Surgical Treatment Guidelines
Surgical Treatment Guidelines
Ministry of Health
                        P. O. Box 84 Kigali
                         www.moh.gov.rw
            Surgery
C l i n i c a l Tr e a t m e n t G u i d e l i n e s
September 2012
                       Ministry of Health
                        P. O. Box 84 Kigali
                         www.moh.gov.rw
             Surgery
 C l i n i c a l Tr e a tment G uidelines
September 2012
Acronyms...................................................................................................v
Foreword..................................................................................................vii
1. Orthopaedic Surgery.............................................................................1
   1.1.	Upper Limbs Fractures............................................................................4
         1.1.1.	 Distal Radius & Ulna fractures	...........................................4
         1.1.2.	 Forearm Shaft Fractures.........................................................5
         1.1.3.	 Distal Humerus Fractures.....................................................7
         1.1.4.	 Humeral Shaft Fracture.........................................................9
         1.1.5.	 Fractures of Proximal Humerus...........................................10
         1.1.6.	Tuberosity Fractures..............................................................10
         1.1.7.	 Clavicle Fractures..................................................................11
         1.1.8.	 Scapula Fractures..................................................................12
     1.7.	Dislocations...........................................................................................43
            1.7.1.	General Consideration.........................................................43
            1.7.2.	 Acromio-Clavicular Joint Dislocation...............................44
            1.7.3.	Shoulder Dislocations...........................................................45
            1.7.4.	 Elbow Dislocation.................................................................47
            1.7.5.	 Hip Dislocation.....................................................................48
            1.7.6.	 Traumatic Knee dislocation.................................................50
            1.7.7.	 Patellar Dislocation...............................................................52
4. Abdominal Injuries............................................................................123
   4.1.	 Specific Injuries	...................................................................................125
           4.1.1.	 Splenic Injury.......................................................................125
           4.1.2.	 Hepatic Injury.....................................................................125
           4.1.3.	Pancreatic Injury.................................................................126
           4.1.4.	Duodenal Injury..................................................................127
           4.1.5.	Small Bowel Injury..............................................................127
           4.1.6.	Colon Injury........................................................................128
           4.1.7.	Rectal Injury........................................................................128
7. Genito-Urinary Disorders..................................................................163
    7.1.	 Traumatic Disorders...........................................................................163
            7.1.1.	Renal Injuries.......................................................................163
            7.1.2.	Ureter Injury........................................................................164
            7.1.3.	Bladder Injury......................................................................165
            7.1.4.	Urethral Injury.....................................................................166
            7.1.5.	 Testicular Injury...................................................................166
8. Burns...................................................................................................207
   8.1.	Electrical Burns...................................................................................210
10. References.........................................................................................223
List of participants.................................................................................227
T
       he guidelines and protocols presented in this document are designed
       to provide a useful resource for healthcare professionals involved in
       clinical case management in Rwanda. They were developed by taking
into consideration services provided at different levels within the health
system and the resources available, and are intended to standardize care at
both the secondary and tertiary levels of service delivery across different
socio-economic levels of our society.
The Ministry of Health is grateful for the efforts of all those who contributed
in various ways to the development, review, and validation of the Clinical
Treatment Guidelines. We would like to thank our colleagues from District,
Referral, and University Teaching Hospitals, and specialized departments
within the Ministry of Health, our development partners, and private health
practitioners. We also thank the Rwanda Professional Societies in their
relevant areas of specialty for their contributions and for their technical
review, which enriched the content of this document, as well as the World
Health Organization (WHO) and the Belgium Technical Cooperation
(BTC) for their support.
We would like to especially thank the United States Agency for International
Development (USAID) for both their financial and technical support
through the Management Sciences for Health (MSH) Integrated Health
System Strengthening Project (IHSSP) and Systems for Improved Access to
Pharmaceuticals and Services (SIAPS).
To end with, we wish to express our sincere gratitude to all those who
continue to contribute to improving the quality of health care of the Rwanda
population.
Dr Agnes Binagwaho
Minister of Health
Causes
  -	   Pain
  -	   Swelling
  -	   Wounds
  -	   Deformity
  -	   Tenderness
  -	   Inability to move
  -	   Possibility of neurovascular deficit
General Investigations
  -	 Blood tests: Full Blood Count, Blood Group, PT, PTT and
     specific tests depending on patient condition and past medical
     history
  -	 X-ray
  -	 Ultrasound, CT-Scan, MRI as indicated
                                                                                     1
         	 Open injuries evaluation
                                                                                  Surgery
                                                                                  Orthopaedic
         	 Definitive care
         	 An open fracture is when disruption of the skin and
            underlying soft tissue results in communication between
            the fracture and the outside environment.
Management
  -	   Initial management
  -	   Adequate wound care and immobilization
  -	   Drugs therapy (VAT, SAT, analgesics, antibiotics)
  -	   DVT prophylaxis if indicated
  -	   Antibiotic: The choice of antibiotic to be used depends on the
       Fracture type and the likely contamination of the fracture site.
  -	   Grade 1: 1st generation cephalosporin
  -	   Grade 2: 1st generation cephalosporin + or  an aminoglycoside
       depending on the level of wound contamination.
  -	   Grade 3: 1st generation cephalosporin and an aminoglocoside
  -	   All forms of injuries are treated as Grade 3 with addition of
       penicillin to cover for staphylococcal infection
Note: For gustillo type III: External fixation is the golden standard
      form of fracture fixation and stabilisation
SPECIFIC FRACTURES
Fracture Classification
Management
    Aim
           	 To achieve anatomical reduction
    Anatomical Criteria of reduction: AP and lateral x- ray views
         	 Radial inclination 20-23 degrees,
         	 Volar tilt 11 degrees to 12 degrees
         	 Radial styloid length should be 1,5cm distal to ulnar styloid
                                                                                    1
1.1.2. Forearm Shaft Fractures
                                                                                 Surgery
                                                                                 Orthopaedic
Definition: It is a disruption of the bone continuity located between the
distal and proximal epiphysis.
Management
Management
  -	 Galeazzi fracture
        	 It is a fracture of the radial diaphysis at the junction of the
           middle and distal thirds with disruption of the distal radio-
           ulna joint (DRUJ)
Management
Management
    -	Children
         	 Closed reduction and immobilization
    -	Adult
         	 open reduction and internal fixation of the ulna plus closed
            reduction of the radial head, followed by immobilization
            for 3 weeks
 Note:
  -	 If closed reduction is not achievable, open reduction is required.
     Attention should be paid to the relationship between the annular
     ligament, the lateral epicondyle, and the radial head.
    -	 Entrapment of the soft tissues is the most common reason for
       inability to obtain concomitant closed radial head reduction at
       the time of open reduction and internal fixation of the ulna.
    -	 Fractures of both the Radius & Ulna, are usually the result
       of high-energy injuries. These fractures are usually displaced
       because of the force required to produce such an injury
                                                                                    1
Management
                                                                                 Surgery
                                                                                 Orthopaedic
  Undisplaced fracture (VERY RARE)
        	 Immobilization with long arm cast for 6 weeks with early
           digital active and passive motion exercises.
  Displaced fracture
        	 Open reduction and internal fixation with plate.
           (Alternative implants: intramedullary nails, flexible nails,
           pins)
INTERCONDYLAR FRACTURES
Management
  -	 Type I: Conservative treatment
  -	 Type II &III: Open Reduction and Internal Fixation (ORIF)
  -	 Type IV: Young patients: Bone reconstruction and grafting of
     articular defects
  -	 Elderly patients (osteopenic bone): Transolecranon traction or
     total elbow arthroplasty
OLECRANON FRACTURES
Management
Classification
    -	 Mason proposed a classification scheme for radial head fractures
         	 Type I is a nondisplaced fracture
         	 Type II is a fracture that is displaced usually involving a
            single large fragment
         	 Type III is a comminuted fracture
         	 Type IV is a fracture associated with an elbow dislocation
Management
                                                                                    1
  -	 Type III: Early radial head excision/arthroplasty
                                                                                 Surgery
                                                                                 Orthopaedic
  -	 Type IV: Reduction of elbow dislocation and excision if
     comminuted fracture/retain and fix radial head if no comminution
CAPITELLAR FRACTURES
Classification
Management
Management
  Non-operative methods
       	 Cast immobilization (shoulder spica, U-slab, Sarmiento
          cylinder cast etc.) leads to good results with high union rates.
  Operative treatment
       	 Special circumstances may merit open reduction and
          fixation
             	 Selected segmental fractures
             	 Inadequate closed reduction
             	 Floating elbow
             	 Bilateral humeral fractures
             	 Open fractures
             	 Multiple trauma
             	 Pathologic fractures
             	 Humerus fracture with associated vascular injuries
                requiring exploration may benefit from internal fixation
Fractures are classified by the number of parts that are displaced more
than 1 cm or angulated more than 45 degrees.
  -	Two part fractures
        	Anatomic neck fracture
        	Tuberosity fracture
        	Surgical neck fracture
Management
Note:
 -	 Closed reduction is difficult because of controlling the articular
    fragment
 -	 High risk of avascular necrosis of the humeral head
GREATER TUBEROSITY
  -	 Attempt closed reduction and immobilization
  -	 If irreducible fracture: ORIF (pins /screws)
  -	 If associated with shoulder dislocation:
          	 Simple reduction of the dislocation may reduce the
             tuberosity fracture
          	 If not: ORIF
                                                                                   1
LESSER TUBEROSITY
                                                                                Surgery
                                                                                Orthopaedic
  -	 If small fragment, closed reduction
  -	 If larger fragments: ORIF
Classification (Allman)
Management
  -	 Non-operative treatment (arm sling, figure-of-eight brace or
     universal shoulder immobilizer)
Classification (AO/OTA)
  -	 Type A: Extraarticular
  -	 Type B: Body of scapula fracture
  -	 Type C: Intraarticular glenoid fracture
Management
  Non-operative treatments
       	 Sling use and early range of motion
                                                                                    1
1.2. Pelvic and lower limbs fractures
                                                                                 Surgery
                                                                                 Orthopaedic
1.2.1.	 Pelvic Ring Disruption
Classification (Tile)
Management
After rapid resuscitation, assess of personality of injury including stability of the ring
                                                                                      1
PELVIC RING UNSTABLE (TYPE C)
                                                                                   Surgery
                                                                                   Orthopaedic
                   Unstable pelvic ring fracture (Type C)
    Posterior satisfactory
                                                  Position unsatisfactory or
                                                 polytrauma or open fracture
Continue external fixation plus
          traction
Classification (Letournel)
  -	 Type A: Partial articular fractures, one column involved
       	 A1: posterior wall fracture
       	 A2: posterior column fracture
       	 A3: anterior wall or anterior column fracture
                                                                                      1
Management
                                                                                   Surgery
                                                                                   Orthopaedic
The goal of treatment is to attain a spherical congruency between the
femoral head and the weight-bearing acetabular dome, and to maintain
it until bones are healed.
                                       Osteosythesis with
                                            screws
Necrosis or
Malunion Necrosis or
Malunion
      Hip prosthesis or
         osteotomy                                            Hip prothesis
INTERTROCHANTERIC FRACTURES
These fractures usually occur along a line between the greater and the
lesser trochanter.
Management
  Initial treatment
         	 Skin traction to minimize pain and further displacement
  Definitive treatment
        	 Depends upon the general condition of the patient and the
           fracture pattern
        	 Operative treatment within 48 hours is preferred
       	 Reduction and internal fixation with sliding hip screw
           (DHS, RSP etc.)
       	 The patient can be taken out of bed the next day
       	 Weight bearing with crutches or a walker is begun as soon
           as pain allows
                                                                                     1
         	 The fracture usually heals in 612 weeks
                                                                                  Surgery
                                                                                  Orthopaedic
  Alternatives
        	 Second-generation interlocked nails (PFN, IMHS, Gamma
           nails etc.)
SUBTROCHANTERIC FRACTURES
Classification (Russell & Taylor)
  -	 Type IA
       	 Fractures do not involve the piriformis fossa
       	 Lesser trochanter attached to the proximal fragment
  -	 Type IB
       	 Fractures do not involve the piriformis fossa
       	 Lesser trochanter is detached from the proximal fragment
  -	 Type II: Fractures have fracture extension into the piriformis
     fossa
Management
  -	 Type I: ORIF with cephalo-medullary nail (gamma nails,
     intramedullary hip screws, PFN, Russel-Taylor and Trigen
     reconstruction nails etc.)
  -	 Type II: Is best treated with a sliding hip screw or fixed angle plate
Classification (Garden)
  -	   Type 1: Valgus impaction of the femoral head
  -	   Type 2: Complete but non displaced
  -	   Type 3: Complete fracture, displaced less than 50%
  -	   Type 4: Complete fracture displaced greater than 50%
This classification is of prognostic value for the incidence of avascular
necrosis: The higher the Garden number, the higher the incidence
Management
  Initial treatment
         	 Traction may offer comfort in some patients but do not
            improve overall outcome
  Definitive treatment
        	 Internal fixation
Classification (Winquist)
  -	 Type 1: Fracture that involves no, or minimal, comminution at
     the fracture site, and does not affect stability after intramedullary
     nailing
  -	 Type 2: Fracture with comminution leaving at least 50% of the
     circumference of the two major fragments intact
  -	 Type 3: Fracture with comminution of 50100% of the
     circumference of the major fragments.
  -	 Type 4: Fracture with completely comminuted segmental pattern
     with no intrinsic stability
Management
Treatment depends upon the age and medical status of the patient as
well as the site and configuration of the fracture.
  Conservative Treatment
        	 Is rarely indicated
  Operative Treatment
       	 Interlocking intramedullary nailing is the Golden standard
          treatment of femoral shaft fracture
  Alternative Treatment
       	 Non locked intramedullary nails (Kuntscher nail, flexible
          nails, AO nails etc.), do not provide ideal stable fixation
       	 Plates and screws: require significant soft-tissue dissection
          and opening of the fracture hematoma and can be
          associated with high rate of infection.
       	 External fixation: remains indicated in some open fractures
          and in polytrauma patients
These fractures involve the distal metaphysis and epiphysis of the femur.
Classification (AO/OTA)
  -	 Type A: Extraarticular
       	 A1: Simple fracture
       	 A2: Metaphyseal wedge fracture
       	 A3: Metaphyseal complex fracture
  -	 Type B: Unicondylar partial articular
       	 B1: Lateral condylar fracture
                                                                                     1
        	 B2: Medial condylar fracture
                                                                                  Surgery
                                                                                  Orthopaedic
        	 B3: Frontal fracture
  -	 Type C : Intercondylar/ bicondylar, complete articular
       	 C1: Articular simple, metaphyseal simple
       	 C2: Articular simple, metaphyseal complex
       	 C3: Multifragmentary articular fracture
Management
EXTRAARTICULAR FRACTURES
  Conservative treatment
        	 Skeletal traction treatment is reserved for patients for
           whom surgery is not possible due to comorbidities
  Operative treatment
      	 Retrograde intramedullary nailing
      	 Plates and screws (blade plates, locking plates, sliding plates)
      	 External fixator (Ilizarov frame etc.)
INTRAARTICULAR FRACTURES
  -	 Maximal functional recovery of the knee joint requires anatomic
     reduction of the articular components and restitution of the
     mechanical axis
  -	 Undisplaced intaarticular fractures: cast immobilization(6-8 weeks)
  -	 Displaced intraarticular fractures usually require open reduction
     and internal fixation with a variety of methods including:
  -	 Dynamic Compression Screws (DCS)
  -	 Plates and screws
Management
  Non displaced fractures
        	 Walking cylinder cast or brace for 68 weeks followed by
           knee rehabilitation.
  Displaced fractures
       	 Open reduction and immobilization by figure-of-eight
          tension banding over two longitudinal parallel K-wires.
Management
  Undisplaced or minimally displaced/ too comminuted to be fixed
        	 Conservative treatment by cylinder cast immobilization for
           6-8weeks
  Severe displacement
       	 Operative treatment by tension band wiring
       	 Alternative: excision of the patella and repair of the defect
           by imbrication of the quadriceps expansion
Classification (Schatzker)
  -	   Type I: split fracture of the lateral plateau
  -	   Type II: split-depression of the lateral plateau
  -	   Type III: depression of the lateral plateau
  -	   Type IV: medial plateau fracture
  -	   Type V: bicondylar fracture
  -	   Type VI: plateau fracture with metaphyseal-diaphyseal dissociation
Management
  Conservative treatment: Cast immobilization
       	 Articular step-off of 3 mm or less and condylar widening of
          5 mm or less can be treated conservatively
       	 Lateral or valgus tilt up to 5 degrees is well tolerated
  Operative treatment
      	 Medial plateau fractures with any significant displacement.
