Managing Anaphylaxis at School
Sabrina Shannon had a severe allergy to peanuts, dairy & soy products Sabrina was 13 when she died after eating french fries at school that had been cross-contaminated with cheese – thought to be an asthma attack at first Sabrina’s Law - (the first of its’ kind in the world) is intended to protect students at school with life-threatening allergies It came into effect January 1, 2006. Sabrina’s Law – Bill 3
Sabrina’s Law – Bill 3   Click here to view The law states that school boards must establish and maintain a policy on anaphylaxis with: ways to reduce risk of exposure a communication plan regular training an individual plan for each student with anaphylaxis a file for each anaphylactic student with: details on the type of allergy monitoring and avoidance strategies and appropriate treatment a readily accessible emergency procedure for the student storage for epinephrine auto-injectors
What is Anaphylaxis? a sudden & severe allergic reaction involving one or more body systems with multiple symptoms possible a condition that requires immediate attention and treatment 1~2% of Canadians a growing problem estimated that ~5% of adult population has experienced it and is on the rise (U.S. data) deaths in Ontario from anaphylaxis are not increasing however (Anaphylaxis Canada)
Common Triggers Foods   33-55%  (peanuts, tree nuts, shellfish & fish, milk, soy, sesame seed, sulphites [ wine, dried fruits & dried potatoes ], wheat and eggs) Highest in younger children (6-8% infants have a food allergy) Insect stings  (bees, wasps, yellow jackets, other biting insects) Medications  (75% Penicillin, non-steroidal anti-inflammatory [Aspirin], vaccines, + many others) Latex  (balloons, elastics, bandages etc…) Exercise
What to Look for While Eating: Itching in and around the mouth is often the first symptom observed in people experiencing food-induced anaphylaxis Commonly & quickly progresses into cramps, nausea, vomiting and diarrhea and/or breathing problems Students with asthma are at greater risk ~10% of children with asthma have  food  allergy ~10% of children in Canada have asthma very likely there are students with unidentified anaphylaxis in most schools
What Anaphylaxis Looks Like: Source  http://www.anaphylaxis.com/   Signs / symptoms Incidence (%) Hives and swelling of skin 88 Upper airway swelling (throat tightening) 56 Difficulty breathing + wheezing 47 Flush 46 Dizziness, fainting, low BP (weak pulse) 33 Nausea, vomiting, cramps 30 Sneezing, runny nose, watery eyes 16 Headache 15 Pain below the ribcage 6 Itch without rash 4.5 Seizure 1.5 Others (metallic taste, sense of impending doom / anxiety / panic) ?
Common Myths vs. Facts Source  http://www.anaphylaxis.com/   Myth Anaphylaxis is rare Cause is always known It will always show on the skin Previous reactions will predict subsequent ones Epinephrine is dangerous Anaphylaxis is reported It is easy to avoid if you know what you are allergic to Reality Anaphylaxis is underreported Cause is usually unexplainable 10-20% of cases show no sign of hives or other skin indications 80% of food-induced, fatal anaphylaxis cases were not associated with skin related signs or symptoms There is no predictable pattern –  depends on dose of allergen and individual sensitivity Benefits far outweigh the risks Most people don’t report it Most cases are due to accidental exposure
Preventing Anaphylaxis Awareness know causes and triggers emergency plan promoting awareness in the entire school community e.g. medic-alert bracelets labeling practices can be much less stringent outside North America e.g. chocolate from eastern Europe with undeclared peanut protein interpreting labels can be tricky e.g. ovalbumin for egg derivatives, whey or casein for milk ingredients some allergens are still exempt from declaration e.g. sulphites
Avoidance avoid contact with allergen create an allergen safe environment: avoid using outdoor garbage cans, ensure proper footwear, use latex-free products  avoid sharing of lunches, snacks, and utensils avoid bulk foods avoid cross-contamination (sanitation & hand washing) Preventing Anaphylaxis
Action administer epinephrine immediately (even if only suspected) access emergency medical treatment – call ASAP position student so breathing is comfortable  always send student to hospital even if symptoms resolve Preventing Anaphylaxis
