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Caenorhabditis Elegans: Espineda. Estevanez. Natividad. Urbano

The document summarizes key aspects of the nematode Caenorhabditis elegans. C. elegans is a small roundworm commonly used for biological research. It has a short life cycle, compact genome, and is easy to propagate, making it advantageous to study. The document describes C. elegans' life cycle, gametogenesis, development through cleavage and gastrulation stages, organogenesis, and the roles of the anchor cell and distal tip cells. It also notes C. elegans' contribution to the discovery of programmed cell death.

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39 views20 pages

Caenorhabditis Elegans: Espineda. Estevanez. Natividad. Urbano

The document summarizes key aspects of the nematode Caenorhabditis elegans. C. elegans is a small roundworm commonly used for biological research. It has a short life cycle, compact genome, and is easy to propagate, making it advantageous to study. The document describes C. elegans' life cycle, gametogenesis, development through cleavage and gastrulation stages, organogenesis, and the roles of the anchor cell and distal tip cells. It also notes C. elegans' contribution to the discovery of programmed cell death.

Uploaded by

Courtney
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Caenorhabditis elegans

Espineda. Estevanez. Natividad. Urbano.


Caenorhabditis elegans
- small, free-living soil nematode (roundworm) that lives in many parts of the
world and survives by feeding on microbes, primarily bacteria.
- advantages for study
- short life cycle
- compact genome
- ease of propagation
- small size
Caenorhabditis elegans (Hermaphrodite)

Caenorhabditis elegans (Male)


LIFE CYCLE OF C. ELEGANS
GAMETOGENESIS
CHROMOSOME
NUMBER:

EGG SIZE SPERM SIZE


TYPE
GAMETOGENESIS
DEVELOPMENT OF C. ELEGANS
CLEAVAGE
What are P-granules in the C. elegans embryo?

They are visible granules that congregate in the

region of the posterior blastomeres that become

the germ cells.


CLEAVAGE
CLEAVAGE

WHAT ARE PAR PROTEINS AND THEIR SIGNIFICANCE?


What are the functions of the anchor cell and the distal tip

cells in C. elegans?

They both emit important developmental signals in

postembryonic life. The anchor cell controls the

formation of the vulva from adjacent cells of the

hypodermis. The distal tip cells of the gonads maintain

nearby germ cells in mitosis.


CYTOPLASMIC DETERMINANTS

BE ABLE TO EXPLAIN
THIS WELL
How do the PAR proteins operate to create asymmetry within the C. elegans zygote?

PAR-3 forms a complex with PAR-6 and aPKC. This is repelled by the sperm aster, and the end to

which it moves becomes the anterior. The complex then repels PAR-1 and PAR-2 to the posterior end.

These localizations of PAR proteins are achieved mostly by differential protein degradation. The

consequence is the localization of various transcription factors that control the specification of the early

blastomeres.
GASTRULATION
CELL LINEAGE

BE ABLE TO EXPLAIN
THIS WELL
ORGANOGENESIS
ORGANOGENESIS

What are the functions of the anchor

cell and the distal tip cells in C.

elegans?

They both emit important

developmental signals in

postembryonic life. The anchor cell

controls the formation of the vulva

from adjacent cells of the hypodermis.

The distal tip cells of the gonads

maintain nearby germ cells in mitosis.


APOPTOSIS

WHAT IS THE
CONTRIBUTION OF C.
ELEGANS IN THE
DISCOVERY OF
PROGRAMMED CELL
DEATH?

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