permeability-jobs-in-palakkad, Palakkad

7 Permeability Jobs nearby Palakkad

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posted 2 weeks ago
experience3 to 7 Yrs
location
All India
skills
  • In Vitro ADME
  • In Vitro Stability
  • CYP Induction
  • CYP Inhibition Assays
  • Permeability Determinations
  • CYP Phenotyping
  • Solubility Determinations
Job Description
As a Research Associate II - In Vitro, ADME at Jubilant Biosys in Bengaluru, your role involves reading and understanding various in vitro ADME protocols. You will be responsible for conducting in vitro stability experiments for new chemical entities in liver microsomes, plasma, and other relevant matrices. Additionally, you will conduct various in vitro ADME experiments including logP, logD, and pKa measurements, CYP induction and inhibition assays, permeability determinations in relevant cell lines such as Caco-2 and MDCK, CYP phenotyping in purified enzyme systems, and solubility determinations in kinetic, thermodynamic, and simulated fluids. Qualification Required: - M.Pharmacy Experience Required: - 3-5 years You will play a crucial role in conducting a variety of in vitro ADME experiments and contributing to the research and development efforts at Jubilant Biosys. As a Research Associate II - In Vitro, ADME at Jubilant Biosys in Bengaluru, your role involves reading and understanding various in vitro ADME protocols. You will be responsible for conducting in vitro stability experiments for new chemical entities in liver microsomes, plasma, and other relevant matrices. Additionally, you will conduct various in vitro ADME experiments including logP, logD, and pKa measurements, CYP induction and inhibition assays, permeability determinations in relevant cell lines such as Caco-2 and MDCK, CYP phenotyping in purified enzyme systems, and solubility determinations in kinetic, thermodynamic, and simulated fluids. Qualification Required: - M.Pharmacy Experience Required: - 3-5 years You will play a crucial role in conducting a variety of in vitro ADME experiments and contributing to the research and development efforts at Jubilant Biosys.
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posted 1 week ago

