COLORECTAL CANCER
COLORECTAL CANCER
COLORECTAL CANCER
COLORECTAL CANCER
                     DEFINITION
is a disease in which cells in    Colorectal cancer starts in
the colon or rectum grow out      the colon or the rectum.
of control. Sometimes it is       These cancers can also be
called colon cancer, for short.
                                  called colon cancer or rectal
The colon is the large
                                  cancer, depending on where
intestine or large bowel. The
                                  they start. Colon cancer and
rectum is the passageway
that connects the colon to the    rectal cancer are often
anus (Center for Disease          grouped together because
Control and Prevention,           they have many features in
2023).                            common.
Facts:
• Malignancy of colon/rectum
• If the disease is detected and
  treated at an early stage, the 5
  year survival rate is 90%.
• Only 34% of colorectal cancers
  are found at an early stage.
• Colon polyps and early cancer
  can have no symptoms.
  Therefore, regular screening is
  important.
PATHOPHYSIOLOGY
• Arise from preexisting benign
  adenomatous colon polyps
• Transformation is slow = 1 cm polyp
  take 7 years to progress to invasive
  carcinoma
• (Adenomastically round and polypoid)
• Lesions penetrate the colon wall and
  extend into surrounding tissue
• Lungs and liver metastasize
• Complications: perforation,
  abscess formation, peritonitis,
  sepsis, and shock.
RISK FACTORS
•   Age > 40, increasing age
•   Family history of colon CA or polyps
•   Previous colon CA
•   Personal hx of ulcerative colitis, Crohn’s disease for more than 10
    years
•   Onset is 63-67 years old
•   Whites than African Americans
•   Incidence higher in industrialized western world
•   High fat diet, high intake of protein(beef), low fiber diet
•   Excess alcohol intake
•   Genital CA or breast CA
CLINICAL MANIFESTATIONS
• Change in bowel habits, constipation, diarrhea, and bowel
  incontinence
• Hematochezia
• Melena
• Unexplained anemia
• Unusual stomach or gas pain
• Unexplained weight loss
• Fatigue
• Vomiting
SCREENING TEST FOR COLORECTAL CANCER
 High-sensitivity fecal occult blood test (FOBT)
     guaiac FOBT –detects heme
     immunochemical FOBT- uses antibodies to detect
      hemoglobin protein
 Colonoscopy
MEDICAL MANAGEMENT
 Surgery           Radiation therapy
                    • Should be done after
   • Polypectomy
                      surg. healing
   • Local
     excision
   • Resection
   • colostomy
NURSING MANAGEMENT
Pre-operative care
• Low residue or liquid diet
• Cathartics to accelerate defection
• Antibiotics
• Enema
• Identify anxiety and provide supportive efforts
NURSING MANAGEMENT
Post-operative care
• Assess return of peristalsis, motility, flatus and bowel sounds
• Absence of ABD pain, distension, bloating, nausea and vomiting
• Check for rectal bleeding
• Promote optimal nutrition
• Promote ventilation
Preventive measurements
• High fiber, low fat diet
• Avoid salt cured or nitrite cured foods
• Avoid obesity
• Annua; occult exam > 50 years old (F/M)
• Sigmoidoscopy every 5-10 years
• Total colon exam every 5-10 years
Nursing diagnosis
• CONSTIPATION RELATED TO OBSTRUCTIVE LESIONS
• ACUTE PAIN RELATED TO TISSUE COMPRESSION
  SECONDARY TO OBSTRUCTION
• FATIGUE RELATED TO ANEMIA AND ANOREXIA
• IMBALANCED NUTRITION, LESS THAN BODY
  REQUIREMENTS RELATED TO NAUSEA AND ANOREXIA
• RISK FOR FLUID VOLUME DEFICIT RELATED TO VOMITING
  AND DEHYDRATION
• ANXIETY RELATED TO IMPENDING SURGERY
• DISTURBED BODY IMAGE RELATED TO COLOSTOMY