      	 Articular step-off >3 mm
      	 Bicondylar fractures with any medial displacement, valgus
          tilt >5 degrees or with significant articular step-off
                                                                                    1
  Minimal invasive treatment
                                                                                 Surgery
                                                                                 Orthopaedic
      	 Closed reduction under fluoroscopy plus percutaneous
         pinning/screws
      	 Minimally Invasive Plate Osteosynthesis (MIPO) and the
         Less Invasive Stabilization Systems (LISS) are used in the
         treatment of these injuries
Recommendations
  -	 Bone defects should be grafted
  -	 Early range of motion with weight bearing is allowed at 68
     weeks
Management
                                                                                    1
Management
                                                                                 Surgery
                                                                                 Orthopaedic
The goal of treatment is to restore an anatomic articular surface. This
can be difficult and sometimes impossible. Bone graft can be added to
metaphyseal defects to support the articular surface
  Type I:
        	 Long leg cast and leg elevation
  Type II
       	 ORIF of the fibula
       	 ORIF of the tibia. Once soft-tissue swelling subsides,
          minimally invasive open reduction and percutaneous
          techniques should be attempted.
  Type III
       	 ORIF of the fibular fracture to restore length
       	 ORIF of the tibia
       	 Closed reduction and external fixation of the tibia
       	 Combination of ORIF and external fixation of the tibia
  -	 If risk of over swelling
         	 Prevention or treatment of swelling by prolonged leg
            elevation
         	 Open surgical treatment should be deferred until the soft
            tissue condition improves (7-14 days)
         	 Weight bearing if there is radiologic evidence of bone
            healing
Classification (Weber)
  -	 Type A
       	 Avulsion of the fibula to the joint line
       	 Syndesmotic ligament intact
       	 Medial malleolus undamaged or fractured in a shear type
          pattern with the fracture line angulating in a proximal-
          medial direction from the corner of the morti:
       	 Oblique orOblique or spiral frala beginningfibula
          beginning at the level of the joint up to the shaft of the fibula.
       	 The syndesmotic ligament complex can be torn, but the
          large interosseous ligament is usually left intact so that no
          widening of the distal tibiofibular articulation occurs.
 Note:
 Fracture of the medial malleolus with complete disruption of the
 syndesmosis and a proximal fibular shaft fracture (Maisonneuves
 fracture) are also considered bimalleolar fractures on a functional
 basis.
Management
  Principles of initial treatment of ankle fractures
      	 Immediate closed reduction and splinting, with the joint
         held in the most normal position possible to prevent
         neurovascular compromise of the foot.
      	 An ankle joint should never be left in a dislocated position.
      	 If the fracture is open, the patient should be given
         appropriate intravenous antibiotics and taken to the
         operating room on an urgent basis for irrigation and
         debridement of the wound, fracture site, and ankle joint. The
         fracture should also be appropriately stabilized at this time.
                                                                                    1
ORIF is indicated if
                                                                                 Surgery
                                                                                 Orthopaedic
 -	 Failure to achieve or to maintain closed reduction
 -	 Displaced or unstable fractures
 -	 Fractures that requires abnormal foot positioning to maintain
    reduction
TRIMALLEOLAR FRACTURES
After the lateral and medial malleolar fractures have been internally
fixed, ligamentotaxis often will anatomically reduce the posterior
malleolar fragment. If this fragment represents less than 25% of the
articular surface of the tibial plafond and there is less that 2 mm of
displacement, internal fixation is not always required.
Management
  Extraarticular Fractures
       	 Fracture of the Anterior Process
              	 Treatment is by a non-weightbearing short leg cast
                 in neutral position for 4 weeks
         	 Fracture of the Tuberosity
               	 Isolated fractures of the calcaneal tuberosity are rare.
         	 Horizontal Fracture
              	 If the fragment is big enough, the application of the
                 skeletal traction can reduce it to the plantar-flexed
                 foot, and the pin is incorporated in a long leg cast
                 with the knee flexed at 30 degrees. For smaller
                 fragments or when closed reduction is unsuccessful,
                 ORIF with screws, wires or pullout sutures is
                 indicated.
         	 Vertical Fracture
               	 Because the minor medial fragment normally is
                  not widely displaced, plaster immobilization is not
                  required but may reduce pain. Limitation of weight
                  bearing with crutches is helpful.
         	 Fracture of the Medial Process:
               	 Conservative treatment with a well-molded short leg
                  walking cast is usually successful
         	 Fracture of the Body
               	 Marked displacement may benefit from closed
                  reduction to improve heel contour
         	 Fracture of the Sustentaculum
               	 Conservative treatment is usually successful. In the
                  rare instance of symptomatic non-union, careful
                  excision is indicated
         	 Intra-articular fractures
               	 Treatment of displaced intraarticular fractures
                  remains controversial
               	 Some surgeons still advise conservative treatment
               	 Other surgeons advocate early closed manipulation of
                  displaced intra-articular fractures, to at least partially
                  restore the external anatomic configuration of the
                  heel region. Internal fixation with percutaneous pins
                  (Essex-Lopresti technique) may be performed.
                                                                                    1
              	 Open reduction and internal fixation with pins,
                                                                                 Surgery
                                                                                 Orthopaedic
                 screws, or plates, with or without bone grafting, has
                 gained acceptance. The aim of ORIF is to restore
                 Bhlers angle and improve heel alignment through
                 stable fixation.
             	 Some authors advocate primary subtalar arthrodesis
                 for severely comminuted fractures.
Three fifths of the talus is covered with articular cartilage. The blood
supply enters the neck area and is tenuous. Fractures and dislocations
may disrupt this vascularization, causing delayed healing or avascular
necrosis.
Hawkins classification
Management
  Type 1
        	 Non-weightbearing below-knee cast for 23 months until
           clinical and radiologic signs of healing are present
  Type 2
        	 Closed reduction. In about 50% of cases, closed reduction
           is unsuccessful and open reduction and internal fixation
           with K-wires, pins, or screws is indicated
  Types 3 and 4
        	 Closed reduction is almost never successful; ORIF is the
           rule.
Hawkins classification
Management
Management
  -	 Stage 1, 2, and 3: Immobilization and restricted weight bearing.
  -	 Stage 4 and failed conservative treatment stage 1,2,3: Reduction
     and pinning or fixation with screws and excision with or without
     drilling
  -	 Arthroscopic management seems to give as good a result as
     arthrotomy, with fewer complications
  -	 Compression fractures of the talar dome are rare injuries. They
     cannot be reduced by closed methods. If open reduction, with
     or without bone grafting, is elected, prolonged protection from
     weight bearing is the best means of preventing collapse of the
     healing area.
                                                                                   1
1.3.4. Midfoot Fractures
                                                                                Surgery
                                                                                Orthopaedic
NAVICULAR FRACTURES
Classification (AO/OTA)
  -	 Type A: Extraarticular
  -	 Type B: Partial articular (talon-navicular joint involved)
  -	 Type C: Articular (talo-navicular & naviculo-cuneiform involved)
Management
  -	 Undisplaced / incomplete fractures: short leg cast (non-weight
     bearing for 4-6weeks)
  -	 Displaced /complete fractures: ORIF (lag screws) and short leg
     cast (non-weight bearing for 4-6weeks)
CUBOID FRACTURES
Classification (AO/OTA)
  -	 Type A: Extraarticular
  -	 Type B: Partial articular (calcaneo-cuboid or cubo-talsal joints
     involved)
  -	 Type C: Articular (calcaneo-cuboid and cubo-talsal joints involved)
Management
  -	 Undisplaced / minimal impacted fractures: short leg cast (non-
     weight bearing for 6weeks)
  -	 Displaced : ORIF (K-wire/lag screws) and short leg cast
METATARSAL FRACTURES
  Metatarsal Shaft Fractures
       	 Undisplaced fractures: short leg walking cast.
       	 Displaced fractures: closed reduction and short leg walking
          cast
       	 If significant angulation or intraarticular displacement
          persists: ORIF
  Metatarsal Neck & Head Fractures
       	 Traction (Chinese finger traps)
       	 Unstable reductions: percutaneous pinning under
          fluoroscopic imaging
Management
  -	 Short leg cast
  -	 In the rare event of a significant displaced intraarticular
     component, ORIF may be indicated.
Management
  -	 A weight-bearing removable immobilization
  -	 Spiral or oblique fracture of the proximal or middle phalanges of
     the lesser toes can be treated adequately by binding the involved
     toe to the adjacent uninjured toe (buddy taping)
  -	 Comminuted fractures of the distal phalanx are treated as soft-
     tissue injuries
Management
  -	 Undisplaced fractures: Hard-soled shoe or metatarsal bar
  -	 Displaced fractures: Immobilization in a walking boot or cast,
     with the toe strapped in flexion
  -	 If conservative modalities have been exhausted: THe last resort
     treatment is excision
  -	 Treatment of fractures in children: The treatment of the majority
     of fractures in children and adolescents will be conservative.
     Indications for surgical treatment of fractures in children
     include:
         	 Open fractures
         	 Polytrauma
         	 Patients with head injuries
         	 Femoral fractures in adolescents
         	 Femoral neck fractures
         	 Certain types of forearm fractures
         	 Certain types of physeal injuries
         	 Fractures associated with burns
                                                                                    1
1.4. Fractures in children
                                                                                 Surgery
                                                                                 Orthopaedic
1.4.1. Epiphyseal Fracture
The cartilage physeal plates are a region of low strength relative to the
surrounding bone and are susceptible to fracture in children.
Classification (Salter-Harris)
  -	 Type I: Transphyseal fracture involving the hypertrophic and
     calcified zones
  -	 Type II: Transphyseal fracture that exits the metaphysis
  -	 Type III: Transphyseal fracture that exits the epiphysis
  -	 Type IV: The fracture that traverses the epiphysis and the physis,
     exiting the metaphysis
  -	 Type V: Crush injuries to the physis
  Treatment
       	 Because physes are near joints and physeal fractures are
          common, children may suffer injuries to joint surfaces that
          require careful surgical repair and realignment. Thus, open
          reduction is more likely in fractures involving physes and
          joints than in other pediatric fractures.
Classification (Gartland)
  -	 Extension type
       	 Type I: Non displaced
       	 Type II: Displaced with intact posterior cortex, may be
          slightly angulated or rotated
       	 Type III: Complete displacement, posteromedial or
          posterolateral
  -	 Flexion type
        	 Type I: Non displaced
        	 Type II: Displaced with intact anterior cortex
        	 Type III: Complete displacement, usually anterolateral
Management
  -	 Stage I: Immobilization for 3 to 4 weeks
  -	 Stage II & III: Closed reduction and immobilization
Note:
 If the reduction is unable to be held percuteneous pins / screws may
 be placed
                                                                                    1
1.4.3. Radial Neck Fracture
                                                                                 Surgery
                                                                                 Orthopaedic
Classification (OBRIEN) based on degree of angulations
  -	 Type I: 00 - 300
  -	 Type II: 300 - 600
  -	 Type III: More than 600
Management
  -	 Type I: Immobilization for 7 to 10 days followed by early range
     of motion
  -	 Type II:
        	 Manipulative closed reduction and immobilization for 10
           to 14 days.
        	 Manipulative closed reduction and pinning
  -	 Type III: ORIF
PELVIC FRACTURE
Pelvic fractures in children are usually seen in conjunction with major
blunt trauma. Gross displacement is fairly uncommon and can usually
be treated symptomatically because the intact periosteum stabilizes the
large flat bones.
HIP FRACTURE
As in the adult, the fracture pattern may disrupt the blood supply of the
proximal femoral head and lead to avascular necrosis of the proximal
Management approach
  -	   Newborn to 2 years: Early spica cast
  -	   From 2 to 10 years of age:
  -	   Early spica cast
  -	   Skin traction (> 2 cm overriding)
  -	   From 10-15 years of age:
  -	   Undisplaced: Conservative treatment
  -	   Displaced: Operative treatment (flexible nails)
Causes
                                                                                     1
Diagnosis
                                                                                  Surgery
                                                                                  Orthopaedic
  -	 Clinical examination of the specific fracture should include the
     site of the fracture and severity of the fracture.
Investigations
  -	   FBC
  -	   Blood group and cross match
  -	   PT, PTT, U+E
  -	   Swab from the area
  -	   X-ray of the limb (Lateral and AP views)
Management
  Emergency management
       	 Emergency ATLS resuscitation
       	 Monitor level of consciousness (LOC)
       	 Analgesia preferably an Opoid Analgesic
       	 Antibiotics
       	 Remove gross contamination and apply a moist sterile
          dressing e.g. Betadine dressing
      	 Splint the limb
      	 Tetanus Toxoid Prophylaxis
       	 Urgent surgical debridement, washout and stabilization of
          the fracture
      	 Call the orthopaedic specialist after stabilizing the patient
          and emergency fracture care
  Definitive management
       	 Early administration of systemic antibiotics, timely surgical
           debridement, skeletal stabilization and delayed wound
           closure
             	 Grade 1: 1st generation cephalosporin
             	 Grade 2: 1st generation cephalosporin and/or  an
                aminoglycoside depending on the level of wound
                contamination
Classically, TBI has been divided into two distinct periods: primary
and secondary brain injury. The primary injury is the result of the
                                                                                    1
initial, mechanical forces, resulting in shearing and compression of
                                                                                 Surgery
                                                                                 Orthopaedic
neuronal, glial, and vascular tissue. The secondary injury is described
as the consequence of further physiological insults, such as ischaemia,
re-perfusion and hypoxia, to areas at risk in the brain in the period
after the initial injury.
Causes
  -	 Falls
  -	 Motor vehicle crashes
  -	 Assaults
Investigations
  -	 Head CT-Scan
  -	 Cervical spine x-ray or CT-scan
  -	 Chest x-ray
  -	 Abdominal US
  -	 Transcranian Doppler US
  -	 FBC, coagulation tests, Biochemistry
  -	 Arterial Blood Gas (ABG), central venous blood gas (internal
     jugular Saturation venous O2)
  -	 Any other investigation for associated injuries
Complications
  -	   Posttraumatic seizures
  -	   Hydrocephalus
  -	   Deep vein thrombosis
  -	   Spasticity
  -	   GI and GU complications
  -	   Gait abnormalities
  -	   Autonomic dysfunction syndrome
  -	   Diabetes insipidus
  -	   Brain herniation and death
Management
  Treatment of first choice
       	 Early detection and minimization of any secondary insults
       	 Cervical spine stabilization
       	 Avoid moving the patient if at all possible
       	 Secure and preserve the airway
       	 Maintain and support breathing
       	 Intubation and mechanical ventilation
       	 Maintain effective circulation with IV fluids with isotonic
          solutions
       	 Maintenance of adequate mean BP in order to sustain an
          adequate cerebral perfusion pressure (CPP) ; CPP=MAP-
          ICP (targeted CPP:70-110mmhg)
       	 Effective pain relief
       	 Arrest bleeding
       	 Regular evaluation of GCS and pupillary asymmetry and
          reaction to light
       	 Ensure Normoxemia, normoglycemia, normo or mild
          hypothermia,normonatremia and normocapnia (35-
          38mmhg)
       	 Head straight and elevated at 300C
       	 Prevention of seizures with Phenytoin 5mg/kg/24hrs or
          Phenobarbital 5mg/kg/24hrs Slow IV
  Surgical Treatment
       	 Surgical decompression or craniectomyare indicated in:
             	Open, depressed skull fracture
             	Subdural or epidural hematomas
             	Intraparenchymal hemorrhages or contusions
                resulting in significant mass effect or midline shift.
                Pre-operation considerations include associated
                injuries like intra-abdominal, orthopedic, spinal cord
                and other organ trauma
                                                                                     1
                  (thiopental 3-5mg/kg) or Etomidate 0.3 mg/kg,
                                                                                  Surgery
                                                                                  Orthopaedic
                  maintenance with Isoflurane or Sevoflurane, muscle
                  relaxants: Vecuronium 0.1 mg/kg or Pancuronium 0.1
                  mg/kg or Tracurium 0.5 mg/kg
          	 INTRAOPERATIVE MONITORING
                	 Monitors/Line Placement, standard monitors plus
                   intra-arterial BP monitor, ideally placed prior to
                   induction, CVP monitoring, ICP monitor may
                   be placed by neurosurgeons, Maintain CPP above
                   70mmHg, avoid increasing ICP, maintain mild
                   hypothermia, avoid hypoxemia & hypercarbia,
                   treat anemia, coagulopathy, volume resuscitate with
                   isotonic, glucose-free solutions or colloids and, blood
                   or blood products if indicated, avoid hyperglycemia
                   (keep glucose <150 mg/dL) and hypoglycemia.
         	 MANAGEMENT OF HYPOTENSION
              	 Use vasopressors (norepinephrine 0.01-0.1 g/kg/min
                 post-operative period, manage pain, sedation with
                 midazolam 5-15 mg/hour + Fentanyl 50-150 g/hour
                 may be required if patient is left intubated.