Reservoir Engineer

AYURSMITH WELLNESS (OPC) PRIVATE LIMITED
experience13 to 23 Yrs
Salary10 - 22 LPA
WorkContractual
location
Australia
skills
  • facility administration
  • facility operations
  • reservoir engineering
  • reservoir evaluation
  • reservoir management
  • reservoir geology
  • facilities management
  • reserve estimation
  • petroleum economics
  • engineer
  • reservoir
Job Description
Reservoir engineering is a branch of petroleum engineering that applies scientific principles to manage oil and gas reservoirs for maximum economic recovery. It involves evaluating reservoir performance, modeling fluid flow, and optimizing production by understanding properties like porosity and permeability. Key tasks include determining the number and placement of wells and managing pressure to increase hydrocarbon output while minimizing costs The Reservoir Engineer is responsible for analyzing and assessing oil and gas reservoirs to maximize their extraction for use in the energy industry. They must possess a strong background in geology, engineering, and computer technology, as well as the ability to work collaboratively with other teams to ensure efficient and effective operation of oil and gas reservoirs. The Reservoir Engineer will be responsible for evaluating oil and gas reserves, optimizing production levels, and monitoring field performance. The candidate will also be responsible for generating reservoir models and providing technical recommendations for reservoir management. Key Responsibilities Perform reservoir simulations and analysis to evaluate potential oil and gas recovery Develop and implement reservoir management strategies to optimize production Evaluate and recommend drilling and completion techniques to enhance productivity Analyze well and reservoir performance to identify opportunities for improvement Generate and maintain reservoir models to monitor and forecast production Collaborate with multidisciplinary teams to ensure reservoir development and production goals are met Provide technical expertise to support business development activities Conduct technical presentations to share results and recommendations with stakeholders
posted 2 weeks ago
experience0 to 4 Yrs
location
Maharashtra
skills
  • Mechanical Engineering
  • Aerospace Engineering
  • Materials Engineering
  • Manufacturing Engineering
  • Research
  • Academic Research
  • Teamwork
  • Interpersonal Skills
  • Health
  • Safety
  • Publication
  • Conference Presentation
Job Description
As a Research Associate (Level A) at UNSW School of Mechanical and Manufacturing Engineering in Sydney, Australia, you will have the opportunity to contribute to cutting-edge research in the field of Advanced Manufacturing of MOF-Enabled Carbon Composite H2 Tanks for Heavy Mobility as part of the Australian Composite Manufacturing Cooperative Research Centre (ACM CRC) project. Your role will involve working within an interdisciplinary team to advance technologies for hydrogen storage materials and lightweight composite storage vessels. Key Responsibilities: - Contribute to the development of full-system models of MOF-enabled hydrogen storage tanks under cryo-compressed conditions - Progress R&D relevant to large format composite and metallic hydrogen storage tanks, focusing on impact damage prediction and permeability characterisation - Collaborate with end users and certification bodies to advance the technology readiness level (TRL) and certification pathways for novel hydrogen tanks Qualifications Required: - Hold a PhD (or equivalent) in a related discipline such as Mechanical, Aerospace, Materials, or Manufacturing Engineering - Demonstrate a proactive approach to staying updated with discipline knowledge and developments - Exhibit the ability to conduct high-quality academic research independently with limited supervision - Showcase a track record of publications and conference presentations relevant to the opportunity - Possess strong interpersonal skills and the ability to work in a team, collaborate across disciplines, and build effective relationships - Show evidence of effective communication and interaction with a diverse range of stakeholders and students - Demonstrate an understanding of and commitment to UNSW's aims, objectives, values, and relevant policies - Have knowledge of health and safety responsibilities and a commitment to attending relevant health and safety training About UNSW: UNSW is a unique and driven community that values thoughtfulness, practicality, and purpose in all endeavors. By joining UNSW, you will have the opportunity to thrive, be challenged, and engage in meaningful work within a diverse and talented environment. Please note that applicants must have valid working rights in Australia, as visa sponsorship is not available for this position. Applications must be submitted online by the specified deadline, and further details about the position can be found in the official position description available via JOBS@UNSW. If you are interested in this exciting research opportunity, please click the apply now button and submit your CV, Cover Letter, and Responses to the Skills and Experience as outlined in the position description. Applications sent to the listed contact will not be considered. Application Deadline: 11:55 pm (Sydney time) on Thursday 4th December 2025,
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posted 2 months ago
experience3 to 7 Yrs
location
Siliguri, West Bengal
skills
  • Interpreting data
  • AutoCAD
  • Feasibility studies
  • Geological mapping
  • Surveying
  • Project management
  • Geotechnical tests
  • HSE policies
  • Grouting techniques
Job Description
As a Geologist-Manager/Officer at HCI-Heavy Civil Infrastructure in Siliguri & North Bengal, your role will involve performing geotechnical tests such as packer permeability tests in bore logs, interpreting geotechnical instrumentation data, and working on projects related to Hydel, Tunnel, Dams, Barrage, Pump Storage, among others. You will be responsible for planning and designing construction methodologies for underground projects, conducting feasibility studies, preparing geological mapping, sections, and plans using AutoCAD, and assisting in the selection of project sites. - Perform geotechnical tests in bore logs like packer permeability tests. - Interpret data from geotechnical instrumentation such as SPBX, MPBX, Load cell, Piezometer. - Work on projects related to Hydel & Tunnel, Dams, Barrage, Pump Storage. - Assist in planning and designing construction methodologies for underground projects. - Prepare feasibility studies and technical geological mapping. - Plot geological sections and plans on real earth coordinates using AutoCAD. - Conduct detailed surveys for tunnel design and site selection. - Manage daily and monthly progress reporting, project works monitoring, and reviews. - Maintain records of design/construction drawings for the entire project. - Coordinate with clients and local stakeholders for project scope. - Assist in the preparation of monthly bills and quantity calculations. - Conduct investigations and construction activities for underground structures using various logging and testing techniques. - Ensure compliance with HSE, EMS, and QMS policies as per company standards. - Document geological database according to IMS and ISO guidelines. - Implement grouting techniques such as Jet, Consolidation, and Contact Grouting. - Lead and manage the team of engineers to deliver high-quality work within specified timelines. - MSC or BSC in Geology or related field.,
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posted 7 days ago

QC Head (CRGO)

