3 D PRINTING
Swati Mutha
Case study
• Syntratec FabRx—prepared oral formulation using 3 D
technique. First time investigated use of selective laser
sintering to make medicine.
• For making medicine , not used liquid binder but they
have used only powder and laser. First tablet prepared
with paracetamol after checked, it was noticed no drug
degradation. Then tried to prepared tablets with different
3D structures and release pattern by changing the
printing parameters like temperature, laser speed, tried
tablets with different strengths also.
• Focusing on preparing many more tablets with different
polymers for rare diseases
Steps of 3 D Printing
Modeling Printing Finishing
1
3
Detailed steps : Modeling:
1. Creation
• 3 D Modeling Design softwares :
• like Blender, SketchUp, AutoCad, SolidWorks, Maya, PhotoShop, ThinkerCad
• 3D scanning:
• is a technology, closely related to 3D printing, that analyses a real-world object
and instantly creates a digital replica. 3D Scanning is widely used for reverse
engineering tasks from industry professionals.
• 3 D Print ready files :
• websites like Thingivers, YouMagine, CrabCad, and MyMinifactory
Shapeways used to download or buy files that other users have modeled.
• When designing for Additive Manufacturing (3D Printing), we need to keep
in mind major things like proper scale-size, minimum wall thickness,
manifold etc
2. STL
• First, we need to convert it into an appropriate file format. The
most common 3D Printing file format is called STL, that stands
for STereoLithography, and named after the first ever 3D
printing process. STL has several other meanings such as
“Standard Triangle Language” and “Standard Tessellation
Language”. What is important to remember here is that .STL is
the usable file extension.
• This file format includes triangular mesh (polygons), the data
that describes the layout/surface of a three-dimensional object
• All those file formats don’t contain color information. For 3D
printing in full color, you need to use file formats
like .X3D, .WRL, .DAE, .PLY
• 3. Slicing:
• The process of translating the 3D File into instructions for the
3D printer to follow.
• Slicing is dividing or chopping the 3D model into hundreds or
thousands of horizontal layers, telling the machine exactly what
to do, step by step. After the files are Sliced, a new file format
is generated called G-code
• Basically G-code is the language of the machine and what we
use to communicate with it
•4. Choose Materials
•Typically we may have an idea about what kind of material we
will use before we print. There are many different 3D printing
materials available, and we can choose them based on the
properties that we want your object to have.
•5. Select Parameters
•Printing speed, layer thickness, temperature
Printing
• Most 3D Printers do not need to be monitored after the
printing has begun. The machine will follow the automated G-
code instructions, so as long as there is no software error or
the machine doesn’t run out of raw material, there should not
be a issues during the printing process
Finishing
• For some industrial 3D printers, the removal of a part is a
technical process that requires professional skills and
specialized equipment within a controlled environment.
• Post-processing is an important step for the aesthetic and
function of the parts.
• In the majority of cases 3D printed parts are rough and do not
have finished feel but can be vastly improved with the right
techniques and craftsmanship
Imp video link
• First FDA aproved 3D printed Drug Spritam
• https://www.youtube.com/watch?v=pDAT2PhI1mg
• SLS is used to 3D print personalized Medicine – FabRx
Customer Story
• https://www.youtube.com/watch?v=ePVFasXDi68