Investigations
  -	   X-rays of the chest, pelvic and C-spine
  -	   Abdominal US
  -	   Head CT-Scan if head Injury
  -	   Body scan
  -	   X-ray of affected limbs
  -	   FBC, Blood group and cross-match, coagulation tests
  -	   Chemistry (electrolytes, transaminases, CPK, Troponin)
Complications
  -	   Haemorrhage infection/ Sepsis
  -	   Multi organ failure
  -	   Deep venous thrombosis
  -	   Fat air embolism
Management
  Treatment of first choice
       	 Adult Assessment Procedure focusing on initial C-spine,
          ABCD and level of responsiveness (see ATLS)
       	 Spinal immobilization
       	 Airway protection and/or maintenance if appropriate
       	 Assess Vital Signs and GCS
  If hypotension
        	 Give IV fluids: Normal saline until you get a mean arterial
           pressure > 60 mmHgSplint Suspected fractures consider
           pelvic binding/ radiological embolization if available
        	 Control external hemorrhage
        	 Tension Pneumothorax: chest decompression
        	 Laparotomy if abdominal injuries
                                                                                    1
         	 Head injury protocol (if head injury)
                                                                                 Surgery
                                                                                 Orthopaedic
         	 Blood and/or blood components transfusion if needed
  Supportive treatment
       	 Dialysis in case of renal failure
       	 Mechanical ventilation in case of ALI/ARDS
       	 Inotropic drugs like dobutamine 5-20 g/kg/min in case of
          cardiogenic shock due to myocardial contusion
       	 NGT for enteral feeding
       	 Prevention of DVT with LMWH e.g. Enoxaparine 40mg
          SC/day (starting from day 5 if no contraindications)
1.7. Dislocations
Causes
  -	 Direct Trauma
       	 High Energy trauma
             	Road traffic accident
             	Fall from Heights
             	Sports injuries
             	Industrial injuries
  -	 Indirect Trauma
       	 Varus, Valgus and rotational stress
Investigations
  -	 X-Rays (Lateral view, Anteroposterior View)
  -	 CT Scan
  -	MRI
 Note:
   Associated clavicle, upper rib fractures and brachial plexus
   injuries are due to high energy trauma in this type
                                                                                      1
Investigations
                                                                                   Surgery
                                                                                   Orthopaedic
  -	 Antero-Posterior x-ray for both shoulders (comparison)
  -	 Stress x-ray of the affected shoulder (holding weight) in case of
     doubt
Complications
  -	 Type 1: Rest 7-10 Days with an Arm sling (refrain from full
     activity for 2 weeks)
  -	 Type 2: Use of Arm sling for 1-2 weeks (refrain from heavy
     activity for 6 weeks)
  -	 Type 3: Conservative Treatment (arm sling) or Surgical
     Treatment (surgical repair)
  -	 Type 4, Type 5 and Type 6: Open reduction and surgical Repair
     of the Coraco-Clavicular Ligament
Description
ANTERIOR DISLOCATIONS
 -	 Pain, tenderness and swelling of the affected shoulder
 -	 Arm of the affected shoulder is held in abduction and External
    Rotation
 -	 Decreased Range of motion
 -	 Loss of deltoid contour compared with contralateral side
 -	 Prominence of the Acromion and palpable head of the humerus
    anteriorly in the Axila
Note:
  Careful assessment of the neurovascular status. (Evaluate sensory
  and motor function of the musculocutaneous and radial nerves.
  Compare distal pulses on both extremities.)
Investigations
Complications
  -	 Recurrent dislocation
  -	 Soft tissue injuries (rotator cuff injury)
  -	 Vascular Injury- Axillary Artery (Rare: only in elderly patients
     with arthrosclerosis)
  -	 Nerve injury especially the Musculocuteneous and Axillary
     Nerve
  -	 Osseous lesions
  -	 Post traumatic osteoarthritis
Management
  Conservative (closed reduction)
       	 Analgesics and/or Sedation
       	 Always conservative for acute anterior shoulder
          dislocations
       	 Arm sling after closed reduction for 2-3 weeks (elderly
          patients) and 6 weeks for (young patients)
  Surgical
       	 Indication: Chronic dislocation, soft tissue interposition,
           fracture dislocation
POSTERIOR DISLOCATION
Investigations
Complications
  -	 Recurrent dislocation
  -	 Nerve Injury especially the Axillary nerve
                                                                                     1
  -	 Osseous lesions
                                                                                  Surgery
                                                                                  Orthopaedic
  -	 Post traumatic osteoarthritis
Management
  Conservative (Closed reduction)
       	 Analgesics and/or sedation
       	 Always conservative for acute posterior shoulder
          dislocations
       	 Arm sling after closed reduction for 2-3 weeks (elderly
          patients) and 6 weeks for (young patients)
  Surgical
       	 Indication: Chronic dislocation, soft tissue interposition,
           fracture dislocation
Recommendations
Description
Classification
POSTERIOR DISLOCATIONS
Investigations
Complications
Management
  Surgical
       	 Indication: Chronic dislocation, soft tissue and/or bony
           entrapment, fracture dislocation, recurrent instability.
Recommendations
Description
                                                                                     1
Investigation
                                                                                  Surgery
                                                                                  Orthopaedic
  -	 X-ray Antero posterior of the pelvis
  -	 Oblique radiographic projections (Judet views)
  -	 CT Scan (Preferably post reduction)
POSTERIOR HIP DISLOCATION
Classification
  -	 Posterior dislocation is the most common and accounts for 90%
     of all hip dislocations.
  -	 Classification of Posterior dislocations (Thompson and Epstein
     Classification)
        	 Type 1- Simple dislocation with or without any significant
            posterior wall fragment
        	 Type 2- Dislocation associated with a single large posterior
            wall fragment
        	 Type 3- Dislocation with a comminuted posterior wall fragment
        	 Type 4- Dislocation with fracture of the acetabular floor
        	 Type 5  Dislocation with fracture of the femoral head
Note:
 Full trauma survey is critical due to the high energy nature of the
 injury.
  -	 Severe pain
  -	 Abduction flexion and external rotation of the affected limb
  -	 Decreased motion of the lower extremity on the affected side
  -	   Neurovascular injury
  -	   Thromboembolism
  -	   Avascular osteonecrosis
  -	   Post traumatic osteoarthritis
  -	   Recurrent dislocations
  -	   Heterotopic ossifications
  Conservative treatment
       	 Closed reduction under anesthesia
       	 Skin or skeletal traction (2-3 weeks)
  Open reduction
       	 Indications for open reduction
            	 Failure of closed reduction
            	 Non concentric reduction
            	 Fracture of the acetabulum or femur head that
               requires either excision or ORIF
            	 Ipsilateral femoral neck fracture
Causes
                                                                                   1
Signs and Symptoms
                                                                                Surgery
                                                                                Orthopaedic
  -	 Severe pain
  -	 Extreme swelling and gross knee derformity with or without
     neurovascular compromise
Investigations
Complications
  -	 Neurovascular
  -	 Ligamentous instability
  -	 Stiffness (due to prolonged immobilization and extend of soft
     tissue injury)
Classification
Management
  Conservative
       	 Immediate closed reduction and immobilization at 20-30o
          of flexion for 6 weeks
       	 Range of motion/exercise should be instituted after
          adequate soft tissue healing 6-12 weeks
  Surgical
        	 Indications
             	 Unsuccessful closed reduction
             	 Open injuries
             	 Vascular injuries
             	 Residual soft tissue interposition
Recommendations
Causes
  -	   Physiological laxity
  -	   Direct trauma to the patella
  -	   Connective tissue disease (Marfan Syndrome)
  -	   Congenital abnormality of the patella and trochlea
  -	   Hypoplasia of the Vastus Medialis muscle
  -	   Hypertrophy of the lateral retinacular
                                                                                     1
Signs and symptoms
                                                                                  Surgery
                                                                                  Orthopaedic
  -	   Pain focused around the knee joint
  -	   Inability to flex knee
  -	   Hemarthrosis
  -	   Swelling with tenderness of the knee
  -	   Palpated displaced patella
Investigation
Complications
  -	 Recurrent dislocation
  -	 Re-dislocation
  -	 Patella-femoral Arthritis
Management
  Conservative
       	 Closed reduction with cylinder casting for 2- 3 weeks
       	 Isometric quadriceps exercises after removal of the cast
  Surgery
       	 Recurrent episodes require operative repair
Pathophysiology
Causes
  -	 Staphylococcus Aureus
  -	 Streptococcus
  -	 Gram negative bacteria
Investigations
                                                                                     1
  -	 urethral, cervical, pharyngeal and rectal swabs
                                                                                  Surgery
                                                                                  Orthopaedic
  -	 Synovial fluid analysis: gram stain, culture, cell counts, crystal
     analysis
  -	 X-ray of the joint
       	 Often normal initially
       	 Soft tissue swelling around the joint, widening of the joint
           space, displacement of tissue planes
       	 Bony erosions and joint space narrowing, sclerosis, and
           patchy demineralization all in later stages
Complications
  -	   Septicemia
  -	   Dislocations
  -	   Growth plate damage in children
  -	   Osteomyelitis
  -	   Degenerative arthritis
  -	   Avascularis necrosis in hip and shoulder
Management
                                                                                      1
1.8.2. Acute Osteomyelitis
                                                                                   Surgery
                                                                                   Orthopaedic
Definition: Osteomyelitis is a bone infection
Cause/Etiology
- Bacterial
Pathogenesis
  -	 Inflammation
       	 Acute inflammatory reaction with vascular bacterial
          congestion
       	 Rise in intra-osseous pressure causing intense pain
  -	 Suppuration
       	 At 2-3 days pus forms within the bone and forces its way
          down the haversian canals to the surface where it forms a
          sub-periosteal abscess
       	 The pus can spread from here back into the bone, into an
          adjacent joint or into the soft tissues (where there is an
          intra-articular physis)
       	 Vertebral infection can spread through the end plate, disc
          and into the next vertebral body
  -	 Necrosis
      	 At 7 days, rising pressure, vascular stasis, infective
         thrombosis and periosteal stripping compromise the blood
         supply to the bone resulting in bone death resulting in a
         sequestrum
      	 New bone formation
      	 At 10-14 days this forms from the deep surface of the
         stripped periosteum forming the involucrum
  -	 Resolution
       	 With release of the pressure and appropriate antibiotics
          healing can occur
       	 There may be permanent deformity
       	 Unpublished work (quoted in Dee) shows that
          experimentally bacteria injected intravenously will settle in
          the metaphyses of bone preferentially
Note:
 -	 In 10% of cases there is more than one site of infection
 
Signs and Symptoms
       -	 Children (invariably)
            	 Pain, malaise, fever
            	 Limp or not weight bearing
       -	 Infants
             	 Failure to thrive, drowsiness, irritable
       -	 Adults
            	 The most common site is long bones
            	 Local erythema, swelling and tenderness indicates that the
               pus has broken through the periosteum
Investigations
       -	 FBC: Often leucocytosis with a left shift
       -	 ESR and CRP
       -	 Blood cultures
                                                                                     1
  -	 X-ray of the joint
                                                                                  Surgery
                                                                                  Orthopaedic
       	 Often normal initially
       	 Soft tissue swelling around the joint, widening of the joint
           space, displacement of tissue planes
       	 Bony erosions and joint space narrowing, sclerosis, and
           patchy demineralization all in later stages
- Ultrasonography
Complications
Management
  Non Operative
      	 ANTIBIOTIC ADMINISTRATION:
           	 It is recommended to start empiric treatment with a
               regimen that caters for S.aureus as the culture results
               are awaited
           	 Empiric regimen
      	 IV CLOXACILLIN and A 3RD GENERATION
         CEPALOSPORIN (e.g. ceftriazone)
                                  OR
      	 IV OXACILLIN can be used in the place of cloxacillin with
         the 3rd generation cephalosporin
           	 Culture results to guide definitive antibiotherapy
           	 The change to oral medication will depend on the
               clinical response i.e. fevers ceasing and decreasing
               CRP and ESR, with the generally accepted course
               being of 1week IV treatment then a change to oral
               medication
           	 The recommended minimal duration of drug therapy
               is 6 weeks
  Operative
      	 Periosteal abscess should be managed surgically.
  -	   Pain
  -	   Swelling/oedema
  -	   Often draining sinus
  -	   Sometimes deformity
Investigations
  -	   FBC
  -	   ESR and CRP
  -	   Blood cultures
  -	   Tissue culture and sensitivity
  -	   X-ray (Anteroposterior and lateral views)
  -	   CT Scan
  -	   MRI
  -	   Scintigraphy
Complications
Management
                                                                                    1
1.9. Hand Surgery
                                                                                 Surgery
                                                                                 Orthopaedic
1.9.1. Fracture of Wrist Bones
Description
  - 	 Carpal/wrist bones are in 2 rows:
        	 Awrist fractureis a break in one or more of the bones in
           thewrist.
        	 The proximal row which is made from radial to ulna sides
           of the scaphoid, lunate, triquetrum and pisciform bones.
        	 The distal row which is made from radial to ulna of the
           trapezium, trapezoid, capitate and hamate bones.
Causes
Classification
Investigations
Complications
  -	 Bone Necrosis
  -	 Pseudo Arthrosis
Management
  Conservative treatment
       	 Short arm casting for 12 weeks
       	 Physiotherapy after removal of casting
  Surgical
       	 Open reduction and internal fixation (ORIF)  bone
           grafting associated with short arm casting for 8 weeks
       	 Physiotherapy after removal of casting
Recommendations
                                                                                     1
1.9.3. Perilunate Dislocation and Perilunate Fracture Dislocation
                                                                                  Surgery
                                                                                  Orthopaedic
Definition: Perilunate dislocation and Perilunate fracture dislocation
are injuries that involve traumatic rupture of the Radio-Scaphal Capitate
(RSC) ligament, the scapholunate interosseous and lunotriquetral
interosseous ligament.
Investigations
Complications
Management
Recommendation
Investigations
Management
  Conservative: Short arm casting for 8 weeks
  Surgical: ORIF with short arm casting.
  Physiotherapy after removal of casting
Causes
  -	   Falls
  -	   Blunt injuries
  -	   Penetrating injuries
  -	   Sport contact injuries
                                                                                     1
Signs and Symptoms
                                                                                  Surgery
                                                                                  Orthopaedic
  -	   Pain
  -	   Swelling of the hand, hematoma and bruising overlying skin
  -	   Decreased range of motion of the fingers
  -	   Shortening of fingers involved
  -	   Rotation of finger
  -	   Angulation
Investigation
  -	 Plain x-ray (Antero-posterial and oblique views)
Management
  Conservative
       	 Closed reduction and volar splinting in functional position
          for 6 weeks
       	 Physiotherapy after removing the splint
  Surgical
       	 Closed reduction and percutaneous pin fixation
       	 Open reduction and internal fixation
Recommendations
  -	 Keep the hand elevated to decrease pain and swelling
  -	 Make sure the finger is not rotated after fixation
Description
Causes
  -	 Fall with axial loading through the thumb metacarpal
  -	 Direct blow of the thumb metacarpal
  -	 Injury involving forced abduction of the thumb
Investigations
  -	 Plain x-ray (Antero-posterial and oblique views)	
Management
  Surgical
       	 If the Bennetts fragment is less than 15-20% of the
           articular surface: Closed reduction and percutaneous pin
           fixation followed by a thumb spica splint for 4-6 weeks.
       	 Open reduction and internal fixation. (If the Bennetts
           fragment is greater than 20% or articular step off after pin
           fixation is greater than 1 mm)
       	 For Rolandos fracture: Always do Open reduction and
           internal fixation (ORIF)
Recommendations
  -	 Always refer Bennetts or Rolandos fractures to the orthopedic
     surgeons after immobilization in a splint.
Causes
  -	 Direct blow
  -	 After punching a person or object such as a wall
Investigation
  -	 Plain x-ray (Antero-posterial and oblique views)	
Management
  -	 If angulation is less than 40%: Closed reduction and splint
  -	 If angulation is more than 40% : Closed reduction and
     percuteneous pin fixation or open reduction and ORIF (Open
     reduction and Internal Fixation)
                                                                                     1
Recommendation
                                                                                  Surgery
                                                                                  Orthopaedic
  -	 Check for rotation deformity after fixation
Causes
  -	   Falls
  -	   Direct blows
  -	   Sport contact injuries
  -	   Machinery injuries
Investigation
  -	 Plain x-ray (AP, lateral and oblique views)
Complication
  -	 Digital neuro-vascular bundle injuries
Management
  Conservative (Exra-articular fractures)
       	 Closed reduction,
            	 if stable do buddy strapping for 4 weeks
            	 If reduction not stable then do surgery
            	 Surgical (Unstable Fractures and/or Intra-articular
                fractures)
       	 Closed reduction with per-cutaneous pin fixation
           Or
       	 Open reduction and internal fixation with plates and
          screws
Recommendation
  -	 Always check sensation and perfusion of the fingers before and
     after treatment
Causes
  -	 Crush injuries (from doors mostly in children)
  -	 Work related trauma
  -	 Falls
Investigation
  -	 Plain x-ray (AP and lateral views)
Complication
  -	 Traumatic amputation of the fingertip
Management
  -	 If fracture is associated with nail bed laceration, repairing the
     laceration will reduce the fracture. Then stabilize with a Zimmer
     splint for 4 weeks.
