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Uterine Cancer

This document discusses endometrial cancer, also known as uterine cancer. It is the fourth most common cancer in women in the United States. Exposure to estrogen is a major risk factor. Symptoms include abnormal vaginal bleeding or discharge. Diagnosis involves pelvic exams, ultrasounds, biopsies, and other tests. Treatment may include hysterectomy, radiation therapy, chemotherapy, and hormone therapy. The 5-year survival rate is 75% for stage I and declines with more advanced stages.

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Ajurs Ursabia
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262 views20 pages

Uterine Cancer

This document discusses endometrial cancer, also known as uterine cancer. It is the fourth most common cancer in women in the United States. Exposure to estrogen is a major risk factor. Symptoms include abnormal vaginal bleeding or discharge. Diagnosis involves pelvic exams, ultrasounds, biopsies, and other tests. Treatment may include hysterectomy, radiation therapy, chemotherapy, and hormone therapy. The 5-year survival rate is 75% for stage I and declines with more advanced stages.

Uploaded by

Ajurs Ursabia
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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7/16/12

Uterine Cancer
Click to edit Master subtitle style

Endometrial cancer

7/16/12

Endometrial Cancer Uterine Cancer

fourth most common cancer in women frequently occurring gynecological cancer in the United State the US the life time risk of developing endometrial Ca is 2.4% in white women & 1.3% in black exposure to estrogen is considered the major risk factor

most In

Cumulative

September - Uterine Cancer Awareness Month

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Tamoxifen

an anti-estrogen used in the Rx of breast Ca has weak estrogenic activity on the genital tract 2 X risk of E Ca when used 5 Y

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Other Risk factors

risk in women with breast, ovarian

(endometrial type) & colorectal Ca


Diabetes

3X risk

Hypertension Previous Family

pelvic radiation therapy

Hx of endometrial Ca

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Pathophysiology
Uterine cancers are endometrioid

Three types
Type 1 majority of cases estrogen related occurs in younger, obese, and perimenopausal women. low grade and endometrioid

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Type
10% high

of cases grade and usually serous cell or clear

cell

older women and African American women Type


10%

affects

of cases hereditary and genetic types related to Lynch II syndrome

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Sympto ms
Abnormal

vaginal bleeding, spotting, or

discharge
Pain

or difficulty when emptying the

bladder
Pain Pain

during sex in the pelvic area

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Assessment and Diagnostic Findings


Pelvic

exam

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Ultrasound

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Biopsy

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Doctor may order one or more tests:


Pap

test

show cancer cells have spread to the cervix

Blood tests show how well the liver and kidneys

Chest x-ray show a tumor in the lung


CT

scan

can show cancer in the uterus, lymph nodes, lungs, or elsewhere.


MRI

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Staging
Stage

surface of the inner lining of the uterus. The doctor may call this carcinoma in situ.

0: The abnormal cells are found only on the

Stage

of the uterus to the endometrium. It may have invaded the myometrium.

I: The tumor has grown through the inner lining

Stage

II: The tumor has invaded the cervix. III: The tumor has grown through the uterus to

Stage

reach nearby tissues, such as the vagina or a lymph node.

Medical management
Surger y Hysterectomy

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Bilateral

salpingo-oophorectomy

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Radiation
therapy

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Chemothera py

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Hormone therapy

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Prognos is
The 5 Y survival rate for endometrial Ca :
Stage Stage Stage Stage

I 75% II 58% III 30% IV 10%

Overall

5 Y survival 70% most Pt present early due to abnormal vaginal bleeding

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Thank You
Click to edit Master subtitle By: style April Joy Ursabia

Maricel Barbas

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