Educational Strategies To Promote Clinical Diagnostic Reasoning
Educational Strategies To Promote Clinical Diagnostic Reasoning
review article
                                    medical Education
                         Malcolm Cox, M.D., and David M. Irby, Ph.D., Editors
C
        linical teachers differ from clinicians in a fundamental way.                            From the Department of Medicine, Ore-
        They must simultaneously foster high-quality patient care and assess the clin-           gon Health and Science University, Port-
                                                                                                 land. Address reprint requests to Dr. Bow-
        ical skills and reasoning of learners in order to promote their progress toward          en at the Department of Medicine, 3181
independence in the clinical setting.1 Clinical teachers must diagnose both the pa-              S.W. Sam Jackson Park Rd., L-475, Port-
tients clinical problem and the learners ability and skill.                                    land, OR 97239, or at bowenj@ohsu.edu.
    To assess a learners diagnostic reasoning strategies effectively, the teacher needs         N Engl J Med 2006;355:2217-25.
to consider how doctors learn to reason in the clinical environment.2-4 Medical stu-             Copyright  2006 Massachusetts Medical Society.
dents in a classroom generally organize medical knowledge according to the structure
of the curriculum. For example, if pathophysiology is taught according to organ sys-
tems, then the students knowledge will be similarly organized, and the recall will be
triggered by questions related to specific organ systems or other contextual clues. In
the clinical setting, the patients health and care are the focus. Clinical problems may
involve many organ systems and may be embedded in the context of the patients
story and questions. Thus, in the clinical setting, the students recall of basic science
knowledge from the classroom is often slow, awkward, or absent. Only after learners
make new connections between their knowledge and specific clinical encounters can
they also make strong connections between clinical features and the knowledge
stored in memory.5,6 This report focuses on how clinical teachers can facilitate the
learning process to help learners make the transition from being diagnostic novices
to becoming expert clinicians.
Di agnos t ic R e a s oning
There is a rich ongoing debate about our understanding of the complex process of
clinical diagnostic reasoning.2,3 In this report, some of the basic processes involved
in clinical reasoning, as understood according to current knowledge, are translated
into practical and specific recommendations for promoting the development of strong
diagnostic reasoning skills in learners. The recommendations are illustrated by a clini-
cal case presentation.
   Clinical teachers observe learners gathering information from patients, medical
records, imaging studies, results of laboratory tests, and other health care providers.
On the basis of their observations, and through the discussion of clinical cases, teach-
ers draw conclusions about the learners performance, including their reasoning pro-
cesses. A hypothetical case provides an example of a conversation involving a patient,
two learners with different levels of expertise, and the clinical teacher (see Box). In
this case,7-9 a patient with knee pain makes an urgent visit to an ambulatory care
practice. A novice resident (with relatively little experience with this patients prob-
lem, which is gout) and an expert resident (who is familiar with this problem, hav-
ing seen other patients with gout) each independently interviews the patient, performs
                 an examination, presents the case to the precep-                patient as seen through the residents eyes. On the
                 tor, and separately discusses the case with the                 basis of the case presentations by both the expert
                 preceptor. As becomes evident, the expert resident              and the novice residents, the teacher may or may
                 has transformed the patients story into a mean-                not have had a firm idea of what was wrong with
                 ingful clinical problem. The novice resident has                the patient. Rather than offer an opinion, however,
                 also transformed the patients story, but less elabo-           the teacher asked the expert resident to reason
                 rately. What the teacher hears from both resi-                  aloud about the case, thereby providing the teach-
                 dents differs substantially from what the patient               er with additional clinical information about the
                 told them.                                                      patient as well as considerable insight into the
                     The expert resident brought two sets of skills              residents clinical reasoning skills. The teacher
                 to the encounter with the patient. First, this resi-            used the same strategy with the novice resident,
                 dent probably formed an early impression  a                    and although the result added little information
                 mental abstraction  of the patients story. Al-                about the patient, the teacher learned something
                 though possibly unaware of this formulation, the                about the novice residents limited clinical rea-
                 residents mental abstraction influenced his diag-              soning.
