MCQs on SCHIZOPHRENIA

ASSESSMENT Of 30 mcqs

FPSC No : 51
MCQs on SCHIZOPHRENIA
Submission deadline : 9 APRIL 2013 12 NOON

INSTRUCTIONS
• To submit answers to the following multiple choice questions, you are required to log on to the
College On-line Portal (www.cfps2online.org).
• Attempt ALL the following multiple choice questions.
• There is only ONE correct answer for each question.
• The answers should be submitted to the College of Family Physicians Singapore via the College
On-line Portal before the submission deadline stated above.

1. The first psychotic episode of schizophrenia is often 5. With regards to the longitudinal course of
preceded by a prodromal phase lasting weeks or schizophrenia, what is proportion of patients will
even years. Which of the following symptoms is have a good outcome?
NOT consistent with the prodromal phase? (A) Less than 10%.
(A) Delusions. (B) Less than 20%
(B) Sleep disturbance. (C) Less than 30%
(C) Poor concentration. (D) Less than 40%.
(D) Irritability. (E) Less than 50%.
(E) Anxiety.
6. The Global Assessment of Functioning (GAF) score
2. About the symptoms that may be present in a is used to assess the level of functioning. What is the
patient with schizophrenia, which of the following GAF score that defines recovery in schizophrenia?
symptoms is LEAST LIKELY to be present? (A) 45 or more.
(A) Hallucinations. (B) 50 or more.
(C) 55 or more.
(B) Delusions.
(D) 60 or more.
(C) Alogia.
(E) 65 or more.
(D) Grandiosity.
(E) Anhedonia.
7. In the Singapore EPIP, patients rated their
satisfaction with the service provided by EPIP on
3. About the age of onset of schizophrenia in men,
the Client Satisfaction Questionnaire 8 (CSQ-8).
which of the following is CORRECT?
At the end of 2 years what was the proportion of
(A) 10 – 20 years.
patients who rated the level of satisfaction as “good
(B) 15 – 25 years.
or better”
(C) 20 – 30 years.
(A) 78.9%
(D) 25 – 35 years.
(B) 84.9%
(E) 30 – 40 years.
(C) 88.9%
(D) 94.9%
4. The genetic vulnerability in schizophrenia arises (E) 98.9%
from a complex combination of multiple genes of
small effect. Which of the following lifetime risk of 8. The concept of early intervention for psychosis
schizophrenia is CORRECT? resulted in several intervention sites being set up
(A) 25% for a child with patients who do not have the disorder. across the world. Which of the following matching of
(B) 13% for a child with one parent with schizophrenia. programme and site is CORRECT?
(C) 30% for a child with both parents with schizophrenia. (A) Early Assessment Service for Young People with Early
(D) 60% for a child with a monozygotic twin with schizophrenia. Psychosis Programme – Norway.
(E) The genetic vulnerability is too small to be of predictive value. (B) TIPS – Hong Kong.