Vilas Transcore Limited
experience10 to 14 Yrs
location
Gujarat, Vadodara
skills
  • quality control
  • management
  • customer
  • steel
  • documentation
  • manufacturing
Job Description
Role Overview: As the Head of Quality Control (QC) at our CRGO Steel Manufacturing / Electrical Steel facility in Vadodara, your primary responsibility is to lead the Quality Control department. Your role involves ensuring that all CRGO products meet both national and international quality standards. You will oversee various aspects such as testing, inspection, process audits, documentation, and compliance to guarantee a consistent output of high-performance CRGO materials for the transformer and electrical industry. Key Responsibilities: - Develop and implement quality control procedures specific to CRGO steel processing, including slitting, annealing, coating, cutting, etc. - Monitor the quality of incoming raw material, in-process material, and finished goods. - Ensure adherence to ISO, BIS, IEC, and other relevant standards for electrical steel. - Oversee mechanical, electrical, and chemical testing of CRGO materials, including core loss, magnetic permeability, thickness, surface insulation resistance, and coating adhesion. - Ensure calibration and maintenance of testing equipment such as Epstein testers, Franklin testers, etc. - Conduct regular audits of manufacturing processes to ensure compliance and identify areas for improvement. - Analyze quality trends, reject rates, and customer complaints to initiate corrective and preventive actions (CAPA). - Work with production and R&D teams for process optimization and new product trials. - Maintain all required documentation for traceability, certifications, and compliance audits. - Lead efforts to achieve and maintain ISO 9001, ISO 14001, or IATF certifications. - Prepare quality reports and present findings to senior management. - Handle technical quality queries and complaints from customers (OEMs, transformer manufacturers). - Coordinate third-party inspections and testing when required. - Support sales/marketing with technical certifications and product data sheets. - Lead and mentor the QC/QA team. - Plan training programs to ensure the team is updated on the latest standards and testing protocols. Qualification Required: - 10+ years of experience in quality control within the CRGO or specialty steel industry. - Skills in quality control, management, customer service, steel manufacturing, and documentation. (Note: No additional details of the company are mentioned in the provided job description),
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posted 1 week ago