                 nostic strategy. Guided by his early impression, the               Key elements of clinical diagnostic reasoning
                 resident probably asked a series of questions, and              are shown in Figure 1. The first step in diagnostic
                 the patients responses guided both further ques-               reasoning, which is based on knowledge, experi-
                 tioning and the planning of a focused physical                  ence, and other important contextual factors,10 is
                 examination. The residents approach involved a                 always data acquisition. Data acquisition, depend-
                 search for information that could be used to dis-               ing on the setting, may include elements of the
                 criminate among any number of diagnostic expla-                 history, the findings on physical examination, and
                 nations of the patients problem. The novice resi-              the results of laboratory testing and imaging stud-
                 dent might not have formed a mental abstraction                 ies. Another early step is the creation of the men-
                 of the case and probably was not sure which ques-               tal abstraction or problem representation,2,8,11
                 tions to pose to the patient.                                   usually as a one-sentence summary defining the
                     Second, the expert residents clinical case pre-            specific case in abstract terms. Clinicians may
                 sentation was a succinct summary of the findings,               have no conscious awareness of this cognitive step.
                 providing the teacher with a clinical picture of the            The problem representation, unless elicited in the
                   Patients story: My knee hurt me so much last night, I woke up from sleep. It was fine when I went to bed. Now its
                       swollen. Its the worst pain Ive ever had. Ive had problems like this before in the same knee, once 9 months ago
                       and once 2 years ago. It doesnt bother me between times.
                   Novice residents presentation: My next patient       Expert residents presentation: My next patient is a 54-year-old white
                     is a 54-year-old white man with knee pain.             man with a sudden onset of pain in his right knee that awak-
                     It started last night. He does not report any          ened him from sleep. He does not report any trauma and was
                     trauma. On examination, his vital signs are            essentially asymptomatic when he went to bed. His history is re-
                     normal. His knee is swollen, red, and tender           markable for two episodes of similar, severe pain 9 months
                     to touch. It hurts him a lot when I test his           and 2 years ago. He is pain-free between episodes. He is afe-
                     range of motion. Hes had this problem                 brile today. His knee is swollen, tender to touch, and erythem-
                     twice before.                                          atous.
                   Teachers inquiry: What do you think is causing this patients knee pain?
                   Novice residents response: It could be an in-        Expert residents response: The patient has acute gout. He has had
                     fection. It could be a new onset of rheuma-            multiple discrete episodes with abrupt onset of extremely se-
                     toid arthritis. It could be Lyme disease.              vere pain involving a single joint with evidence of inflamma-
                     Since he doesnt recall falling, I doubt its          tion on examination. Before all his episodes, he is asymptom-
                     an injury. I dont know whether osteoarthri-           atic. I would have expected gout to affect the first metatarso-
                     tis ever presents like this, but he does have a        phalangeal joint, but it can present in the knee. Nothing sug-
                     history of knee pain.                                  gests any ongoing, chronic problem in the knee. I dont see
                                                                            any portal of entry to suggest acute infectious arthritis and he
                                                                            looks quite well for that. His other joints are normal on exami-
                                                                            nation. I doubt that he has a flare-up of osteoarthritis with
                                                                            pseudogout or a systemic, inflammatory arthritis such as
                                                                            rheumatoid arthritis.
                                                                                                                                                                                                                                                    tion accordingly.
                                                                                                                                                      Problem repre-     Disorganized presentation,       Learner has no experience with this     Go to the bedside, examination room, or       Now that weve reviewed the important find-
                                                                                                                                                         sentation          discussion, or both.             clinical problem or lacks a con-       medical record and elicit or confirm          ings, lets think together about how they point
                                                                                                                                                                                                             ceptual approach to it.                important findings; think aloud with          to acute arthritis as the likely problem. Im
                                                                                                                                                                                                                                                    the learner, linking important findings       considering acute arthritis because. . . .