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MCQs on SCHIZOPHRENIA

(C) Lambeth Early Onset (LEO) Service – London. 15. A proportion of patients with schizophrenia have
(D) The Prevention and Early Psychosis Program for Psychosis co-morbid psychiatric or medical conditions. What
(PEPP) – Calgary. is the prevalence?
(E) Early Psychosis Program – Ontario. (A) More than 30%
(B) More than 40%
9. The five most disabling conditions suffered by (C) More than 50%
mankind are matched with their ranked order. Which (D) More than 60%
of the matching is CORRECT? (E) More than 70%
(A) First – Dementia
(B) Second – Quadriplegia
16. What does the acronym GPPP stand for in the
(C) Third – Psychosis.
context of the collaboration between family doctors
(D) Fourth – Paraplegia
and the Institute of Mental Health in Singapore?
(E) Fifth – Blindness.
(A) General Practitioner-Patient Project.
(B) Generalist-Psychiatrist-Patient Partnership.
10. Between April 2007 and March 2011, EPIP screened
1293 individuals and accepted 815 into the (C) GP Partnership Programme.
programme. What is the biggest referral source of (D) General Practitioners’ Psychosis Project.
such individuals? (E) Generalist-Patient Psychosis Programme.
(A) Counsellor from welfare organization or school.
(B) Police or Court. 17. The GPPP is a collaboration for the care and
(C) General Practice or Polyclinic. management of patients with mental illness in the
(D) Hospital. community. What is the type of patients managed in
(E) Relatives, friends or self. this collaboration?
(A) Socially isolated patients.
11. Schizophrenia is a complex, heterogeneous, and (B) High risk patients.
disabling psychiatric disorder. What is its worldwide (C) Unemployed patients.
prevalence rate? (D) Financially needy patients.
(A) 1% (E) Stable patients.
(B) 2%
(C) 4%
18. About the patients suitable to be referred to family
(D) 6%
doctors in the GPPP, which of the following inclusion
(E) 8%
criteria is CORRECT?
(A) Patients not hospitalized within the last 6 months.
12. Bipolar disorder with psychotic features is a
differential diagnosis of schizophrenia. Which of the (B) Patients requiring the same maintenance medications for the
following supports a diagnosis of Bipolar disorder? last 6 weeks.
(A) Rapid onset and family history of affective disorder. (C) Patients who are unemployed.
(B) Hallucinations. (D) Patients who cannot afford expensive consultation fees.
(C) Paranoia. (E) Patients staying alone.
(D) Disorganised speech.
(E) Low energy. 19. About the patients suitable to be referred to family
doctors in the GPPP, which of the following IS NOT
13. Mental changes can occur with prescribed an exclusion criteria?
medications. Which of the medications and the (A) Olanzapine prescription.
mental changes is CORRECTLY paired? (B) Disruptive personality disorder.
(A) Corticosteroids and depression. (C) Substance use.
(B) Antidepressants and insomnia. (D) Formal psychotherapy.
(C) Beta-blockers and mania.
(E) Benzodiazepine-only prescription.
(D) Anticholinergics and somnolence.
(E) Levodopa and hallucinations.
20. About the satisfaction with the GPPP collaboration,
14. A schizoid personality disorder shares a common what is the level of patient satisfaction in the 2011
clinical feature with schizophrenia. What is it? survey?
(A) Anhedonia. (A) 58.1%
(B) Asociality. (B) 62,1%
(C) Alogia. (C) 78.6%
(D) Avolition. (D) 82.1%
(E) Delusional. (E) 98.6%

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21. One of the problems of schizophrenia is the high 26. Antipsychotics used in treatment of schizophrenia
rate of relapse of psychotic symptoms. What is the are heterogeneous compounds. They nevertheless
proportion of patients who may relapse within a share a common effect that is efficacious. What is
year of being hospitalized? that?
(A) Up to 20%. (A) They all block 5-HT2A neuroreceptors
(B) Up to 25%. (B) They all block D2 dopamine neuroreceptors.
(C) Up to 30%. (C) They all block M1 muscarinic neuroreceptors.
(D) Up to 35%. (D) They all block alpha1-adrenergic neuroreceptors.
(E) Up to 40%. (E) They all block H1 histamine neuroreceptors.

27. The typical antipsychotics or First generation

22. Treatment resistant schizophrenia is defined as
antipsychotics are divided by potency into high,
little or no symptomatic response to at least 2
intermediate and low. Which of the following has
antipsychotic trials of treatment at therapeutic dose
low potency?
range and adequate trial of treatment duration. (A) Thioridazine.
What is defined as adequate treatment duration? (B) Haloperidol.
(A) At least 4 weeks. (C) Perphenazine.
(B) At least 6 weeks. (D) Trifluoperazine.
(C) At least 8 weeks. (E) Fluphenazine.
(D) At least 10 weeks.
(E) At least 12 weeks. 28. In a patient with osteoporosis, an antipsychotic that
does not raise prolactin levels is desired. Which of
23. In a patient with proven treatment resistant the following antipsychotic will therefore be a good
schizophrenia, what is the drug of choice? choice?
(A) Aripiprazole. (A) Thiothixene.
(B) Haloperidol. (B) Aripiprazole.
(C) Olanzapine. (C) Respiridone.
(D) Respiridone. (D) Chlopromazine.
(E) Clozapine. (E) Thioridazine.

24. Early recognition of an impending relapse helps in 29. A patient with schizophrenia has a BMI of 29.
Which of the following antipsychotics will be a good
early treatment and avoidance of hospitalization.
choice?
Which of the following is an early symptom?
(A) Haloperidol.
(A) Hallucinations.
(B) Quetiapine.
(B) Delusions.
(C) Olanzapine.
(C) Difficulty concentrating.
(D) Zoprasidone.
(D) Asociality.
(E) Clozapine.
(E) Anhedonia.
30. Akathisia is an extrapyramidal symptom of
25. About relapse in schizophrenia, identification of antipsychotic therapy. Apart from dose reduction,
triggers is important. Which of the following is the which of the following medications helps to
LEAST LIKELY trigger? ameliorate this adverse effect?
(A) Cocaine use. (A) Benzodiazepine.
(B) Alcohol use. (B) Vitamin D.
(C) Cannabis use. (C) Propranolol.
(D) Low expressed emotion of caregivers. (D) Baclofen.
(E) Alcohol usage. (E) Dandrolene.

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