RETROGRADE
URETHROGRAPHY
          Dr.
          B.Harikrishna
              PGRD
             NORMAL ANATOMY OF MALE URETHRA
   ~17.5 to 20 cms in length
       Anterior (Penile and Bulbous)
          Contains periurethral littre glands
       Posterior (Membranous and Prostatic)
   Fossa navicularis (1 to 1.5cms)
   Sump and Cone
   Cowper glands
   Urethral crest
   Verumontanum/Seminal colliculus
   Prostatic utricle
   Ejaculatory ducts
   Urethral sphincters
RETROGRADE URETHROGRAPHY
   Best initial study for urethral and periurethral imaging in men
   Evaluation of urethral injuries, strictures, and fistulas
   Contraindications
        Acute UTI
        Recent instrumentation
PROCEDURE
   The external meatus is prepared in a standard sterile fashion for the
    placement of a conventional 16-18F foley catheter
   The catheter, with both the irrigating syringe and inflating (saline
    solution) syringe attached, should be flushed before use.
   When the balloon portion of the catheter is seated in the fossa
    navicularis of the penile urethra, the balloon is inflated with 1.0–1.5 mL
    of saline solution while the port is held with the free hand to partially
    inflate the balloon
   Lubrication is not recommended because it may prevent the balloon
    from remaining in place for optimal occlusion
   The patient is placed in a supine 45° oblique position.
   The penis should be placed laterally over the proximal thigh with
    moderate traction
   Then, 20–30 mL of 60% iodinated contrast material is injected under
    fluoroscopic guidance so that the anterior urethra is filled
   Spot radiographs are obtained when there is visual confirmation of
    contrast material flowing into the bladder
MIMICS OF URETHRAL PATHOLOGY IN RGU
BLUNT URETHRAL TRAUMA
   Anterior urethral injury       Posterior urethral injury
    Straddle pelvic injury         Crushing force to the pelvic(pelvic
                                   fractures)
POSTERIOR URETHRAL INJURY
   Calpinto and Mccallum classification (for posterior urethral injuries)
   Goldman et al classification ( anterior + posterior urethral injuries)
   Complete disruption of membranous
    urethra, which occurs in both type II
    and type III urethral injury, may
    result in dislocation of bladder out of
    the pelvis, which appears as ‘PIE IN
    THE SKY’ at excretory urography
    (pelvic hematoma)
                ANTERIOR URETHRAL INJURY ( TYPE
                V)
   If the Buck fascia remains intact,
    the extravasation is limited to
    the space between the Buck
    fascia and the tunica albuginea
    of the corpus spongiosum.
   If the Buck fascia is
    ruptured,extravasation of
    contrast material will be present
    within the confines of the Colle
    fascia at urethrography
   Traumatic rupture of the female urethra is rare.
   Perry and Husmann found type IV urethral injuries in 4.6% of women
    with pelvic fracture caused by high-speed motor vehicle accidents.
   Late complications associated with
    posterior urethral injury include
    impotence, incontinence, stricture and
    fistula ,
   whereas those associated with anterior
    urethral injury include stricture and
    impotence.
               PENETRATING URETHRAL INJURIES
   Gun shots or knife wounds
   Commonly effect anterior urethra
ACQUIRED INFLAMMATORY DISEASES
   Gonococcal (N. gonnorhoeae) and Non Gonococcal urethritis
(C. trachomatis)
   Complications include urethral stricture, periurethral abscess, and
    periurethral fistulas
   Typical urethrographic findings in gonococcal urethral stricture is an
    irregular urethral narrowing which is several cms long
   Bulbar urethra is the most common area of occurence for the stricture
   Associated dilatation of Littre´ glands may be present at urethrography
CONDYLOMA ACUMINATA
    viral infection and produce soft, sessile,
     squamous papillomas (venereal warts)
    Urethral involvement occurs in 0.5%–5% of
     male patients.
    The diagnostic procedure of choice is voiding
     cystourethrography. However, the diagnosis is
     often not suspected until retrograde
     urethrography has been performed.
    The typical urethrographic findings are
     multiple papillary filling defects in the anterior
     urethra
                TUBERCULOSIS
   Very rare
   Prostatic abscess may rupture into any surrounding structure, which results in
    prostatorectal and prostatoperineal urethral fistulas.
   Tuberculous urethral strictures result in periurethral abscesses, which, unless treated,
    produce numerous perineal and scrotal fistulas.
   The end result is watering can perineum.
   Retrograde urethrography typically demonstrates an anterior urethral stricture
    associated with multiple prostatocutaneous and urethrocutaneous fistulas.
URETHRAL DIVERTICULA
   Penoscrotal region Is the most
    common site for urethral
    diverticula
   Due to repeated Urethral
    trauma due to cathetrisation
     URETHRAL CALCULI
   Migrant calculi.
   Occasionally,they get lodged at a point of
    urethral narrowing such as the
    membranous urethra.
   Primary (native) formation of a stone
    occurs in the urethra when stricture is
    present, or urethral diverticulum.
   RGU will usually depict a rounded filling
    defect in the urethra
Benign Tumors of the Urethra
1.   Leiomyoma
2.   Fibroepithelial polyps
        RGU will usually depict a smooth filling defect in the urethra
Malignant Tumors of the
Male Urethra
    The bulbomembranous urethra is
     involved most frequently (60%),
    80% are squamous cell carcinoma,
     15% are transitional cell carcinoma,
     and 5% are adenocarcinoma or
     undifferentiated carcinoma.
    RGU demonstrates focal irregular
     narrowing of the urethra
URETHRAL DISRUPTION AFTER
PANCREAS TRANSPLANTATION
   Bladder drainage of pancreatic graft exocrine secretions is a common
    technique in pancreas transplantation.
   Urethral injury and disruption, with urinary extravasation is attributed to
    activated proteolytic exocrine enzymes from the transplanted pancreas.
   RGU is the imaging method of choice in such cases
POST IRRADIATION URETHRAL
INJURIES
   Due to external radiation / prostatic brachytherapy
   Includes urethritis, urethral stricture, urethral fistula
COMPLICATIONS OF RGU
   Allergic reactions to contrast media
   UTI
   Urethral trauma/bleed
   Intravasation of Contrast