  -	 Otherwise do fixation with an axial per-cutaneous pin if the
     distal fragment is big enough.
                                                                                     1
1.9.10. Dislocations of the Hand Joints
                                                                                  Surgery
                                                                                  Orthopaedic
Definition: A dislocation is a misalignment of the bones forming a
joint. Metacarpophalangeal joints and interpharlangeal are the most
commonly involved.
Causes
  -	 Falls
  -	 Sport injuries
Investigation
  -	 Plain x-ray (AP, lateral and/or oblique views)
Complication
  -	 Nerve injuries
Management
  Conservative
       	 Relocate under nerve block or general anesthesia. If
          relocation is difficult under those circumstances do an
          open reduction
       	 Splinting in functional position for 4 weeks and then
          physiotherapy
  Surgical
       	 Sometime the volar plate or tendons can be entrapped into
           the joint and that is why it may be impossible to do a closed
           reduction.
Recommendation
  -	 Refer to orthopedic surgeon or hand surgeon any dislocation
     that cant be relocated conservatively.
1.9.11. Burns
1.9.12. Infections
PARONYCHIA ABCESS
Definition: It is the infection of the soft tissue fold around the nail. It
is the most common infection of the hand.
Causes
  -	 Splinters
  -	 Manicure instruments
  -	 Nail biting
Investigations
  -	 Plain x-ray to exclude bone involvement in late or advanced
     presentations
  -	 Microbiology culture and sensitivity of pus and/or necrotic tissue
                                                                                      1
Complications
                                                                                   Surgery
                                                                                   Orthopaedic
  -	 Pulp abscess
  -	 Bone involvement
  -	 Extensive soft tissue necrosis
Management
  Conservative
        	 For early presentations: warm soaks and systemic antibiotics
  Surgical
        	 Abscess drainage
        	 Debridement of necrotic tissues
        	 Systemic antibiotics for 6 weeks if the bone is involved
Causes
  -	 Splinters
  -	 Thorns
Investigations
  -	 Plain x-ray to exclude bone involvement
  -	 Microbiology culture and sensitivity of pus and/or necrotic tissue
Complications
  -	 Bone involvement
  -	 Extensive soft tissue necrosis
Management
  -	 Lateral incision and drainage
  -	 Systemic antibiotics
TENOSYNOVITIS
Causes
  -	 Wound bite
  -	 Any other penetrating injury
Investigations
  -	 Plain x-ray to exclude bone involvement
  -	 Microbiology culture and sensitivity of pus and/or necrotic tissue
Complications
  -	 Proximal extension of the infection to the hand and forearm
  -	 Extensive soft tissue destruction
  -	 Bone involvement
Management
  -	 Incision and drainage of the tendon sheath (refer to text books
     for description of proper technique)
  -	 Systemic antibiotics
Cause
  -	 Human bites
                                                                                   1
Investigations
                                                                                Surgery
                                                                                Orthopaedic
  -	 Plain x-ray
  -	 Microbiology culture and sensitivity of pus and/or necrotic tissue
Complications
  -	 Complete destruction of the joint
  -	 Extensive soft tissue destruction
Management
  -	 Opening of the joint and adequate debridement (as many as
     required)
  -	 Systemic antibiotics
Causes
  -	 Penetrating injuries
  -	 Retained foreign bodies
Investigations
  -	 FBC
  -	 MCS (Microbiology culture and sensitivity) of pus and/or
     necrotic tissue
  -	 US
  -	 X-ray
Complications
  -	 Extension of the infection into the forearm
  -	 Extensive soft tissue destruction
  -	 Frozen hand
Management
  -	 Adequate incision and drainage plus debridement of necrotic
     tissue
  -	 Systemic antibiotics
  -	 Splinting
  -	 Early mobilization
Causes
  -	   Penetrating injuries
  -	   Traumatic forced extensions
  -	   Pathologic ruptures
  -	   (Note): Flexor and Extensor tendon injuries will be discussed
       seperately
Types
                                   :
FLEXOR TENDON INJURIES Laceration or rupture of tendons that
flex the wrists and fingers
                                                                                     1
  Specific in Extensor Tendor Injuries
                                                                                  Surgery
                                                                                  Orthopaedic
        	 Loss of active extension of the wrist or fingers
        	 Presence of laceration on the dorsal aspect of the forearm,
            wrist, hand or fingers
Investigations
  -	 Plain x-ray to exclude associated fractures
  -	 FBC
Management
  -	 Before transferring the patient to a hand or orthopedic surgeon
     do the following:
       	 Saline wash of the wound
       	 Removal of foreign bodies
       	 Dress the wound and put the hand in a volar splint
Complications
  -	   Arterial injuries
  -	   Nerve injuries
  -	   Infections
  -	   Rupture of repaired tendon
  -	   Adhesions
  -	   Late flexion deformity
Causes
  -	 Penetrating injuries
  -	 Compression neuropathies
  -	   Paralysis
  -	   High radial palsy: loss of extension of wrist and fingers
  -	   Low radial palsy: extension of wrist is preserved
  -	   High median palsy:
         	 Paralysis of long flexors of the thumb, index and middle
             finger
         	 Loss of thumb opposition
         	 Paralysis of pronator teres
  -	 High ulna palsy: It is similar to low ulna palsy except that there is
     no clawing deformity
Investigations
  -	 FBC
  -	 Plain x-ray
  -	 EMG (Electromyography)
Management
  -	 For non penetrating injuries, follow up patients for 3 months to
     rule out neuropraxia which will recover spontaneously.
  -	 For penetrating injuries, if nerve injury is suspected, refer the
     patient to a unit that can explore the wound and repair damages.
Complications
  -	   Associated arterial injuries
  -	   Paralysis
  -	   Neuromas
  -	   Hyper or hyposensitivity
                                                                                     1
1.9.15. Vessel Injuries
                                                                                  Surgery
                                                                                  Orthopaedic
Definition: Laceration to the arterial supply of the hand or fingers.
Causes
  -	 Penetrating injuries
  -	 Fractures
Investigations
  -	 FBC
  -	 Plain x-ray
Management
  -	 What to do in case of profuse arterial bleeding:
      	 Follow ATLS protocol
      	 Elevate the hand
      	 Put a tourniquet proximal to the laceration
      	 Explore the wound or put a compressive dressing just on
          the spot that is bleeding just enough to control bleeding
      	 Remove the tourniquet
      	 Take the patient to theater for selective ligation of the
          artery or its repair
          If Compartment Syndrome is suspected, do compartment
          release with appropriate fasciotomy.
Complications
  -	 Associated nerve injuries
  -	 Compartment Syndrome
  -	 Loss of hand or finger (Gangrene)
Causes
  -	   Burn
  -	   Trauma
  -	   Tumor excisions
  -	   Debridement
Management
  -	 If the wound can be closed without compromising the function
     of the hand or the anatomy of the hand, do a primary closure
  -	 If a primary closure is not feasible and there is no underlying
     vital structures exposed, do a skin graft
  -	 If underlying structures are exposed, cover with a flap
  -	 If underlying structures are involved, repair them and cover with
     a flap
Complications
  -	 Scar contractures
  -	 Damage of vital structures
                                                                           Neurosurgery
junction to the sacrococcygeal region. It may be complete or partial.
Cervical cord injuries are divided into two namely high cervical and
low cervical injuries.
High cervical injuries are from C3 and above and are associated with
high mortality rates due to the phrenic nerve being cut off (C3, 4 and 5
that results in respiratory failure)
Causes
  -	   Trauma
  -	   Tumors
  -	   Infections
  -	   Vascular conditions
  Complete
      	 High cervical injury; most of the patients will die at the
          scene of the accident because of respiratory failure
            	 Gasping for air
            	 Urinary retention
            	 Reduced GIT function
  Partial
        	 Partial Cord injuries are composed of the following
           syndromes
             	 Central Cord Syndrome: greater motor deficit in
                 upper limbs than lower limbs
             	 Brown Sequard (Cord hemisection) Syndrome:
                 motor paralysis and loss of proprioception and
                 vibratory sense ipslateral to the lesion with loss of
                 pain and temperature sensation contralateral to the
                 lesion 1 or 2 segments below
             	 Anterior Cord Syndrome: loss of motor function
                 with preservation of proprioception and vibratory
                 sensation
             	 Posterior Cord Syndrome: loss of proprioception
                 and vibratory sensation with preservation of motor
                 function
Investigations
  -	 FBC, CRP and ESR etc. when suspecting infection
  -	 X-rays and CT scan may show the bony cause of spinal cord
     injury
  -	 Myelography with or without CT scan, indicated for people that
     have contra indication for MRI
  -	 Investigation of choice is MRI
Management
  -	 For spinal trauma manage according to ATLS (Adult Trauma Life
     Support)
  -	 Put cervical collar
  -	 Hard board for thoracic and lumber suspected injuries (Prevent
     pressure sores)
  -	 For blunt trauma give Methyl prednisolone 30mg/kg IV for
     30min and rest for 30min give 5mg/kg/hr 23 hours for those
     seen within first 5 hours of injury and for 48 hours for those seen
     between 5 - 8 hours of injury
  -	 After making diagnosis treat accordingly
Complications
  -	   Pressure sores
  -	   Respiratory Tract Infections                                          2
  -	   Urinary Tract Infections
                                                                            Neurosurgery
  -	   DVT
  -	   Pulmonary embolus
Recommendation
  -	 Complications are best managed by anticipatory preventive
     measures.
Causes
  -	   Motor accidents
  -	   Fall from height
  -	   Sports injuries
  -	   Projectiles
  -	 Thoracic
       	 Upper
       	 Middle
       	 Thoraco lumber
  -	 Lumber
       	 Wedge compression fractures
       	 Burst fractures
       	 Fracture dislocations
       	 Seatbelt fractures
C1 Fractures
There are three types of C1 fractures, types I to III, the most common
is type II (Jefferson)
C1 - JEFFERSON
Cause
  -	 Loading force directly over the head (in neutral position)
Investigations
  -	 X-ray of C spine
  -	 C T scan (best choice)
  -	 MRI
Management
  -	 Analgesia
  -	 Hard collar or SOMI brace (Sternal Occipital Mandibular
     immobilization)
  -	 Surgical intervention indicated when there is disruption of
     transverse ligament
C2 - FRACTURES
ODONTOID FRACTURES
 -	 Type 1: fracture through the tip
 -	 Type 2: fracture through the base of odontoid
 -	 Type 3: involves both odontoid and body of C2
Causes
  -	   Motor accidents
  -	   Fall from height
  -	   Sports injuries
  -	   Projectiles
                                                                                Neurosurgery
  -	   Paraspinal muscle spasm
  -	   Reduced range of motion of the neck
  -	   Tenderness to palpation over the upper cervical spine
  -	   Tendency to support the head with the hands
  -	   Paraesthesias in upper limbs
Investigations
  -	 C  x-ray with open mouth views
  -	 CT scan
Management
  -	 Type1: The most common is immobilization with SOMI brace
     or hard collar. Sometimes needs surgery because of associated
     ligamentous injury
  -	 Type 2: If there is displacement of more than 4mm surgery is
     needed
  -	 Type 3: Treated by immobilization with SOMI brace or hard
     collar for 6 -12 weeks
HANGERMANS FRACTURES
Description: Bilateral fracture through the pars interarticularis with
traumatic sublaxation on C2 and C3, most of them are stable with no
neurological deficits. It has three types which are: type1, type2, type 3
(Levine classification), type 1 is stable; types 2 and 3 are unstable.
Causes
  -	   Motor accidents
  -	   Fall from height
  -	   Sports injuries
  -	   Projectiles
Investigations
  -	 X-rays
  -	 CT scan with CTA (CT angiography)
  -	 MRI/MRA (MR angiography)
Management
  -	 SOMI brace or hard collar for 8- 14 weeks
  -	 For Type 2 may require closed reduction with external
     immobilization
  -	 Type 3 requires ORIF
Types
  -	 Unifacet sublaxation (Jumped facet)
  -	 Bifacet sublaxation
UNIFACET SUBLAXATION
Cause
  -	 Flexion and rotation of the neck
Investigations
  -	 C  spine x-rays
       	 AP view spinous process above sublaxation they rotate to
           the same side of the jumped facet
       	 Lateral view shows bow tie sign (visualization of left and
           right facet joint instead of usual superimposed position
       	 Oblique view may demonstrate jumped facet blocking
           neuro foramen
Management
  -	 Initial treatment may be open or closed reduction.
BIFACET SUBLAXATION
                                                                            Neurosurgery
87% complete quadriplegia.
Investigations
  -	 C spine x-ray (lateral view show a vertebral body over the
     adjacent one)
  -	 CT scan
  -	 MRI to rule out prolapsed disc
Management
  -	 Closed reduction by putting patient on prolonged tongs traction
  -	 ORIF
Causes
  -	   Motor accidents
  -	   Fall from height
  -	   Sports injuries
  -	   Projectiles
Investigation
  -	 MRI is the investigation of choice
Management
  -	 Commonly supportive
  -	 Surgical intervention has shown no improved outcome
Causes
  -	   Motor accidents
  -	   Fall from height
  -	   Sports injuries
  -	   Projectiles
Investigations
  -	 Thoracic x-rays
  -	 CT thoracic spine
  -	 MRI
Management
  -	 Initial assessment and management according to ATLS
  -	 Definitive treatment in specialized centres
                                                                              Neurosurgery
rigid thoracic spine and mobile lumbar spine. It is between T10 to L2.
This is among the most commonly susceptible regions to fractures.
COMPRESSION FRACTURES
Cause
  -	 Flexion injury to thoraco lumbar region
Investigations
  -	 Plain thoracolumbar x-rays ( AP &Lateral Views)
  -	 CT Scan
Management
Recommendations
  -	 Bed rest
  -	 Analgesia
  -	 TLSO ( Thoracolumbar sacral orthosis)
BURST FRACTURES
Causes
  -	   Motor accidents
  -	   Fall from height
  -	   Sports injuries
  -	   Projectiles
Investigations
  -	 X-rays
       	 Lateral x-rays show; cortical fracture of posterior VB
       	 retropulsion of bone fragments into canal
       	 AP View show increase in interpeducular distance,
          laminae fractures, spraying of facet joints
  -	 CT scan
  -	 MRI
Management
  -	 Manage according to ATLS protocol
  -	 Specialized surgical intervention
SEATBELT FRACTURES
Causes
                                                                                2
  -	   Motor accidents
                                                                               Neurosurgery
  -	   Seatbelt injuries
  -	   Fall from height
  -	   Sports injuries
  -	   Projectiles
Investigations
  -	 X-rays
  -	 CT scan
  -	MRI
Management
  -	 Manage according to ATLS
  -	 TLSO in extension for patients with no neurological deficit
  -	 Specialized surgical intervention
FRACTURE DISLOCATION
Causes
  -	   Fall from height
  -	   Motor accidents
  -	   Sports injuries
  -	   Projectiles
  -	   Severe pain
  -	   Tenderness to palpation
  -	   May have abdominal injuries
  -	   Neurological deficit
Investigations
  -	 X-rays
  -	 CT scan
  -	 MRI
Management
Causes
  -	 Sphincter disturbance
  -	 Saddle anesthesia
  -	 Significant motor weakness (usually involves more than a single
     nerve root if not treated may progress to paraplegia)
  -	 Bilateral absence of Achilles reflex
  -	 Low back pain and/or Sciatica usually bilateral
  -	 Sexual dysfunction
Investigations
  -	   Infection screening
  -	   X-ray
  -	   CT scan
  -	   MRI
Management                                                                  2
  -	 Surgical intervention in specialized centers in case of
                                                                           Neurosurgery
     compression, which must be performed within 24 hours
  -	 Conservative management in case of inflammatory and ischemic
     neuropathies
Complications
  -	   Paraplegia
  -	   Persistent sphincter dysfunction
  -	   Pressure sores
  -	   Urinary infection
  -	   DVT
Risk Factors
  -	   Age ( > 55yrs)
  -	   Gender common in females
  -	   Previous stroke
  -	   Alcohol consumption
  -	   Drug abuse
  -	   Cigarette smoking
  -	   Liver dysfunction
Causes
  -	   Chronic poorly treated hypertension
  -	   Amyloid angiopathy
  -	   Ischaemic transformation
  -	   Rupture of an aneurysm
  -	   AVM (arterio Venous malformation)
  -	   Coagulopathies
  -	   Tumors
  -	   Idiopathic
Causes
  -	 Hypertension
  -	 Trauma
Investigations
  -	   Coagulation screen (LFTs, PI/PTT or INR etc)
  -	   RFTs
  -	   Glycemia
  -	   ECG
  -	   CT scan without contrast
  -	   CT angiography in suscipicious cases ( AVM, aneurysm)
  -	   MRI (Not necessary in acute phase)
Management
  -	 Manage according to ACLS (Advanced Cardiac Life Support)
  -	 Manage specific to cause:
       	 Anuarysm (see Sub Arachnoid haemorrhage (SAH))
       	 AVM; do clipping or embolization or both
  Non surgical
       	 Minimally symptomatic lesions ( GSC >10)
       	 Situations with little chance of good outcome such as poor
          prognostic factors such as: renal failure, heart failure, poor
          neurological dysfunction etc.                                       2
       	 Severe coagulopathies
                                                                             Neurosurgery
       	 Basal ganglia or thalamic hemorrhage
  Surgical
        	 Lesion with marked mass effect, oedema, midline shift
        	 Lesions where symptoms appear to be due to increases ICP
        	 Volume of hematoma (Types minor < or = 10mls,
           moderate 10-30mls, severe > 30mls) surgery is indicated
           for moderate volumes
        	 Cerebellar hematomas surgery is indicated for hematomas
           > or = 3cm in widest diameter
        	 Failure of medical management
        	 Rapid deterioration regardless of hematoma location and size
        	 Favorable location e.g. lobar, cerebellar, external capsule
           and non dominant hemisphere
        	 Age less than 50yrs
        	 Early intervention (less than 24 hours)
Causes/Risk factors
  -	 Hypertension
  -	 Smoking
  -	 Excessive alcohol consumption
Investigations
     -	 Coagulopathy screen
     -	 CT Scan without contrast
     -	 CTA
Management
Management is based on grade of patient
 II             13-14               Absent
 III            13-14               Present
 IV             7-12                Present or absent
 V              <7                  Present or absent
  General measures
       	 Fluids additional 3l to the usual maintenance
       	 Adequate analgesia
       	 Elevate head to 300
       	 Quiet rooms and dim light
       	 Anticonvulsants
       	 Stool softeners
       	 Nimodipine 60mg Per Os every 4 hours for 21days or
          when aneurysm is clipped
       	 Aneurysm clipping or coiling (specific measure)
Complications
     -	 Vasospasms occurs between day 3  14
     -	 Treated with hydration and Nimodipine
           	 Hydrocephalus which can occur immediately or after
Causes                                                                        2
  -	 Hematogenous spread
                                                                             Neurosurgery
  -	 Contagious spread
Investigations
  -	 Infection screen
  -	 CT scan with contrast
Complications
  -	 Seizures
  -	 Permanent neurological deficit
Management
Management may be medical alone or medical with surgical drainage/
surgical excision
  Medical management
       	 Fluid resuscitation
       	 Anticonvulsants
       	 Antibiotics
Note:
 ICU admission may be necessary depending on GSC
Definition/Description
Causes
  -	 Hematogenous spread
  -	 Contagious spread
  -	 Direct inoculation
Investigations
  -	 Infection screen
  -	 CT scan with contrast
Complications
  -	 Seizures
  -	 Permanent neurological deficit
Management
  Medical management
       	 Fluid resuscitation
       	 Anticonvulsants
       	 Antibiotics
       	 ICU admission may be necessary depending on GSC
Mode of transmission
                                                                              2
  -	 Water and food contaminated with eggs
                                                                             Neurosurgery
  -	 Fecal oral
  -	 Auto infection
  -	 Seizures
        	 Signs of Raised ICP
        	 Focal neurological deficits
        	 Subcutaneous nodules
Investigations
Management
Causes
  -	   Congenital abnormality
  -	   Intraventricular hemorrhage
  -	   Infection
  -	   Head trauma
  -	   Brain tumor
Investigations
Complications
  -	   Permanent blindness
  -	   Permanent psychomotor disability
  -	   Shunt complication (malfunction)
  -	   Infection
Management
2.5. Myelomeningocele
Definition: Congenital defect in vertebral arches with cystic dilatation
of meninges and structural or functional abnormality of spinal cord or
cauda equina.