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                                                                                                                                                      Generation of     Multiple diagnoses generat-       Learner has not identified a prob-      Ask the learner to list all important find-   What are the main findings? Can you summa-
                                                                                                                                                                                                                                                                                                                                                       n e w e ng l a n d j o u r na l
hypothesis: ed in a random order lem representation or formulated ings from the case, create a problem rize these in abstract terms in one or two sen-
                                                                                                                                                         Search for and   with no attempt to prior-          illness scripts for the diagnostic     representation based on selected              tences? What are the diagnostic consider-
                                                                                                                                                         selection of     itize them.                        considerations.                        findings, and prioritize diagnostic           ations for patients with acute arthritis? Which
                                                                                                                                                         illness script                                                                             considerations that identify discrimi-        cause of acute arthritis is most likely to be
                                                                                                                                                                                                                                                    nating features for each consideration.       correct in this case? Why?
                                                                                                                                                                         Discussion of differential di-   Learner has not formulated illness      Ask the learner to support his or her di-     What are your main and alternative diagnoses?
                                                                                                                                                                            agnosis not linked to            scripts for the diagnostic consid-     agnosis using findings from the case;         What features of the case helped you to dis-
                                                                                                                                                                            findings from the case.          erations or is unable to compare       then ask for at least one additional          criminate between them?
                                                                                                                                                                                                             and contrast relevant illness          plausible diagnosis and have learner
                                                                                                                                                                                                             scripts.                               compare it with alternative diagnostic
                                                                                                                                                                                                                                                    possibilities. If necessary, provide
                                                                                                                                                                                                                                                    your own analysis of the case.
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                                                                                                                                                      Cognitive feed-   Far-fetched diagnosis.          Learner has a poor understanding         Ask the learner to describe the prototypi-    What is the classic presentation for your diag-
                                                                                                                                                         back                                             of the case or lacks a sense of          cal presentation for this particular di-      nosis? What findings in this case fit the typical
                                                                                                                                                                                                          relative probability.                    agnosis, to be followed by a compari-         presentation? Are there enough key features
                                                                                                                                                                                                                                                   son with the findings in this case;           present to continue with this line of reasoning?
                                                                                                                                                                                                                                                   identify additional data that would be        What else do we need to know about this pa-
                                                                                                                                                                                                                                                   needed to rule in the diagnosis.              tient?
                                                                                                                                                      Developmental     Presentation or reasoning       Learner has not created an anchor      Ask the learner about his or her experi-      Have you taken care of other patients with
                                                                                                                                                         stage            below the expected              prototype in memory, has too lit-        ence with this type of case or problem;       acute arthritis? What do you remember about
                                                                                                                                                                          level for a common prob-        tle experience with this type of         assign the learner patients who have          those patients? I want you to read about the
                                                                                                                                                                          lem.                            problem to create illness scripts,       common problems and prototypical              typical presentation of gout and compare it
                                                                                                                                                                                                          or both.                                 presentations; instruct the learner           with the typical presentation of infectious ar-
                                                                                                                                                                                                                                                   when reading about the case to com-           thritis. Identify key and discriminating features
                                                                                                                                                                                                                                                   pare the primary diagnosis with at            for both diagnoses. Tomorrow, tell me what
                                                                                                                                                                                                                                                   least one other consideration, identi-        you have learned.
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                                                                                                                                                         siderations      of a complex and ill-          tation is possible, there is a risk        tations; ask the learner to identify and     ed by the clinical findings. Choose a reason-
                                                                                                                                                                          defined clinical problem.      of premature closure (learner              defend primary and secondary diag-           able alternative diagnosis and tell me why it
                                                                                                                                                                                                                                                                                                                                                     medical Education
                                                                                                                                                                                                         may be making a lucky guess), or           noses, using key and discriminating          does not fit the clinical findings.
                                                                                                                                                                                                         both.                                      features of the case; articulate your      (Repeat this procedure for each plausible prob-
                                                                                                                                                                                                                                                    own problem representations and              lem representation.)
                                                                                                                                                                                                                                                    clinical reasoning.
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                                                                                                                                      2223
                                               The   n e w e ng l a n d j o u r na l     of   m e dic i n e
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