Epinephrine Epinephrine by injection is the treatment of choice for anaphylactic reactions Epinephrine works quickly to: improve breathing & open airways stimulate the heart constrict blood vessels (maintains blood pressure & directs blood flow to major organs) reverse hives and swelling around the face & lips There are  no identified contraindications  to the use of epinephrine in life-threatening allergic reactions in an otherwise healthy child
Epinephrine Auto-Injectors Auto-injectors are disposable, prefilled devices that automatically administer a single dose of epinephrine for the emergency treatment of anaphylaxis Twinject®  and  EpiPen ®  are the two brands available in Canada
Different Doses Epinephrine dosing is based on body weight There are 2 dosage strengths: EpiPen® Jr. (green) / Twinject® 0.15 mg  for individuals weighing  15-30 kg (33-66 lbs)   EpiPen® (yellow) / Twinject®  0.30 mg  for individuals weighing  30 kg+ (66 lbs+)
EpiPen® Grasp the auto-injector with the BLACK tip pointing down Pull off the safety cap Swing and jab BLACK tip firmly into outer thigh so it “clicks” and hold for 10 seconds Remove EpiPen® and massage injected area If needle and red plunger are showing - dose has been delivered Call 911 if not already initiated Return syringe to case Click here for online video instructions
Twinject®   Contains 2 separate doses of epinephrine First dose delivered by auto-injector Second dose delivered manually by syringe   Click here for online video instructions
Twinject® - First Dose Remove Injector from case Grasp needle with one hand Pull off  GREEN  Caps  1  &  2 Jab  RED  tip of syringe firmly against outer mid-thigh and hold for 10 seconds remove Twinject®  and m assage injected area If needle is showing – dose was delivered Call 911 if not already initiated Return syringe to case
Second Dose An extra dose of epinephrine should always be available (World Health Organization) Schools are being directed to use the EpiPen ®  for the second dose Use second dose if symptoms do not subside within 5-10 minutes or reoccur More than 1/3 will require a second dose of epinephrine
Tips For Using Auto-Injectors Never put fingers over the tip when removing the safety cap, or after the safety cap has been removed Keep auto-injectors at room temperature and readily available  Occasionally inspect the solution through the viewing window, if it looks brown, cloudy or containing sediment - have it replaced (should be mostly clear & colourless) Check expiry dates Auto-injectors can be used directly through clothing Bend the needle on a hard surface after removing and return to case Send used injectors with patient (in case provided)
For More Information Anaphylaxis Canada www.anaphylaxis.org "Back to School: how to manage allergies safely“ - online podcast available on website starting on August 26th, 2009 Action Steps for Anaphylaxis Management http://www.allergysafecommunities.ca/assets/appendix_b_eng.pdf   MOE Self-Learning Module for Teachers www.eworkshop.on.ca/allergies Allergy/Asthma Information Association  www.aaia.ca Canadian Society of Allergy and Clinical Immunology www.csaci.ca
EpiPen®   -   To Order Training Material / Resources http://www.epipen.ca/   Twinject®  -   To Order Training Material / Resources http://www.twinject.ca/ Health Canada  – Allergen Labeling http://www.hc-sc.gc.ca/fn-an/label-etiquet/allergen/index-eng.php   For More Information

Anaphylaxis

  • 1.
  • 2.
    Sabrina Shannon hada severe allergy to peanuts, dairy & soy products Sabrina was 13 when she died after eating french fries at school that had been cross-contaminated with cheese – thought to be an asthma attack at first Sabrina’s Law - (the first of its’ kind in the world) is intended to protect students at school with life-threatening allergies It came into effect January 1, 2006. Sabrina’s Law – Bill 3
  • 3.
    Sabrina’s Law –Bill 3 Click here to view The law states that school boards must establish and maintain a policy on anaphylaxis with: ways to reduce risk of exposure a communication plan regular training an individual plan for each student with anaphylaxis a file for each anaphylactic student with: details on the type of allergy monitoring and avoidance strategies and appropriate treatment a readily accessible emergency procedure for the student storage for epinephrine auto-injectors
  • 4.
    What is Anaphylaxis?a sudden & severe allergic reaction involving one or more body systems with multiple symptoms possible a condition that requires immediate attention and treatment 1~2% of Canadians a growing problem estimated that ~5% of adult population has experienced it and is on the rise (U.S. data) deaths in Ontario from anaphylaxis are not increasing however (Anaphylaxis Canada)
  • 5.