Risk factors
                                                                               2
  -	 Low folate during female reproductive age
                                                                              Neurosurgery
  -	Obesity
  -	Smoking
  -	 Alcohol use
  -	Anticonvulsants
  -	 Febrile illness, heat exposure, hot tub and sauna during first
     trimester
  -	 Genetic
  -	 Young age
Investigations
  Prenatal
       	 Amniocentesis
       	 Ultrasound
  Postnatal
       	 CT scan
       	 MRI
Management
  -	 Early closure of myelomeningocele defect by a trained surgeon
  -	 Infection prophlaxis with ceftriaxone or cetaxime and
     gentamycin immediately for 1 week
  -	 Covering of spinal defect with a sterile saline soaked gauze which
     can be changed as needed
  -	 Monitor head circumference and anterior fontanel for possible
     development of hydrocephalus
Complications
  -	   Permanent neurological deficit
  -	   Pressure sores
  -	   Urinary tract infection
  -	   Meningitis
  -	   Ventriculitis
  -	   Hydrocephalus
It can also be classified by severity into mild, moderate and sever head
trauma depending on the level of consciousness.
Causes
  -	   Motor Vehicle Accidents (MVA)
  -	   Pedestrian Vehicle Accident (PVA)
  -	   Assault injuries
  -	   Fall from heights
  -	   Sports injuries
  -	   Missile injuries e.g. gunshot wounds
                                                                             Neurosurgery
Investigations
  -	   RBG, FBC, PT, PTT, Blood Grouping and Cross Matching
  -	   Urea and Electrolytes
  -	   Toxicology screening e.g. alcohol, illicit drugs screening
  -	   Arterial Blood Gas Levels are very important
  -	   Skull x- ray to look for fracture
  -	   Brain CT scan
Management
  -	 The Primary goal of therapy is to prevent secondary brain
     injury which is done by maintaining adequate perfusion and
     ventilation.
  -	 After following ATLS guidelines for management of trauma
     patients, management follows the severity of the head trauma.
  -	 Mild head trauma
        	 Bed rest with head off bed (HoB) elevated to 30-45 degrees
        	 Neuro checks every 2 hours or every hour if more
           concerned
        	 NPO until alert, then clear fluids and advance to other
           foods as tolerated
        	 Isotonic IV fluids mainstay being N/Saline running at
           usually 100mls/hr
        	 Mild analgesia: paracetamol PO or PR if NPO
                                                                           Neurosurgery
       	 Seizure within the first 24 hours of injury
       	 GCS less than or equal to 10
       	 Penetrating brain injury
       	 History of significant alcohol intake
       	 Cortical (hemorrhagic) contusion on CT-Scan
Complications
  -	 Post-traumatic seizures
  -	 Permanent neurological disability
  -	 Post-traumatic hydrocephalus
  -	 Post-Concussion Syndrome
  -	 Infection e.g. Meningitis, brain abscess, chronic osteitis etc.
  -	 Chronic traumatic encephalopathy
  -	 Subdural hematoma
  -	 It is a collection of blood between the Dura Mater and arachnoid
     layer. It is subdivided into acute (< 72hours) Subacute (between
     72 hours and 3 weeks) and Chronic ( > 3weeks).
  -	 The most commonly seen are acute and chronic subdural
     hematoma
Causes
  -	   Fall
  -	   Motor vehicle accident
  -	   Assault
  -	   Child abuse (Shaken Baby Syndrome)
Investigations
  -	 Fundoscopy in case of Shaken Baby Syndrome (retinal
     hemorrhage can be evidenced)
  -	 CT scan (to visualize crescentic hematoma and midline shift)
Management
  -	 General management of head injury
  -	 Indications for surgery
       	 Subdural hematoma thickness greater than 10mm
       	 Midline shift greater than 5mm as seen on CT scan
       	 Less of the above but with decreasing of GCS between the
           time of injury and hospital by 2 or more points or fixed and
           dilated pupils and or ICP exceeds 20mmHg
Cause
  -	 Minor head injury or fall often not remembered by patients or
     relatives.
Risk factors
  -	   Old age
  -	   Alcohol abuse
  -	   Seizures
  -	   Cerebral spinal fluid shunts
  -	   Anticoagulation
                                                                            Neurosurgery
  -	   Decreased consciousness
  -	   Sphincter disorder
  -	   Bilateral papilloedema on fundscopy
Investigations
  -	 Coagulation screening
  -	 ECG
  -	 CT scan which shows hypo or isodense fluid collection in
     crescentic shape and midline shift
  -	 MRI
Management
  -	 Stabilization of patients according to ACLS protocol
  -	 Surgery by a trained surgeon
Definition: It is the collection of blood between the skull and the Dura
Mater caused by a rupture of artery and vein in epidural space, as a
result of a fracture of the skull at the moment of the impact in 60-90%
of cases.
Causes
  -	   Motor Vehicle Accidents (MVA)
  -	   Pedestrian Vehicle Accident (PVA)
  -	   Assault injuries
  -	   Fall from heights
  -	   Sports injuries
Investigations
  -	 X-ray can show the fracture of the skull
  -	 CT scan can show biconvex shaped hematoma adjacent to the
     skull
Management
  -	 Initial management according to ATLS
  -	 Epidural hematoma in posterior fossa and temporal region are
     especially dangerous
  -	 Surgical treatment is commonly indicated to remove hematoma
     as soon as possible
Complications
  -	 Permanent neurological deficit
  -	 Prolonged coma leading to pressure sores, DVT, pulmonary and
     urinary infection
Causes
  -	   Motor Vehicle Accidents (MVA)
  -	   Pedestrian Vehicle Accident (PVA)
  -	   Assault injuries
  -	   Fall from heights
  -	   Sports injuries
  -	   Missile injuries
Investigations
  -	 X-ray shows bone lesion or intracranial foreign bodies in case of
     penetrating injury
  -	 CT scan is the investigation of choice
Management
  -	 Initial management is according to ATLS protocol
  -	 Surgery is indicated in:
        	 Progressive neurological deterioration referable to the
            TICH, medically refractory intracranial hypertension or
            signs of mass effect on CT Scan
        	 TICH > 50ml                                                      2
        	 GCS = 6-8 with frontal or temporal TICH volume > 20ml
                                                                           Neurosurgery
            with midline shift  to 5mm and/or compressed basal
            cisterns on CT
Complications
  -	   Post-traumatic seizures
  -	   Permanent neurological disability
  -	   Post-traumatic hydrocephalus
  -	   Prolonged coma leading to pressure sores, DVT, pulmonary and
       urinary infection
Causes
  -	 Pathological
  -	 Injury to the chest
                                                                            Surgery
                                                                            Cardio Thoracic
  -	   Difficulty breathing
  -	   Chest wall wound (bruise, contusion or laceration)
  -	   Shallow and rapid breathing
  -	   Localized tenderness on palpation
  -	   Altered percussion note
  -	   Reduced breath sound on auscultation
Investigations
  -	 CXR
  -	 CT scan and MRI
Management
  -	 Admit the patient
  -	 Analgesics for pain control
       	local infiltration using 2% lignocain)
       	SC morphine according to patient body weight
       	NSAID (ibuprofen or diclofenac either oral or per rectal)
- Chest physiotherapy
Complications
  -	 Atelectasis
  -	 Pneumonia
Cause
  -	 Trauma to the chest
Investigations
  -	 CXR
  -	 CT scan and MRI
Management
  -	   Admission
  -	   High flow oxygen by mask
  -	   Position patient on the injured side
  -	   Analgesia
  -	   Restricted fluid administration
  -	   Monitor oxygen saturation
  -	   Intubate if patient not responding
  -	   Admit to ICU for mechanical ventilation
Complications
  -	 Associated injuries (lung contusion, haemothorax,
     pneumothorax and pericardial tamponade)
  -	 Pneumonia
  -	 Empyema thorasis
3.1.3. Pneumothorax
Causes
  -	 Chest trauma
  -	 Spontaneous
  Tension pneumothorax
        	 Chest pain
        	 Bruising, contusion, laceration of chest wall
        	 Severe dyspnea                                                           3
        	 Cyanosis
                                                                                Surgery
                                                                                Cardio Thoracic
        	 Mental confusion
        	 Sweating
        	 Reduced chest movement
        	 Displacement of the tracheal and apex beat
        	 Absent breath sounds on affected side
        	 Hyperresonance
        	 Hypotension
        	 Jugular venous distension
  Simple pneumothorax
       	 Chest pain
       	 Shallow respiration
       	 Bruising, contusion, laceration of chest wall
       	 Reduced breath sounds
       	 Heperresonance
Investigations
  -	 Clinical diagnosis for tension pneumothorax
  -	 CXR, CT scan for simple pneumothorax
Management
  Tension pneumothorax
        	 Wide bore cannula in the second intercostals space mid-
           clavicular line
        	 High flow oxygen by mask
        	 Analgesia for pain
        	 Monitor oxygen saturation
        	 Chest tube insertion with underwater seal connection
  Simple pneumothorax
       	 High flow oxygen by mask
       	 Analgesia
       	 Monitor oxygen saturation
       	 Chest tube insertion under water seal connection
Complications
  -	 Collapse lung
  -	 Lung contusion
  -	 Pneumonia
3.1.4. Haemothorax
Cause
  -	 Chest trauma
Investigations
  -	 CXR
  -	 CT scan
Management
  -	   High flow oxygen by mask
  -	   Analgesia
  -	   Chest tube insertion under water seal connection
  -	   May transfuse
  -	   Thoracotomy may have to be done if initial drainage is more than
       1.5 L of blood or if active drainage is more than 200 ml/ hour
Cause
  -	 Chest trauma
                                                                                  Surgery
                                                                                  Cardio Thoracic
  -	   On ECG there is electrical alternans
  -	   Pulsus paradoxicus
  -	   FAST (focused abdominal sonography in trauma); pericardial
       effusion
Investigations
  -	 CXR
  -	 CT scan
  -	 ECG
Management
  -	 High flow oxygen
  -	 Analgesia
  -	 Pericardiocentesis (sub xyphoid approach)
Investigations
  -	 CXR
  -	 CT scan
Management
  -	 High flow oxygen
  -	 Analgesia
  -	 Restricted fluid administration
  -	 Monitor oxygen saturation
  -	 Intubation and mechanical ventilation if not responding to the
     above
  -	 May require chest drainage if associated pneumothorax and
     haemothorax.
Cause
  -	 Trauma
Investigations
  -	 CXR
  -	 CT scan
Management
  -	 High flow oxygen
  -	 Analgesia
  -	 Surgical intervention after stabilization
                                                                                 Surgery
                                                                                 Cardio Thoracic
Signs and symptoms
Investigations
  -	   Sputum exam
  -	   CXR
  -	   CT scan
  -	   Bronchoscopy
Management
Causes
  -	 Inhalation of food particles
  -	 Virulant pyogenic bacterials like S.Aureus and Klebsiella in a
     background of immune compromise
Investigations
  -	   Sputum examinations
  -	   CXR
  -	   CT scan
  -	   Bronchoscopy
Management
  -	 Apropriate antibiotics (e.g. Clindamycin for 3 to 6 weeks)
  -	 Chest physiotherapy
  -	 Surgery(lobectomy)
                                                                                 Surgery
                                                                                 Cardio Thoracic
Causes
  -	 Post pulmonary TB infection
  -	 Pneumoconiosis
  -	 Fungal infections ( e.g. aspergilosis)
Investigations
  -	   CXR
  -	   Sputum examination
  -	   CT scan
  -	   Bronchoscopy
Management
  -	   Treat underlying condition (TB, aspergilosis)
  -	   Chest physiotherapy
  -	   Symptomatic treatment
  -	   Lobectomy or pneumonectomy
Causes
  -	 Unknown
  -	 Predisposing factors include:
       	 Smoking
       	 Exposure to dusts from industrial pollution
  -	 Central tumors
       	 Cough
       	 Chest pain
       	 Hemoptysis
       	 Wheezing
       	 Dyspnea
       	 Finger clubbing
       	 Loss of weight (not very common)
       	 Dull percussion note
       	 Crepitations on auscultation
       	 Reduced breath sound
       	 Metastases to other organs
       	 Paraneoplastic syndromes
  -	 Peripheral tumors
       	 Cough
       	 Chest pain
       	 Pleural effusion
       	 Dyspnea
       	 Finger clubbing
       	 Crepitations on ausculatation
       	 Reduced air entrance
       	 Metastases to other organs
       	 Paraneoplastic syndromes
Investigations
  -	 CXR
  -	 Chest and brain CT scan
  -	 Bronchoscopy and biopsy
  -	 Mediastinoscopy
  -	 Pleural effusion aspiration for cytology
  -	 Pleural biopsy
Management
  -	 Radiotherapy
  -	 Chemotherapy
  -	 Surgery
                                                                                Surgery
                                                                                Cardio Thoracic
       	 Severe coughing
       	 Severe dyspnea
       	 Cynosis
       	 Wheezing
       	 Absent or reduced breath sound
  -	 Penetrating objects
       	 History penetrating trauma
       	 Cough
       	 Chest pain
       	 Maybe assymptomatic
       	 Reduced air entrance
       	 Crepitations
       	 Dull percussion note
Investigations
  -	 CXR
  -	 CT scan
  -	 Bronchoscopy
Management
  -	 Inhaled foreign body is an emergency (refer to ENT section)
  -	 For penetrating foreign body
       	 If symptomatic do thoracothomy and removal
       	 If assymptomatic, reassure patient and follow up
Causes
  -	 Posterior compartment
       	 Neurogenic tumors
       	 Enteric cysts
       	 Lymphomas
       	 Lymphadenopathies
       	 Bronchogenic tumors
       	 Oesophagial tumors
Investigations
  -	   CXR
  -	   CT scan
  -	   MRI
  -	   Bronchoscopy
  -	   Mediastinoscopy
Management
  -	 Management will depend on the type of lesion and mediastinal
     compartment affected.
