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Of Penicillin. Addition of Sulbactam Increases Resistance To Beta Lactamases, Enzymes Produced by Bacteria That May Inactivate Ampicillin

This drug order is for Ampicillin + Sulbactam, an anti-infective combination of aminopenicillin and beta lactamase inhibitor given intravenously at 4.5 grams for 8 hours to treat an infected wound by binding to bacterial cell walls and inhibiting enzymes that can inactivate ampicillin, broadening its antibiotic spectrum.

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47 views1 page

Of Penicillin. Addition of Sulbactam Increases Resistance To Beta Lactamases, Enzymes Produced by Bacteria That May Inactivate Ampicillin

This drug order is for Ampicillin + Sulbactam, an anti-infective combination of aminopenicillin and beta lactamase inhibitor given intravenously at 4.5 grams for 8 hours to treat an infected wound by binding to bacterial cell walls and inhibiting enzymes that can inactivate ampicillin, broadening its antibiotic spectrum.

Uploaded by

KathzkaMaeAgcaoili
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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1.

Generic Name: Ampicillin + Sulbactam

Date and Time the Drug Ordered: August 4, 2015 @ 5:30 P.M

Classification: Anti- infectives, aminopenicillins, Beta lactamase inhibitors

Dosage/route/frequency: 4.5 grams IV for 8 hours ANST (-)

Mechanism of Action: Binds to bacterial cell wall, resulting in cell death, spectrum is broader than that
of penicillin. Addition of sulbactam increases resistance to beta lactamases, enzymes produced by bacteria
that may inactivate ampicillin.

Desired Effect: This drug was given to our patient to treat his infected wound.

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