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Calcipotriol Monohydrate

Calcipotriol monohydrate BP is a white or almost white crystalline powder with the chemical name (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1a,3b,24-triol monohydrate and molecular weight of 430.6. It is practically insoluble in water but freely soluble in ethanol and slightly soluble in methylene chloride, and it is sensitive to light with its activity due to both calcipotriol and its reversible isomer pre-calcipotriol in solution.

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96 views1 page

Calcipotriol Monohydrate

Calcipotriol monohydrate BP is a white or almost white crystalline powder with the chemical name (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1a,3b,24-triol monohydrate and molecular weight of 430.6. It is practically insoluble in water but freely soluble in ethanol and slightly soluble in methylene chloride, and it is sensitive to light with its activity due to both calcipotriol and its reversible isomer pre-calcipotriol in solution.

Uploaded by

Jai Murugesh
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Calcipotriol Monohydrate BP

Chemical Name : (5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-


5,7,10(19),22-tetraene-1a,3b,24-triol monohydrate.

Empirical Formula : C27H40O3,H2O

Molecular Weight : 430.6

Chemical Structure :

Description : White or almost white, crystalline powder.

Solubility : Practically insoluble in water, freely soluble in


ethanol (96 per cent), slightly soluble in methylene
chloride.
It is sensitive to light.
A reversible isomerisation to pre-calcipotriol takes
place in solution, depending on temperature and
time. The activity is due to both compounds.

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