Note:
 For more information refer to relevant textbooks (Short Practice of
 Surgeryby Bailey and Love and Principles of Surgery by Schwartz)
                                                                                Surgery
                                                                                Cardio Thoracic
  -	 There are two types
       	 Postero- lateral hernia (Bochdalek Hernia)
       	 Anterior Hernia (Morgagns Hernia)
Cause
  -	 Unknown
  -	 Bochdalek Hernia
       	 They manifest at birth
       	 Severe dyspnea
       	 Cyanosis
       	 Failure to feed
       	 In drawing of the chest
       	 Bowel sounds heard in the chest
       	 Reduced or absent air entrance
       	 Displacement of the apex beats to the right
  -	 Morgagnis Hernia
       	 It may be assymptomatic
       	 Symptoms of intestinal obstraction
       	 Dyspnea
       	 Recurrent tachycardia
Investigations
  -	   CXR
  -	   Gastrografin swallow
  -	   Abdominal x-ray
  -	   CT scan
Management
  -	 High flow oxygen by mask
  -	 Intubation and ventilation
  -	 Surgery
Causes
  -	 Blunt: road traffic accidents, falls, sports injuries
  -	 Penetrating: stab injuries, bullet and blast injuries
Clinical features
  -	 Initial abdominal exams are often normal and may be initially
     assymptomatic
  -	 Pain and tenderness increase and spread from the injury site to
     the other parts of the abdomen, frequently the entire abdomen
  -	 The abdomen becomes tender, distended, and rigid
  -	 Bowel sounds disappear
  -	 The patient becomes progressively sicker, develops fever, and
     usually vomits
  -	 Patient may fall into shock
  -	 Respirations are shallow and rapid because it hurts to breathe            4
     deeply
                                                                             Injuries
                                                                             Abdominal
  -	 Abdominal pain is increased by moving, straightening the knees,
     or taking a deep breath
  -	 The patient frequently prefers to lie quietly on his back or side
     with the knees flexed
   Blunt Trauma
                               Hemodynamically Stable?
                          no                                  yes
             Distending Abdomen?                         Viscous
                   No                               Injury Suspected?
                     DPL or US
                                       _            CT/US/DPL
  yes             +
                                                     +        _
                                   Other
   Laparotomy                      Tests       Laparotomy               Observe
 Laparoscopy                                            +
                                          Explore            DPL           CT
                                                                    +
                                        _      _
             _                                                                  _
                                                            Laparotomy
                          Observe
OPERATIVE PROCEDURE
 Grade I and II
      	 Manual compression
      	 Suture ligature
      	 Omental patch
      	 Closed suction drain
      	 Argon beam coagulation
      	 Topic haemostatics
  Grade III to IV
       	 Definitive treatment or damage control
       	 Resectional debridment
       	 Perihepatic packing
       	 Baloon tamponade
       	 Foley catheter tamponade
Causes
Investigations
Complications
  -	 Pancreatic pseudocyst
  -	 Duodenal or pancreatic fistula (treat with somatostatin/surgery)
Management
DUODENUM
 -	 Often in unrestrained drivers, handlebar injuries
 -	 Suspect with history, blood in NGT aspirate, or retroperitoneal
    air
 -	 Difficult to diagnose without CT scan
OPERATIVE FINDINGS
 -	 Upper retroperitoneal hematoma
 -	 Bile leakage
OPERATIVE PROCEDURE
 -	 Cattels maneuver
 -	 Pyoric exclusion, gastrostomy, jejunostomy
DIAPHRAGM
  -	 Left hemidiaphragm more commonly injured
  -	 Elevation on chest x-ray, but may be normal
  -	 Difficult to visualize injuries by other means (including CT, MRI)
  -	 Injuries may be missed for years
                                                                                   4
Management
                                                                                 Injuries
                                                                                 Abdominal
  -	 Early: laparatomy, reduce abdominal contents from chest and
     repair
  -	 Late: present as diaphragmatic hernia. Reduce and repair defect
     in diaphragm
Management
  -	   Immediate surgery
  -	   Resection of devitalized bowel with primary anastomosis
  -	   Stop mesenteric haemorrhage
  -	   Peritoneal lavage
  -	 Immediate surgery
  -	 Primary closure and proximal defunctioning colostomy/
     ileostomy
  -	 Peritoneal lavage
  -	 Excision and exteriorization of two ends with re-anastomosis at
     3months
Diagnosis
Management
  -	 Primary repair
  -	 +/- colostomy
  -	 +/- pre-sacral drainage
Cause
- Congenital
Diagnosis
- Clinical
Investigations
Complications
  -	   Aspiration pneumonia
  -	   Chocking and possible death
  -	   Feeding problems
  -	   Reflux after surgery
  -	   Stricture of the oesophagus
Management
5.1.2. Achalasia
Causes
  -	 Regurgitation of food
  -	 Chest pain increasing after eating may also be felt in the back,
     neck and arms
  -	 Cough
  -	 Heart burn
  -	 Unintentional weight loss
  -	 Signs of anaemia or malnutrition
Investigations
  -	 Oesophagium manometry
  -	 Esophagogastroduodenoscopy
  -	 Upper Gastro-intestinal x-ray with barium meal
Complications
  -	 Regurgitation
  -	 Aspiration pneumonia
  -	 Perforation of esophagus
Management
Investigations
Complications
  -	 Bleeding
  -	 Reflux oesophagitis and necrosis
  -	 Ballets oesophagus
  -	 Benign strictures
  -	 Oesophagioadenocarcinoma
  -	 Chronic cough
  -	 Laryngitis
  -	 Pharyngitis
Management
  General
       	 Lose weight and avoid smoking, coffee and chocolates
       	 Avoid tight garments and stooping
       	 Avoid sleeping before 2 hours post prandial
  Medication
       	 Control acid secretion with proton receptor antagonists
          (e.g. ranitidine), proton pump inhibitors (e.g. omeprasol),
          Dose:
       	 Minimize effects of reflux (give alginic acids e.g. gaviscon),
          Dose:
       	 Antacids (e.g. magnesium hydroxide), Dose:
       	 Prokinetic agents (e.g. metoclopramide), Dose:
  Surgical treatment
        	 Nissen fundoplication is the standard surgical treatment
        	 Vagotomy as an obsolete treatment
Causes
Symptoms
  -	   Regurgitation
  -	   Chest pain unrelated to eating
  -	   Difficulty swallowing solids or liquids
  -	   Heartburn
  -	   Vomiting blood
  -	   Weight loss
Investigations
  -	   Barium swallow
  -	   Chest MRI or thoracic CT to determine stage of the disease
  -	   Endoscopic ultrasound to determine stage of the disease
  -	   Esophagogastroduodenoscopy and biopsy
  -	   PET (positron emission tomography) scan
  -	   Stool testing may show blood
Management
Complications
  -	 Difficulty swallowing
  -	 Severe weight loss from not eating enough
  -	 Metastasis of tumour to other areas
Causes
  -	 Not known
  -	 Predisposing factors include: very cold or hot beverages
  -	   Dysphagia
  -	   Regurgitation
  -	   Substernal midline chest pain
  -	   Odynophagia
Diagnosis
  -	 Clinical
  -	Investigations:
        	 Barium swallow (typical corkscrew oesophagus) x-rays
        	 Oesophageal radionuclide transit test (oscillatory or non
           clearance pattern)
Management
  Medical
       	 Botulium toxins
       	 Long acting nitrites
       	 Benzodiazepines
       	 Psychotropic drugs
       	 Pneumatic dilatation
       	 Calcium channel blockers
  Surgery
       	 Considered if medical treatment has failed
       	 Long oesophageal myotomy
Causes
  -	   Pain
  -	   Difficulty swallowing
  -	   Chest pain
  -	   Difficulty bleeding
  -	   Tachycardia
  -	   Fever
  -	   Tachypnoea
  -	   Nasal voice (cervical injury)
  -	   Haematamesis (thoracoabdominal segment injury)
  -	   Supraclavicular swelling and crepitus (subcutenias emphizema)
  -	   Neck pain or stiffness (on perforation of oesophagus)
  -	   Respiratory distress (thoracic injuries)
Investigations
  -	 Chest x-ray may reveal air in the soft tissues of the chest, fluids
     leaked from oesophagus to the space surrounding lungs or lung
     collapse
  -	 A chest CT scan may show an abscess in the chest or oesophageal
     cancer
  -	 Endoscopy (incomplete intramural perforations/ Mallory-Weiss
     Syndrome)
Complications
Management
 Medical
      	 Administering fluids
      	 IV antibiotics to prevent or treat infections
      	 Draining fluids collected around the lung with a chest tube
      	 Mediasternoscopy to remove fluids collected in the
         mediasternum                                                                  5
                                                                                  System
                                                                                  Gastro-Intestinal
                                                                                  Disorders of
Definition: It is the protrusion of the upper part of the stomach into the
thorax through a tear or weakness in the diaphragm.
  -	   May be assymptomatic
  -	   Dull pains in the chest
  -	   Shortness of breath
  -	   Heart palpitations
Diagnosis
  -	Clinical
  -	Investigations
       	 Upper GI series,
       	 Endoscopy
       	 High resolution manometry
Management
  General
       	 Treatment may not be required
       	 Bed elevation after meals
       	 Stress reduction techniques
       	 Weight loss if overweight
  Medical
       	 Proton pump inhibitors
       	 H2 receptor blockers
  Surgical
        	 Nissens fundoplication
Complications
  -	   Oesophageal cancer
  -	   Gasbloat Syndrome
  -	   Dysphagia
  -	   Dumping Syndrome
  -	   Achalasia
Causes
  Inflammatory
        	 Secondary bacterial peritonitis: localized, generalized
        	 Primary bacterial peritonitis: generalized
        	 Tertiary peritonitis: generalized, very poor prognosis
  Traumatic
       	 Injury to solid organs: acute intra abdominal bleeding
       	 Peritonitis secondary to intestinal injury
  Obstructive
       	 Acute intestinal obstruction (small bowel)                                   5
       	 Chronic intestinal obstruction (colonic)
                                                                                  System
                                                                                  Gastro-Intestinal
                                                                                  Disorders of
  Vascular
       	 Mesenteric infarction
       	 Strangulated external/internal hernia
       	 Volvulus (small or large intestine)
  -	   Pain
  -	   Appetite: anorexia, nausea, vomiting, dysphasia, weight loss
  -	   Bowels habits: bloating, diarrhea, constipation, flatulence
  -	   Tenderness
  -	   Rigidity
  -	   Masses
  -	   Altered bowel sounds
  -	   Evidence of malnutrition
  -	   Bleeding
  -	   Jaundice
Diagnosis
  -	 Clinical presentation
  -	 Investigations
        	 Haemogramme
        	 Renal function tests and electrolytes
        	 Amylase
        	 Chest x-ray and abdominal films (erect/supine)
        	 Blood culture for high fever and pyrexia
        	 Ultrasound and CT-scan
        	 DPL
        	 Mesenteric angiography
        	 Laparoscopy/laparotomy
Management
5.3. Peritonitis
Causes
  -	 Bacterial peritonitis
       	 Secondary bacterial peritonitis (from GIT): common
       	 Primary bacterial peritonitis (streptococcal): rare
       	 Tertiary bacterial peritonitis (ICU patients): uncommon
  -	 Chemicals
      	 HCL (early Perforated PUD)
      	 Extravasation of urine (bladder rupture)
      	 Bile (leak post cholecystectomy)
      	 Amylase (pancreatitis)
  -	 Dehydration
  -	 Local symptoms: pain (localized or generalized) severe, constant,
     aggravated by movement
  -	 Local signs
  -	 Loss of normal abdominal movement on respiration
  -	 Tenderness, guarding, rigidity, rebound tenderness
  -	 Silent abdomen
  -	 Digital rectal examination may elicit pelvic tenderness, boggy
     swelling, and cervical tenderness in females
Management
Complications
  -	 Septic shock
  -	 Hypovolemic shock
  -	 Multiple organ failure
Causes
  -	 Extramural
  -	 Adhesions, bands
  -	 Hernias: internal and external
  -	 Compression by Tumors
  -	Intramural
  -	 Inflammatory disease: Crohns disease
  -	 Tumors: carcinomas, lymphomas, etc.
  -	 Strictures
  -	 Intraluminal
  -	 Feacal impaction
  -	 Swallowed foreign bodies
  -	 Bezoars
  -	 Gallstone
  -	   Rectal examination
  -	   May reveal an obstructing mass in the pouch of Douglas
  -	   Feel apex of an intussusceptions
  -	   Faecal impaction or an empty rectum (in case of sigmoid
       volvulus)
The rule that constipation is present in intestinal obstruction does not
apply to Richters Hernia, vascular occlusion and intestinal obstruction
associated with pelvic abscess.
Investigations
Management
-	 Operative treatment
     	 Proper timing of the operation for intestinal obstruction is
        essential. Surgery is the most important step, and in case of
        strangulation or vascular occlusion it is the only effective
        treatment. Surgical procedures for the relief of intestinal
        obstruction may be divided into five categories.
-	 Surgical procedures
      	 Relief of intestinal obstruction may be divided into five
         categories
           	 Procedures not requiring opening the bowel-
               lysis of adhesions, manipulation-reduction of
               intussusceptions, reduction of obstructed hernia.
           	 Enterotomy - for removal of obturation obstruction-
               gallstones, bezoars.
           	 Resection of obstructing lesion or strangulated bowel
               with primary anastomosis.
           	 By-pass: anastomosis around an obstruction.
           	 Formation of a cutaneous stoma proximal to the
               obstruction- catheter enterostomy, caecostomy.
Summary of treatment
   	 IV fluid replacement
   	 Bowel decompression via nasogastric tube
   	 Broad spectrum antibiotics preoperatively for mechanical
      obstructions                                                                 5
   	 Adynamic ileus patients: conservative management - IV
                                                                              System
                                                                              Gastro-Intestinal
                                                                              Disorders of
5.4.1. Appendicitis
Causes/Predisposing factors
Investigations
Management
  Medical treatment
       	 Augmentin 1gm x 3/ day/ 5 days if uncomplicated
           appendicitis
  Alternative
        	 Ceftriaxone/2g 24 hourly for 5-7 days (adults), or
           Cefotaxime 1g/ every 8 hours + Metronidazole 500mg/every
           8 hours IV
  Surgical treatment
        	 Open or laparoscopic appendicectomy and
           antibioprophylaxis ceftriaxone 2 gm single dose +
           metronidazole 500mg single
Causes/Aetiology
  -	 Idiopathic
  -	 An obstruction (food waste or fecal stone)
  -	 An infection
                                                                                      5
Signs and symptoms
                                                                                 System
                                                                                 Gastro-Intestinal
                                                                                 Disorders of
  -	 Aching pain that begins around your navel and often shifts to
     your lower right abdomen
  -	 Pain that becomes sharper over several hours
  -	 Tenderness that occurs when you apply pressure to your lower
     right abdomen
  -	 Sharp pain in your lower right abdomen that occurs when the
     area is pressed on and then the pressure is quickly released
     (rebound tenderness)
  -	 Pain that worsens if you cough, walk or make other jarring
     movements
  -	 Nausea
  -	 Vomiting
  -	   Loss of appetite
  -	   Low-grade fever
  -	   Constipation
  -	   Inability to pass gas
  -	   Abdominal swelling
Diagnosis
  -	Clinical
  -	Investigation
       	 CT scan of the abdomen and the appendix
  -	 Peritonitis
  -	 Surgical wound infections
  -	 Intra-abdominal abscess
  -	 Fistulas
  -	 Small bowel obstruction (adhesions)
  -	 Paralytic ileus
  -	 Infertility
  -	 Sepsis
Management
Interval Appendicectomy
                                                         Resolved       Persistent
                                                                        Mass or pain
Laparotomy
Definition: Gall stones are solid particles that form from bile in the
gallbladder. They are of two types namely (1) cholesterol stones (20%)
and (2) pigment stones yellow stones (80%).
