Course Code Course Title
PHM 103 Pharmaceutical Chemistry-IIA (Biochemistry)
Semester I Credits (Th+Pr) 3+1 Contact Hrs (Th+Pr) 5
Prerequisites None Knowledge Area
Basic Biomedical Sciences
Course This program will enable students to have:
Objectives A thorough education in basic knowledge of biochemistry related to macro molecules
that are physiologically active in living cells.
At the practical level, this program will help students to have extensive knowledge of
basic laboratory techniques of biochemistry and biochemical analyses, and will make
them competent in the most-extensively used techniques in the cellular, molecular, and
biochemical laboratories.
Course Outline
Weeks Topic Instructor Teaching Practical
strategy
1 GENERAL INTRODUCTION Dr. Noor Kamil Qualitative
AND BASIC BIOCHEMICAL analysis:
Lect 1
PRINCIPLES: Carbohydrates
General Introduction
GENERAL INTRODUCTION Dr. Noor Kamil
AND BASIC BIOCHEMICAL
PRINCIPLES:
Role of Pharmaceutical
Biochemistry in the health
Lect 2
profession. Nature of biochemical
reactions.
2 BASIC CHEMISTRY OF Department of Introduction to
BIOMOLECULES: Biochemistry spectrophotometrty
Lect 3
Carbohydrates: Introduction
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Lect 4
Carbohydrates: Chemistry,
Classification
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Lect 5
Carbohydrates: Reactions of
Carbohydrates
3 BASIC CHEMISTRY OF Department of Qualitative
Lect
BIOMOLECULES: Biochemistry analysis:
6
Carbohydrates: Optical activity Amino acids
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Carbohydrates: Biological and
Lect 7
pharmaceutical importance of
carbohydrates
BASIC CHEMISTRY OF Department of
Lect 8
BIOMOLECULES: Biochemistry
Lipids: Introduction
4 BASIC CHEMISTRY OF Department of Qualitative
BIOMOLECULES: Biochemistry analysis:
Lect 9
Lipids: Chemistry of Fatty acids Peptides and Sugar
and Lipids
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Lipids: Classification
Lect 10
(Saponifiable and non-
saponifiable lipids, Simple,
Complex and Derived lipids),
BASIC CHEMISTRY OF Department of
Lect 11
BIOMOLECULES: Biochemistry
Lipids: Reactions of Fatty acids
and other Lipids,
5 BASIC CHEMISTRY OF Nadia Ashraf Qualitative
BIOMOLECULES: Lipids: analysis:
Lect 12
Essential fatty acids, Biological Peptides and Sugar
and pharmaceutical importance of
lipids.
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Proteins Biochemistry
Lect13
and Amino acids: Chemistry,
Classification of proteins and
amino acids,
BASIC CHEMISTRY OF Department of
Lect 14
BIOMOLECULES: Proteins Biochemistry
and Amino acids: Reactions of
proteins and amino acids
6 BASIC CHEMISTRY OF Department of Qualitative
Lect 15
BIOMOLECULES: Proteins Biochemistry analysis:
and Amino acids: Organizational Proteins
levels
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Proteins Biochemistry
Lect 16
and Amino acids:
Macromolecular nature of
proteins,
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Proteins Biochemistry
and Amino acids: Biological and
Lect 17
pharmaceutical importance of
proteins and amino acids.
7 BASIC CHEMISTRY OF Department of Qualitative
Lect18
BIOMOLECULES: Biochemistry analysis:
Nucleic Acids: Proteins
Chemistry,
BASIC CHEMISTRY OF Department of
Lect 19
BIOMOLECULES: Biochemistry
Nucleic Acids: Types (DNA,
RNA, mRNA, tRNA, rRNA),
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Lect 20
Nucleic Acids: Purine and
Pyrimidine bases, Nucelosides,
Nucelotides
8 Mid term Lab Tutorial and
examination
Mid term
TUTORIAL
Lect21
EXAM PREP
9 BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Nucleic Acids: Structures of
Lect 22
nucleic acids, Biological and
pharmaceutical importance of
nucleic acids
BASIC CHEMISTRY OF Department of
Lect23
BIOMOLECULES: Biochemistry
Nucleic Acids: Tutorial for
Nucleic acids
BASIC CHEMISTRY OF
Lect24
BIOMOLECULES:
Vitamins:
Chemistry
10 BASIC CHEMISTRY OF Department of Qualitative
Lect
BIOMOLECULES: Biochemistry analysis:
25
Vitamins: Classification of Fat- Uric acid
soluble
BASIC CHEMISTRY OF Department of
Lect 26
BIOMOLECULES: Biochemistry
Vitamins: Classification of
water-soluble vitamins
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Vitamins: Biological and
Lect 27
pharmaceutical importance of
vitamins.
