrease mandibular range of
          arteritis                                                            motion
  6. Reduced visual acuity                                                   ear pain: trigeminal nerve also supply middle ear
        Temporal arteritis: in elderly                                        muscles
        TIA: Amourasis fugax +but rarely cause headache               6. Trigeminal neuralgia (intense, sharp stabbing pain)
        Carotid artery dissection: cause loss of vision due to              60-70y/o, F>M
          reduce blood flow to retina                                        unilateral facial pain involving division of
  7. Persistent headache, worse when lying down, early                         trigeminal nerve (V2/V3)
     morning nausea                                                          Duration: pain last only seconds, 100x/day
        High ICP: Worse when lying flat for prolonged times                 Trigger: eating, laughing, talking, touching
          (overnight) due to effect of gravity but can occur                   affected area
          when pt is bending over                                            Pt avoid known trigger like shaving
        Reduced ICP: common after LP + Headache worse                 7. Cluster headache
          when standing up suggested reduced ICP                             M>F
  8. Progressive, persistent headache                                        Occur at exatcly the same time every day or night
        Expanding SOL: tumour, abscess, cyst, haematoma                     Duration:clusters for 6-12 weeks every 1-2years
  9. Constitutional symptoms:                                                Pain focused over one eye
        Malignancy/TB/chronic inflammation (temporal                        Red watery eye, rhinorrhea, Horner syndrome
          arteritis): Weight loss, night sweats, or fever                    Severely painful & disabling but often occur at
                                                                               night, allowing daytime duties to continoue
                                                                             Trigger: Alcohol