Causes/Risk factors
Investigations
Complications
Management
  -	 Symptomatic treatment
  -	 Intake of only clear liquids to give the gallbladder a rest
  -	 Avoid fatty or greasy meals
  -	 Take acetaminophen (Tylenol, etc.) for pain
  -	 Laparascopic cholecystectomy should be performed for patients
     with symptoms
Cause
Symptoms
Investigations
Management
  Medical
       	 IV fluids
       	 Ampicilline IV 1 g tid for 7days + Gentamycin IV 160 mg
          OD for 5days
  Alternative
        	 Ceftriaxone IV 1gm bid for 7days
        	 Pethidine 100mg IV 3-4 times/ per day for analgesia
  Surgical
        	 Cholecystectomy is a definitive treatment, if performed
           with in 2-3 days of illness it is better than delayed
           chelecystectomy that is performed 6-10 weeks after initial
           medical treatment
        	 Laparoscopic cholecystectomy is the procedure of choice
5.4.5. Jaundice
Causes
  -	   Choledocholithiasis
  -	   Periampullary carcinomas
  -	   Portal lymphadenopathy
  -	   Sclerosing cholangitis
  -	   Frank Jaundice
  -	   Pruritis
  -	   White stool
  -	   Coca-cola coloured urine
Investigations
  -	 Serum bilirubine
  -	 Liver function test
  -	 Alkaline phosphatase: elevated
  -	 -GT: elevated
  -	 Transaminase: normal/elevated
  -	 Lactate dehydrogenase: normal/elevated
  -	 Reticulocytes: normal
  -	Ultrasound
  -	CT-scan
  -	PTC
  -	ERCP
Management
  Surgical
         	 Surgical obstructive jaundice will always be accompanied
            by dilatation of the biliary tree
              	 Establishing the cause of the jaundice
              	 Assessment of the general condition of the patient
              	 Staging in patients with tumours
              	 Surgical (endoscopic, radiological)
Causes
  - 	 Benign
         	 Peptic ulcer disease
         	 Infection, such as tuberculosis and infiltration diseases
            such as amyloidosis.
         	 A rare cause of gastric outlet obstruction is obstruction
            with gallstone, also termed Bouverets Syndrome.
  -	Malignant
       	 Tumours of stomach, including adenocarcinoma( and
          its linitis plastic variant, lymphoma, and gastrointestinal
          stromal tumour
       	 Occasionally, cancers near the pylorus, for example, of
          pancreas or duodenum.
Investigations
  -	 Esophagogastroduodenoscopy(EGD)
  -	 Abdominal x-ray (Gastric Fluid level)
  -	 Abdominal CT scan
Management
  Pharmacological
      	 In patients with peptic ulcer disease, the oedema will settle
         with conservative management with nasogastric suction,
         replacement of fluids and electrolytes and proton pump
         inhibitors
  Surgical
        	 Antrectomy (which involves anastomosing the duodenum
           to the distal stomach) or gastrojejunostomy, indicated in
           cases of failed medical treatment and recurrent obstruction
Causes/predisposing factors
Investigations
Management
  Surgery
       	 Resection of the tumour with adequate margins to include             6
          regional lymphnodes
                                                                           Colon and Rectum
                                                                           Disorders of the
Definition: The passage of blood from the anus, the blood volume may
be small or large, and may be bright red or dark in colour.
Causes
Management
6.3. Haemorrhoids
Causes
Investigations
  -	 Flexible sigmoidoscopy
  -	Colonoscopy
Complications
Management
Anal fissure:
  -	 First line treatment: stool softeners / balking agents, local
     anaesthetic gels 0.2% GTN ( Glyceryl trinitrate) ointment
  -	 Second line treatment:
        	 Botulinum toxin injection, lateral internal sphincterotomy
        	 Examination under anaesthesia and biopsy for atypical/
             suspicious abnormal fissures
Causes/Risk factors
Investigations
  -	 Proctosigmoidoscopy
  -	 Ultrasound/CT scan/MRI to rule out other diseases
Complications
  -	   Anal fistula
  -	   Body-wide infection (sepsis)
  -	   Continuing pain
  -	   Problem keeps coming back (recurrence)
  -	   Scars
Management
                                                                                    6
                                                                                Colon and Rectum
                                                                                Disorders of the
Causes
  -	 Perianal discharge
  -	 Pain
  -	 Swelling
  -	 Bleeding
  -	 Skin excoriation
  -	 External opening
  -	 Digital rectal examination may reveal a fibrous tract or cord
     beneath the skin
  -	 Lateral or posterior indurations suggests deep post anal or
     ischiorectal extension
  -	 Recurrent episodes of anorectal sepsis
  -	 An abscess develops easily if the external opening on the perianal
     skin seals itself
Investigation
- Rectoscopy
Complications
  -	 Incontinence
  -	 Recurrent pain after surgery
Management
Staging process
Causes/Risk factors
Investigations
Management
  -	 Surgery
        	 Local resection
        	 Abdominoperineal resection
  -	 Combined local radiotherapy and chemotherapy: This displaced
     the traditional abdominoperineal resection
Causes
Investigations
Management
Complications
  -	 Pancreatic abscess
  -	 Intra-abdominal sepsis
  -	 Necrosis of the transverse column
  -	 Respiratory failure (ARDS) or renal failure (Acute tubular
     necrosis)
  -	 Pancreatic hemorrhage
  -	 Pancreatic pseudo cyst: may need to be drained internally or
     externally
  -	 Chronic pancreatitis
                                                                                    6
                                                                                Colon and Rectum
                                                                                Disorders of the
Causes
Management
  Medical
       	 Analgesia
        	 Exocrine pancreatic enzyme replacement
  Surgical
         	 Drainage of dilated pancreatic duct or excision of the
            pancreas in some cases
        	 Splanchanicectomy is performed in intractable pain
                                                                           Disorders
                                                                           Genito-Urinary
             7. Genito-Urinary Disorders
Causes
  -	   Hematuria(>99%)
  -	   Flank tenderness / ecchymosis
  -	   Hemodynamic instability
  -	   Flank pain
  -	   Signs and symptoms of other abdominal injuries are present
Investigations
  -	   FBC
  -	   Renal function tests
  -	   Ultrasonography
  -	   Prothrombine time
  -	   Thromboplastine time
  -	   IVP (visualization or non-vis)
  -	   CT scan with contrast
Management
  -	 Grade IV to V
        	 Requires surgical exploration, nephrectomy done after
           confirming a functioning contralateral kidney
Causes
  -	 Usually iatrogenic
  -	 Penetrating trauma more common than blunt trauma
  -	 Unilateral
  -	 Assymptomatic, secure ligation of the ureter gives silent atrophy
     of the kidney
  -	 Tenderness in the loin
  -	 Fever, possible with pyonephrosis due to infection of the
     obstructed system
  -	 Urinary fistula through the wound
  -	 Abdominal distension following uroperitoneum
  -	 Bilateral
  -	 Ligation of both ureters gives anuria
  -	 No passage of ureteric catheter
  -	 Bilateral hydronephrosis
Investigations
Management
                                                                                      7
  -	 Delayed diagnosis (less than 5 days) consider repair
                                                                                  Disorders
                                                                                  Genito-Urinary
  -	 If greater than 5 days, control urinary extarvasation with ureteral
     stent, urinary diversion and urinoma drainage
Causes
  -	   No bladder distension
  -	   Gross hematuria
  -	   Difficult or inability to void
  -	   Suprapubic or abdominal pain or tenderness
  -	   Abdominal distension
  -	   Delayed presentation associated with intoxication due to uric
       acid accumulation
Investigations
  -	   FBC
  -	   Renal function test
  -	   Ultrasonography
  -	   CT scan
  -	   Retrograde cystography
  -	   Intravenous urography
Management
Causes
Investigation
- Retrograde urethrogram
Management
Complications
  -	 Impotence
  -	 Incontinence
  -	 Strictures
Cause
                                                                                   Disorders
                                                                                   Genito-Urinary
Signs and symptoms
  -	   Scrotal pain
  -	   Ecchymosis
  -	   Hematocele
  -	   Swelling of testis
Investigations
  -	 FBC
  -	 Ultrasonography
Management
Cause/Risk factors
  -	   Upper UTI
  -	   Fever
  -	   Chills/rigors
  -	   Flank pain
  -	   Malaise
  -	   Anorexia
  -	   Costovertebral angle and abdominal tenderness
  -	   Lower UTI
  -	   Dysuria
  -	   Frequency
  -	   Urgency
  -	   Suprapubic pain
  -	   Hematuria
  -	   Scrotal pain (epididymo-orchitis) or perineal pain (prostatitis)
Investigations
Complications
                                                                                Disorders
                                                                                Genito-Urinary
Management
7.2.2. Hematuria
Diagnosis
  -	 Physical exam
       	 Abdominal exam - abdominal masses (including renal or
          bladder) or tenderness
       	 GU exam - DRE for prostate, external genitalia in males
Investigations
Management
Causes
                                                                                  Disorders
                                                                                  Genito-Urinary
Signs and symptoms
Investigations
Complications
Management
Causes/risk factors
  -	   Uretheral stricture
  -	   Perirectal abcesses
  -	   Poor perineal hygiene
  -	   Diabetes
  -	   HIV
  -	   Immunocompromised states
  -	   Fever
  -	   Perineal and scrotal pain
  -	   Cellulitis
  -	   Necrosis of the scrotum
  -	   Flanking skin
  -	   Crepitus
Investigations
  -	   FBC
  -	   HIV test
  -	   Glycemia
  -	   Pus culture for sensitivity
Management
Causes/risk factors
  -	 Cryptorchidism
  -	 Risk is unaffected by orchidopexy
  -	 Higher incidence in the whites
                                                                                  Disorders
                                                                                  Genito-Urinary
Investigations
Management
7.3.4. Hydrocele
Causes
  -	 Congenital
  -	 Idiopathic
  -	 Secondary (intrascrotal pathology such us tumour, torsion,
     trauma or infection)
  -	   Fluctuant
  -	   Trans-illuminate
  -	   Swelling
  -	   Non tender
Investigations
  -	 Ultrasound
  -	 Urinalysis
  -	 FBC
Management
  -	 Surgery
  -	 Lords procedure in adults
  -	 Herniotomy in children
Causes/risk factors
- Prematurity
Investigations
Management
                                                                                  Disorders
                                                                                  Genito-Urinary
7.3.6. Varicocele
Investigation
Management
7.4.1. Priapism
Causes/risk factors
  -	 Persistent erection
  -	 Tenderness of the penis
  -	 Cavernous bodies rigid while the glans will be flaccid
Investigations
Management
                                                                                     7
        	 Distal shunt (winter shunt)
                                                                                 Disorders
                                                                                 Genito-Urinary
        	 Proximal shunt if distal shunt fails
7.4.2. Paraphymosis
Causes
  -	 Trauma
  -	 Latrogenic
Management
7.4.3. Phymosis
Causes
  -	 Congenital
  -	 Secondary to infection
Management
- Circumcision
7.4.4. Hypospadias
Investigations
Complications
Management
  Surgical management
         	 During the surgery, the penis is straightened and the
            hypospadias is corrected using tissue grafts from the
            foreskin. The repair may require multiple surgeries
                                                                                  Disorders
                                                                                  Genito-Urinary
         	 Relief of the chordee
         	 Urethral reconstruction
         	 In some cases, more surgery is needed to correct fistulas or
            a return of the abnormal penis curve
Recommendations
  -	 Oriental origin
  -	Age
  -	 Human papillovirus (HPV) and balanitis xerotica obliteran
     infection
  -	Smoking
  -	 Smegma and phymosis
  -	 Treatment of psoriasis with UV light
  -	AIDS
  -	 Poor hygiene related to non circumcision and STDs
  -	   Redness
  -	    Irritation
  -	   Sore on the penis
  -	   Indurations or erythema
  -	   Ulceration
  -	   Small nodule, or an exophytic growth
Diagnosis
Management
 Primary lesion
      	 Circumcision: lesion localized to the prepuce
      	 Radiotherapy: glans alone affected and tumor  1cm
7.4.6. Impotence
Causes
  -	 Psychological
  -	 Neurological causes (spinal cord lesions, myelodisplasia,
     multiple sclerosis, tabes dorsalis,peripheral neuropathies)
  -	 Diabetes mellitus
  -	 Endocrine (hypogonadotrophic hypogonadism Klinefelters
     Syndrome or surgical orchidectomy)
  -	 Low testosterone levels (prolactin producing tumors)
  -	 Vascular(atherosclerosis)
  -	 Trauma (perineal, posterior urethra, pelvic fracture leading to
     arterial injury, uraemicchronic dialysis
  -	 Iatrogenic (radical prostatectomy, cystoprostatectomy,
     neurological surgical procedures,transurethral endoscopic
     procedures, pelvic irradiation procedures)
  -	 Medication (centrally acting agents, anticholinergic
     agents (antidepressant), anti-androgenic agents (digoxin),
     hyperprolactinemic agent (cimetidine), sympatholitic agent
     (methyl dopa)
Diagnosis
  -	   Detailed history
  -	   Physical examination
  -	   Length, plaques and deformity of the corporal bodies of penis
  -	   Presence or absence of testis
  -	   Size and consistency of the penis
                                                                                      7
  -	
                                                                                  Disorders
                                                                                  Genito-Urinary
       Gynecomastia (endrogene deficiency)
  -	   Neurological assessment
  -	   Sensory function of the penis and perineal skin
  -	   Bulbo cavernosus reflexe to evaluate the sacral reflexes
Investigations
Management
 Psychological
       	 Treated by trained psychotherapist or sex therapist
 Medical therapy
      	 Sildenafil(viagra), tadalafil (cialis)
      	 Apomorphine (uprima)
      	 Intracorporal administration of vasoactive substances
          (papaverine hydrochloride alone or associated with
          vasodilator like phentolamine, or prostaglandin E1)
      	 Androgen replacement therapy with testosterone
      	 Vacuum suction devices
 Surgical therapy
       	 Penile prostheses
       	 Vascular surgical techniques like micro surgical
          anastomosis of inferior epigastric artery to the dorsal
          penile artery
Causes
  -	 Congenital
  -	 Failure of normal canalization
  -	 Treat at time of endoscopy with dilatation, internal urethrotomy
  -	 Trauma
  -	 Instrumentation (most common, at fossa navicularis)
  -	 External trauma
  -	 Urethral trauma with stricture formation
  -	 Infection
  -	 Common with gonorrhea in the past (not common now)
  -	 Long-term indwelling catheter
  -	 Balanitis xerotica obliterans - causes meatal stenosis
Investigations
Management
  -	   Uurethral dilatation
  -	   Temporarily increases lumen size by breaking up scar tissue
  -	   Healing will reform scar tissue and recreate stricture
  -	   Not usually curative
                                                                                 Disorders
                                                                                 Genito-Urinary
  -	 Internal urethrotomy (IU)
  -	 Endoscopically incise stricture without skin incision
        	 Only single and short (< 1 cm), bulbar urethra strictures
           respond
        	 Cure rate 50-80% with single treatment, < 50% with
           repeated courses
Causes
  -	 Not known
  -	 Predisposing factors are age, normally functioning testes, race,
     geographical location, sexual behavior, diet, alcohol, tobacco (no
     evidence that they play a part).
  -	   Nocturia
  -	   Urgency and frequency
  -	   Weak stream and hesitancy
  -	   Acute urinary retention
  -	   Urinary tract infections
  -	   Renal failure
  -	   Urinary stones
  -	   Haematuria
Management
Causes/Risk factors
  -	 Age
  -	 Family history
Investigations
Management
                                                                                   Disorders
                                                                                   Genito-Urinary
7.7. Disorders of the Urinary Bladder
Causes
Investigations
Complications
Management
  -	   Painless
  -	   Gross haematuria is the commonest presentation
  -	   Microscopic heamaturia
  -	   Irritative voiding symptoms
                                                                                Disorders
                                                                                Genito-Urinary
Causes/Risk factors
  -	 Cigarette smoking
  -	 Age
  -	 Cyclophosphamide
  -	 Phenacetin
  -	 Chemical exposure at work  carcinogens (dye workers, rubber
     workers, aluminum workers, leather workers, truck drivers, and
     pesticide applicators)
  -	 Chemotherapy
  -	 Radiation treatment
  -	 Bladder infection
Diagnosis
  -	 Clinical
  -	Investigations
  -	 Urine cytology
  -	 Cystoscopy
  -	 Upper tract/abdominal/pelvic evaluation with CT scan or
     intravenous pyelography (IVP)
  -	 TURBT for tissue diagnosis (Histopathological analysis)
Note:
 If tests confirm bladder cancer, staging is done to see if the cancer
 has spread. Staging helps guide future treatment and follow-up
 and gives idea on patient prognosis.
Management
Most patients with stage IV tumors cannot be cured and surgery is not
appropriate. In these patients, chemotherapy is often considered.