11 BASIC CHEMISTRY OF Department of Qualitative
Lect 28
BIOMOLECULES: Biochemistry analysis:
Vitamins: Tutorial examination Lipids and Sterols
(Cholesterol)
BASIC CHEMISTRY OF Department of
Lect 29
BIOMOLECULES: Biochemistry
Hormones: Chemistry,
Classification
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Lect 30
Hormones: Proteinous and
nonproteinous hormones, amino
acid derivatives, steroids
12 BASIC CHEMISTRY OF Department of Qualitative
Lect 31
BIOMOLECULES: Biochemistry analysis:
Biological and pharmaceutical Bile salts, Billirubin
importance of hormones
BASIC CHEMISTRY OF Department of
Lect 32
BIOMOLECULES: Biochemistry
Enzymes: Chemistry,
Classification, Mode of action
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Lect 33
Enzymes: Kinetics (Michaelis
Menten Equation and some
modifications)
13 BASIC CHEMISTRY OF Department of Qualitative
Lect 34
BIOMOLECULES: Biochemistry analysis:
Enzymes: Inhibition, Activation, Bile salts, Billirubin
Specificity, Allosteric enzymes,
BASIC CHEMISTRY OF Department of
Lect
BIOMOLECULES: Biochemistry
35
Enzymes: Factors affecting the
rate of an enzyme-catalyzed
reaction
BASIC CHEMISTRY OF Department of
Lect 36
BIOMOLECULES: Biochemistry
Enzymes: Biological and
pharmaceutical importance,
14 BASIC CHEMISTRY OF Department of Qualitative
BIOMOLECULES: Biochemistry analysis:
Lect 37
Enzymes: Mechanism of Analysis of
action of some important, Cholesterol and
Chymotrypsin Creatinine in Blood
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Lect 38
Enzymes: Mechanism of
action of some important,
Ribonuclease
BASIC CHEMISTRY OF Department of
BIOMOLECULES: Biochemistry
Lect
39
Enzymes: Tutorial for enzymes
15 BASIC CHEMISTRY OF Department of Qualitative
BIOMOLECULES: Biochemistry analysis:
Lect 40
Cell and Molecular Biology: Analysis of
Introduction to Cell Biology: Cholesterol and
The Chemical Basis of Life, Creatinine in Blood
BASIC CHEMISTRY OF Nadia Ashraf
BIOMOLECULES:
Lect41
Cell and Molecular Biology:
Techniques in Cell and
Molecular Biology.
Tutorial for Biochemistry and Nadia Ashraf
Lect 42
exam prep class
16 Exam prep class Department of
Lect 43
Biochemistry
Revision
Lect 44
Revision
Lect 45
Lab Outline
1. 2. Qualitative analysis:
a. Carbohydrates
b. Amino acids
c. Peptides and Sugar
d. Proteins
e. Uric acid
f. Lipids and Sterols (Cholesterol)
g. Bile salts, Billirubin
h. Analysis of Cholesterol and Creatinine in Blood
Reference Material
Lehninger AL. Principles of Biochemistry. 7th edition
Fundamentals of Biochemistry, 5th Edition; Voet, Voet and Pratt's
Berg JM, Tymoczko JL, Stryer L. Biochemistry. 7th Ed. WH Freeman and Company;
2010.
Bishop ML, Fody EP, Schoeff LE. Clinical Chemistry: Techniques, Principles
and Correlations. 6th Ed. Lippincott Williams & Wilkins; 2009.
Champe PC, Harvey RA. Illustrated Biochemistry. 4th Ed. Lippincot Company;
2007.
Chaterjee MN. Medical Biochemistry. 7th Ed. Jaypee Brothers Medical Publishers;
2007.
Conn EE, Stumpf PK. Outlines of Biochemistry. 5th Ed. John Willey & Sons; 1999.
Murray R, Rodwell V, Bender D, Kathleen M, Botham P, Weil A et al. Harper's
Illustrated Biochemistry. 28th Ed. Print-Hall; 2009.
West ES, Todd RW, Van BTJ. Text Book of Biochemistry. The MacMillan Co;
1996.