Pharmacologist

PI Health Sciences Ltd
experience6 to 10 Yrs
location
Hyderabad, Telangana
skills
  • Pharmacology
  • Biochemistry
  • Pharmaceutical Sciences
  • ADME
  • Solubility
  • Automation Tools
  • LCMSMS
  • Metabolic Stability
  • Plasma Stability
  • Protein Binding
  • CYP Inhibition
  • Phenotyping
  • PAMPA
  • Caco2
  • MDCK
  • Transporter Assays
  • DDI Workflows
  • IVIVE
  • ADMET Modelling
  • ELNs
  • SOP Drafting
  • LCMSMS Operations
Job Description
As a Research Scientist - In Vitro ADME, your primary role is to generate high-quality and reproducible in-vitro ADME data to support medicinal chemistry and discovery biology teams in optimizing molecular properties. This involves robust ADME assay execution, scientific interpretation, innovation in assay methodologies, and effective cross-functional collaboration to accelerate hit-to-lead and lead optimization programs. Key Responsibilities: - Provide strategic ADME insights to Medicinal Chemistry and Biology for compound prioritization. - Influence project direction by interpreting trends in clearance, permeability, solubility, DDI risk, and transporter interactions. - Contribute to defining the ADME package for hit-to-lead, lead optimization, and early preclinical milestones. - Identify and introduce emerging ADME assay technologies, automation opportunities, and predictive tools (e.g., IVIVE, ADMET modelling). - Support long-term capability building of the DMPK platform. Operational Responsibilities: - Independently design, execute, and troubleshoot in-vitro ADME assays such as metabolic stability, plasma stability, protein binding, CYP inhibition/induction, phenotyping, PAMPA, Caco-2, MDCK, transporter assays, solubility, and DDI workflows. - Analyse and interpret LC-MS/MS data to calculate intrinsic clearance, permeability coefficients, efflux ratios, enzyme contributions, and stability parameters. - Maintain meticulous documentation through ELNs, assay worksheets, and technical reports. - Coordinate with cross-functional teams for sample management, study timelines, and data delivery. - Maintain lab infrastructure including LC-MS/MS, automation systems (TECAN), incubators, and cell culture platforms. - Support assay validation, SOP drafting, and continuous improvement initiatives. Financial Responsibilities: - Optimize usage of consumables, enzymes, reagents, plates, and solvents to minimize assay costs. - Ensure efficient LC-MS/MS run scheduling to maximize instrument throughput and reduce operational overheads. - Contribute to budgeting for ADME assays, method development projects, and instrument maintenance needs. - Avoid repeat experiments through strong assay robustness and error-free execution. People Responsibilities: - Mentor junior team members on ADME assay execution, data analysis, and instrument handling. - Foster a culture of scientific rigor, collaboration, and knowledge sharing across the discovery teams. - Provide training on new assays, safety practices, LC-MS/MS operations, and automation tools. - Demonstrate collaboration with Medicinal Chemistry, Biology, and PK/PD teams by ensuring timely delivery of ADME insights. Risk & Compliance Responsibilities: - Ensure adherence to internal SOPs, quality standards, and audit requirements. - Follow all safety guidelines related to chemical handling, biohazards, waste disposal, and lab operations. - Conduct periodic instrument checks, calibration, and preventive maintenance to avoid operational risks. - Maintain strict data integrity (ALCOA+), traceability, and documentation discipline. - Flag scientific, operational, or compliance risks (e.g., assay drift, QC failures) proactively.,
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posted 1 week ago
experience7 to 15 Yrs
location
Hyderabad, Telangana
skills
  • Pharmaceutical Industry
  • Analytical Chemistry
  • Organic Chemistry
  • Scientific Writing
  • Regulatory Requirements
  • Project Management
  • Complex Generics
  • Inhalation Products
  • PharmaceuticalFormulation
  • Product Characterizations
Job Description
Role Overview: As a Senior Scientist I/II at the U.S. Pharmacopeial Convention (USP), you will be responsible for a non-supervisory, hands-on, highly technical role supporting the standard-setting activities of the USP-NF. Your primary focus will be on revising and developing new USP standards and standards associated with complex generics while working closely with USPs Expert Committees. Your contributions will play a vital role in increasing global access to high-quality medicines through public standards and related programs. Key Responsibilities: - Describe, build, and advance a vision and roadmap for Complex Generics, with a focus on Inhalation products. - Participate in cross-functional groups to focus efforts on specific knowledge domains and high-impact topics. - Determine deliverables, requirements, and timelines for the development of standards and solutions for complex generics particularly, inhalation products. - Execute against the standards and solutions roadmap through tight integration of activities within USP and with external stakeholders, including but not limited to industry, academia, and regulators. - Advocate for inhalation product development to support the generic pharmaceutical industry and use of USP standards and solutions across the broader scientific and regulatory communities. - Maintain awareness of the current trends and issues in the industry by attending scientific seminars, conferences, industry consortia meetings, and other fora. - Represent USP science and standards at industry conferences and symposia as well as through written articles. - Work closely with other USP departments to ensure Complex Generics related standards and solutions are known, valued, and used through various service offerings such as education and training, consulting, and lab services. - Participate in internal and external capability-building activities related to Complex Generics, including training, education, and knowledge-sharing across the organization. - Perform any other duties as assigned. Qualifications Required: For Senior Scientist - I: - Ph.D. degree in Organic, Analytical, Pharmaceutical/Formulation, or a related field and a minimum of 7-10 years, or M.Sc./M.Pharm with a minimum of 11-13 years of relevant experience with USP-NF test and standards is required. For Senior Scientist - II: - Ph.D. degree in Analytical Chemistry, Organic Chemistry, Pharmaceutical/Formulation, or a related field and a minimum of 10-13 years, or M.Sc./M.Pharm. with a minimum of 13-15 years of relevant experience with USP-NF test and standards is required. - Direct, practical experience in the Complex Generics field in the pharmaceutical industry, with a focus on inhalation products as well as other complex product expertise such as ophthalmics and /or complex injectables. - In-depth knowledge of various product characterizations for inhalation products including particle size analysis, spray pattern, and plume geometry, dissolution and permeability, delivered dose and aerodynamic sizing, fine particle fraction, and others. - Excellent written and verbal communication skills with a focus on scientific writing for the pharmaceutical industry. - Strong interpersonal and relationship-building skills. Company Details: The U.S. Pharmacopeial Convention (USP) is an independent scientific organization dedicated to collaborating with leading health and science experts to develop quality standards for medicines, dietary supplements, and food ingredients. USP values inclusive scientific collaboration and is committed to ensuring fair and merit-based selection processes for all individuals, regardless of background. USP provides reasonable accommodations to individuals with disabilities and upholds policies that create an inclusive and collaborative work environment.,
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