Treatment Summary
7.7.3. Cystocele
Causes
                                                                                Disorders
                                                                                Genito-Urinary
Signs and symptoms
  -	 Urine leakage
  -	 Incomplete emptying of the bladder
  -	 Bladder emptying impaired
  -	Frequency
  -	Nocturia
  -	 Stress incontinence
  -	 Relaxation of the anterior vaginal wall and descent of the urethra
     and bladder when the patient strains to void
Investigations
  -	 Urinalysis
  -	 Ultrasonography
Management
Classification
                                                                                  Disorders
                                                                                  Genito-Urinary
Diagnosis
  -	   Detailed history
  -	   Poor flow, hesitancy
  -	   Post micturation dribble (outflow obstruction)
  -	   Dysuria (infection)
  -	   Hematuria (possibility of tumour)
  -	   Sexual function (males), bowel function (both sex) point toward
       neurological cause
  -	   Mobility and mental status (incontinence in elderly)
  -	   Past or present illness (diabetes, surgery e.g. abdominal perineal
       resection, hysterectomy DRE for the prostate in male
  -	   DVE for female for cystoureterocele
  -	   Neurological assessment
Investigations
  -	RFT
  -	 Urine microscopy and culture
  -	IVU
  -	Urodynamics
  -	Cystometry
  -	Cystoscopy
  -	Cystogram
Management
  -	 If urge incontinency
         	 Treat the underlying cause
         	 Pharmaceutical therapy: anticholinegic and/or smooth
            muscle relaxant (oxybutynin, emepronium carageenate,
            flavoxate hydrochloride) associated with bladder exercise
  -	 Surgical therapy
       	 Cystoscopy and bladder distention
       	 Partial bladder denervation by subtrigonal phenol injection
           or pre sacral neurectomy
       	 Augmentation cystoplasty (bladder enlargement) or
           substitution cystoplasty(bladder substitution)
       	 Urinary diversion (ileal conduit)
  -	 If stress minor incontinence
         	 Pelvic flow exercise
         	 Estrogen therapy
         	 Sympathomimetics (ephedrine or alpha adrenergic agonist
            e.g. phenylpropanolamine)
  -	 If nocturnal enuresis
         	 Bladder training during the day gradually increasing
            interval between voiding
         	 Voiding last thing at night
         	 Lift the child before bed
         	 Enuresis alarm
         	 Drugs: imipramne (tofranil), propantheline,oxybutynin,
            desmopressin
         	 Augmentation cystoplasty (if failure of medical treatment)
  -	   Evaluate
  -	   Any child with febrile urinary infection
  -	   Any boy with urinary infection
  -	   Any girl with recurrent UTI
Investigations
  -	 Ultrasonography
  -	 Voiding cystourethrogram
  -	 Hereditary, be suspicious in siblings and screen with imaging
     studies
                                                                                  Disorders
                                                                                  Genito-Urinary
Management
7.8.2. Calculus
Causes
  -	   Renal infections
  -	   Inadequate urinary drainage and urinary stasis
  -	   Prolonged immobilization
  -	   Decreased urinary citrate
  -	   Dietetic (deficiency of vitamin A)
  -	   Altered urinary solutes and colloids
  -	   Hyperparathyroidism
Investigations
  -	 Kidney/Ureter x-ray
  -	 Bladder x-ray
  -	 Abdominal ultrasound
Management
Complications
  -	 RCC can extend into renal vein, up the IVC (inferior vena cava)
     and into the atrium.
Management
  Palliation
        	 Renal artery embolisation (may stop hematuria)
        	 Chemotherapy (10% response rate)
        	 Hormonal therapy (5% response rate)
        	 Immunotherapy (under review)
  Surgery
       	 Partial nephrectomy, if small peripheral lesions
       	 Radical nephrectomy (Gerotas fascia and regional
          lymphnodes)
       	 Isolated lung metastases should also be removed surgically
                                                                                 Disorders
                                                                                 Genito-Urinary
  -	 Fever/ convulsions
  -	Cough
  -	Anorexia
  -	 Nausea and vomiting
  -	 Hematuria (in about 20% of cases)
  -	 High Blood Pressure in 25  60%
  -	 Coagulopathy can occur in 10%
Investigations
  -	FBC
  -	 Renal function test
  -	 Liver function test
  -	 An Ultrasound
  -	 CT scan or MRI
  -	 Chest x-ray
  -	 Plain abdominal x-ray
  -	IVP
  -	 Surgical biopsy
Management
  -	 If unilateral tumours
         	 chemotherapy: Adriamycin, vincristine or doxorubicine for
            52 weeks followed by
         	 nephrectomy
  -	 If bilateral tumours
         	 Partial nephrectomy and chemotherapy
         	 Radiotherapy
Cause
Investigations
  -	 Ultrasound
  -	 Diuretic renal scan
Management
They are relatively rare. They account for approximately 10% of all
renal tumours and approximately 5% of all urotherial tumours.
Causes/risk factors
  -	 Tobacco smoking
  -	 Drinking coffee (observed for people who take > 7cups of coffee/
     day)
  -	 Analgesic abuse
  -	 Chronic infections, irritations
  -	Hereditary
Investigations
  -	 Urine cytology
  -	IVU
  -	Ultrasonography
  -	 Retrograde ureterography
  -	 Antigrade pylography
  -	 CT scan
  -	 Chest x-ray
  -	Cystoscopy
  -	Ureteroscopy
                                                                                  Disorders
                                                                                  Genito-Urinary
Management
Causes
  -	Obstructive
  -	 Benign prostatic hyperplasia
  -	 Cancer of prostate
  -	 Uretheral stricture
  -	 Bladder neck obstruction
  -	 Trauma of the pelvis
  -	Phymosis
  -	 Pelvic masses and gynecology malignancies
  -	 Infectious and inflammatory
  -	 Acute prostatitis
  -	Vulvovaginitis
  -	Neurologic
  -	 Spinal and peripheral nerve injuries
  -	 Spinal compression
  -	 Cerebrovascular disease
  -	 Guillain Barre Syndrome
  -	 Diabetes mellitus
  -	Tumours
  -	Pharmacologic
  -	 Anticholinergics and alphadrainergic agents
Investigations
  -	Ultrasonography
  -	 CT scan brain, spine, pelvis if suspicion of neurologic lesion
  -	 Plain x-ray
Management
Complication
Causes
Investigations
                                                                                 Disorders
                                                                                 Genito-Urinary
Management
- Congenital
Investigations
  -	Urinalysis
  -	 Ultrasound scan
  -	 Voiding cyctogram (dilatation of the urethra above the valves)
Management
Cause
Investigations
  -	Urinalysis
  -	RFT
  -	FBC
  -	Ultrasonography
  -	Urethrogram
  -	IVU
Management
  -	 Treatment infections
  -	Dilatation
  -	 Optical urethrotomy
Causes
  -	 Idiopathic
  -	 Predisposing factors: age, normally functioning testes, sexual
     behavior, diet, alcohol, tobacco (no evidence that they play a
     part)
                                                                                  Disorders
                                                                                  Genito-Urinary
Signs and symptoms
  -	Nocturia
  -	 Urinary urgency and frequency
  -	 Acute urinary retention
  -	 Urinary tract infections
  -	 Renal failure
  -	 Urinary stones
  -	 Haematuria
Management
  Conservative management
  Medical therapy
       	 Alpha Blockers: e.g.
       	 Androgen suppression: e.g.
  Surgery
       	 Trans urethral microwave thermotherapy
       	 Transurethral needle ablation
       	 Trans-urethral Resection prostate (TURP)
       	 Open surgery: Prostatectomy
7.10.2. Adenocarcinoma
Causes/Risk factors
Investigations
Management
Causes/Risk factors
  -	 Cigarette smoking
  -	 Chemical exposure at work (carcinogens - dye workers, rubber
     workers, aluminum workers, leather workers, truck drivers, and
     pesticide applicators)
  -	 Chemotherapy (e.g. cyclophosphamide)
  -	 Radiation treatment
  -	 Chronic bladder infection or irritation (e.g. schistosomiasis)
Investigations
  -	Urinalysis
  -	Cystoscopy
  -	 Intravenous pyelography ( IVP)
  -	 TURBT for tissue diagnosis (Histopathhnological analysis)
                                                                                Disorders
                                                                                Genito-Urinary
  -	 Intravenous pyelogram - IVP
  -	 CT scan of the upper urinary tract Pelvic CT scan
Complications
  -	Anemia
  -	 Hydronephrosis
  -	 Urinary incontinence
Management
Note:
  Most patients with stage IV tumours cannot be cured and surgery
  is not appropriate. In these patients, chemotherapy is often
  considered
Treatment summary
Causes/Risk factors
Investigations
                                                                               Disorders
                                                                               Genito-Urinary
Management
Note:
  RCC can extend into renal vein, up the IVC and into the atrium
                                                                          Burns
Causes
Assessment of burns
Note:
   Nasotracheal or endotracheal intubation is indicated especially if
   patient has a severe increase in hoarseness, difficulty swallowing
   secretions, or increased respiratory rate with history of inhalation
   injury.
  -	 Secondary survey
       	 Coincident trauma diagnosed and treated
       	 Burns are further characterized by estimating extent of
          burn depth
  -	Firstdegree
       	 Superficial (sunburn)
       	 Erythema, pain, absence of blisters
       	 Consists of epidermal damage alone
  -	Second-degree
      	 Entire epidermal layer
      	 Part of underlying dermis
      	 Mottled and red, painful, swelling and blisters
  -	Fourth-degree
      	 Full-thickness
      	 Extending into muscle, tendons or bones
      	 Typically involves appendage
      	 Black and dry
      	 NOT painful
Management
                                                                         Burns
    and hypertonic solution for infected wounds
 -	 debridement of devitalized tissue and debris
 -	 Apply topical antibacterial agent:
      	 Bacitracin ointment on face / ears
      	 Silver sulfadiazine on the body
      	 Ensure aseptic procedures
Causes
Investigations
Complications
                                                                             Burns
Management
Note:
  These drugs provide diuresis for the toxic myoglobin, which can
  help prevent acute tubal necrosis and renal failure secondary to
  myoglobinuria.
9.2. Rabies
Causes
Rabies is spread by infected saliva that enters the body through animal
bite or broken skin
  -	   Paresthesia
  -	   Headache
  -	   Stiff neck
  -	   Lethargy
  -	   Pulmonary symptoms
  -	   Maniacal behaviour
  -	   Muscle spasm of throat with dysphasia
  -	   Convulsion coma paralysis death
Investigations
Complications
Management
  -	 Local care
       	 Thorough irrigation
       	 Cleansing with soap solution
  -	 Most of the time, stitches should not be used for animal bite
     wounds
  -	 Immunization and treatment for possible rabies are
     recommended for at least up to 14 days after exposure or a bite
Causes
  -	 Eyes (spitting cobras and ringhals can eject their venom quite
     accurately into the eyes of the victims, resulting in direct eye pain
     and damage)
  -	 Swelling and tissue damage
  -	 Suddenly develop breathing difficulty and go into shock
  -	 Local effects (swollen, bleeding, blister and gangrene)
  -	 Nervous system effects (vision problems, speaking and breathing
     trouble, and numbness close to or distant to the bite site, and
     death without treatment)
  -	 Muscle death (muscle necrosis, rhabdomyolysis, kidney failure)
Diagnosis
  -	 Hypotension
  -	Weakness
  -	Nausea/vomiting
  -	 Pain, swelling, tenderness and ecchymosis at site of bite
  -	 Paresthesia and muscle fasciculations
  -	 Defect in blood coagulation
  -	 Pulmonary edema
                        Grading of envenomation
 Grade                       Signs and Symptoms
 0  No envenomation         Fang marks, minimal pain, small edema and
                             erythema
Recommendations
                    Painful progressive
                                                     Progressive
Dominant clinical   swelling (PPS)
                                                     Weakness (PW)
Presentation of     Bleeding may occur                                              Combined PPS
                                                     PPS occurs in no-spitting                             Bleeding (B)
victim              in puff adder bites                                             And PW
                                                     cobra bites
                    (thrombocytopenia)
                    and Gaboon adder bites
                                                                                                                                   9
Hospitalisation        Take the patient to         Take the patient to            Take the patient to     Take the patient
                       hospital                    hospital                       hospital                to hospital
Antivenom may be
                          Puff adder, spitting                                                              Boomslang
necessary for threat                                    All species                     Rinkhals
                          cobras, Gaboon
to limb or life           adder
See Algorithm 3
Percentage bites in
which antivenom is            < 10%                   50  70%                         < 10%                80 -100%
indicated
  -	 Localized pain	
  -	 Petechial hemorrhages
  -	 Swelling of skin and mucus membrane
  -	 Generalized erythema
  -	 Abdominal cramps		
  -	 Pulmonary and cerebral edema
  -	 Blurred vision	
  -	 Vascular collapse
  -	 Death results from combination of shock
  -	 Respiratory failure and CNS changes
  -	 Most death from insect stings occur within 15 to 30 minutes
  -	 Early application of a tourniquet may prevent rapid spread of
     venom
  -	 Emergency kit containing epinephrine commercially available
Note:
  Most patients recover within 24 hours
10. References
                                                                             References
8.	 Blaylock RSM. Normal oral bacterial flora from some Southern
    African snakes. Ondestepoort Journal of Veterninary Research 2001;
    68: 175 82
9.	 S. Terry Canale (1998): Campbells Operative Orthopaedics, 9th
    Edition
10.	 Chaaralambour CP, Siddique et al. Early versus Delayed Surgical
     Treatment of open Tibial Fractures; effects on the rate of infection
     and need of secondary surgical procedures to promote bone
     union. Injury 2005; 36:656-661.
11.	 Chitra S. Mani and Dennis L. Murray. Rabies. Pediatr. Rev., Apr
     2006; 27: 129 - 136.
12.	 Coetzer PWW, Tilbury CR. The epidemiology of snakebite in
     Northern Natal. S Afr Med J 1982; 62: 206  12.
13.	 Current orthopaedics 4th Edition (2006) Harry B. Skinner,
     MD, PhD is Professor and Chairman of the Department of
     Orthopaedic Surgery at the University of California, Irvine
14.	 Edwards IR, Fleming JBM, James MFM. Management of a Gaboon
     viper bite : a case report. Cent Afr J Med 1979; 25: 217  21
15.	 Evans EI, Purnell OJ, Robinett PW, et al: Fluid and electrolyte
     requirements in severe burns. Ann Surg 1952; 135:804815
16.	 Fractures of the Pelvis and Acetabulum 2nd Edition Marvin
     TileBaltimore, Williams and Wilkins, 1995.
17.	 Gross T et al.: Multiple-trauma management: standardized
     evaluation of the subjective experience of involved team members.
     European Journal of Anaesthesiology (2005), 22: 754-761
18.	 Henley MB, Chapman JR, Agel J et al.Treatment of Type 1, 11A,
     111B open fractures of Tibial Shaft a Prospective comparison of
     interlocking intramedullary nails and half-pin external fixators.
     Journal of Orthopedic Trauma 1998; 12:1-7.
19.	 Herndon DN (Ed): Total Burn Care. Philadelphia, Elsevier
     Saunders, 2007
20.	 Jane Curtis. Insect Sting Anaphylaxis. Pediatr. Rev., Aug 2000; 21: 256.
21.	 KanuOkike, BA and Timothy Bhattacharyya MD, Trends in
     Management of Open Fractures, A Critical Analysis. The American
     Journal of Bone and Joint Surgery 2006; 88:2739  2748.
22.	 Kauvar D, Lefering R &Wade C (2006) Impact of Hemorrhage
     on Trauma Outcome: An Overview of Epidemiology, Clinical
     Presentations and Therapeutic Considerations, 60 (6): S3-S11
23.	 Malasit P, Warrell DA, Chanthavanich P, Viravan C,
     Mongkolsapaya J, Singhthong B, Supich C. Prediction, prevention,
     and mechanism of early (anaphylactic) antivenom reactions in
     victims of snake bites. Br Med J 1986 292: 17  20
24.	 McNally SL, Reitz CJ. Victims of snakebite: A 5-year study at
     Shongwe Hospital, Kangwane, 1978  1982. S Afr Med J 1987; 72:
     855  60
25.	 Moppett IK: Traumatic brain injury: assessment, resuscitation and
     early management. BJA (2007) 99 (1): 18-31.
26.	 Muller GJ. Black and brown widow spider bites in South Africa. S
     Afr Med J 1993; 83: 399 -405
27.	 Muller GJ. Scorpionism in South Africa. S Afr Med J 1993; 83: 405
      11Bergman NJ. Scorpion sting in Zimbabwe. S Afr Med J 1997;
     87: 163  7
28.	 Patzakis MJ, Bains et al. Prospective, randomized, double blind
     study comparing single agent antibiotic therapy ciprofloxacin to
     combination antibiotic therapy in management of open fracture
     wounds. Journal of Orthopedic Trauma 2000;14:529-533.
41.	 Rupprecht CE, Briggs D, Brown CM, et al. Centers for Disease
     Control and Prevention (CDC). Use of a reduced (4-dose) vaccine
     schedule for postexposure prophylaxis to prevent human rabies:
     recommendations of the advisory committee on immunization
     practices. MMWR Recomm Rep. 2010 Mar 19;59(RR-2):1-9.
     Erratum in: MMWR Recomm Rep. 2010 Apr 30; 59(16):493.
     [PubMed]
42.	 Bassin SL, Rupprecht CE, Bleck TP. Rhabdoviruses. In: Mandell
     GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious
     Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone;
     2009: chap 163.
43.	 Handbook of Neurosurgery, Seventh Edition by Mark S.
     Greenberg (2010)
44.	 Principles of Neurosurgery, Second Edition by Setti S. Rengachary
     (2004)