    Common Triggers Foods 33-55% (peanuts, tree nuts, shellfish & fish, milk, soy, sesame seed, sulphites [ wine, dried fruits & dried potatoes ], wheat and eggs) Highest in younger children (6-8% infants have a food allergy) Insect stings (bees, wasps, yellow jackets, other biting insects) Medications (75% Penicillin, non-steroidal anti-inflammatory [Aspirin], vaccines, + many others) Latex (balloons, elastics, bandages etc…) Exercise
  • 6.
    What to Lookfor While Eating: Itching in and around the mouth is often the first symptom observed in people experiencing food-induced anaphylaxis Commonly & quickly progresses into cramps, nausea, vomiting and diarrhea and/or breathing problems Students with asthma are at greater risk ~10% of children with asthma have food allergy ~10% of children in Canada have asthma very likely there are students with unidentified anaphylaxis in most schools
  • 7.
    What Anaphylaxis LooksLike: Source http://www.anaphylaxis.com/ Signs / symptoms Incidence (%) Hives and swelling of skin 88 Upper airway swelling (throat tightening) 56 Difficulty breathing + wheezing 47 Flush 46 Dizziness, fainting, low BP (weak pulse) 33 Nausea, vomiting, cramps 30 Sneezing, runny nose, watery eyes 16 Headache 15 Pain below the ribcage 6 Itch without rash 4.5 Seizure 1.5 Others (metallic taste, sense of impending doom / anxiety / panic) ?
  • 8.
    Common Myths vs.Facts Source http://www.anaphylaxis.com/ Myth Anaphylaxis is rare Cause is always known It will always show on the skin Previous reactions will predict subsequent ones Epinephrine is dangerous Anaphylaxis is reported It is easy to avoid if you know what you are allergic to Reality Anaphylaxis is underreported Cause is usually unexplainable 10-20% of cases show no sign of hives or other skin indications 80% of food-induced, fatal anaphylaxis cases were not associated with skin related signs or symptoms There is no predictable pattern – depends on dose of allergen and individual sensitivity Benefits far outweigh the risks Most people don’t report it Most cases are due to accidental exposure
  • 9.
    Preventing Anaphylaxis Awarenessknow causes and triggers emergency plan promoting awareness in the entire school community e.g. medic-alert bracelets labeling practices can be much less stringent outside North America e.g. chocolate from eastern Europe with undeclared peanut protein interpreting labels can be tricky e.g. ovalbumin for egg derivatives, whey or casein for milk ingredients some allergens are still exempt from declaration e.g. sulphites
  • 10.
    Avoidance avoid contactwith allergen create an allergen safe environment: avoid using outdoor garbage cans, ensure proper footwear, use latex-free products avoid sharing of lunches, snacks, and utensils avoid bulk foods avoid cross-contamination (sanitation & hand washing) Preventing Anaphylaxis
  • 11.
    Action administer epinephrineimmediately (even if only suspected) access emergency medical treatment – call ASAP position student so breathing is comfortable always send student to hospital even if symptoms resolve Preventing Anaphylaxis
  • 12.
    Epinephrine Epinephrine byinjection is the treatment of choice for anaphylactic reactions Epinephrine works quickly to: improve breathing & open airways stimulate the heart constrict blood vessels (maintains blood pressure & directs blood flow to major organs) reverse hives and swelling around the face & lips There are no identified contraindications to the use of epinephrine in life-threatening allergic reactions in an otherwise healthy child
  • 13.
    Epinephrine Auto-Injectors Auto-injectorsare disposable, prefilled devices that automatically administer a single dose of epinephrine for the emergency treatment of anaphylaxis Twinject® and EpiPen ® are the two brands available in Canada
  • 14.
    Different Doses Epinephrinedosing is based on body weight There are 2 dosage strengths: EpiPen® Jr. (green) / Twinject® 0.15 mg for individuals weighing 15-30 kg (33-66 lbs) EpiPen® (yellow) / Twinject® 0.30 mg for individuals weighing 30 kg+ (66 lbs+)
  • 15.
    EpiPen® Grasp theauto-injector with the BLACK tip pointing down Pull off the safety cap Swing and jab BLACK tip firmly into outer thigh so it “clicks” and hold for 10 seconds Remove EpiPen® and massage injected area If needle and red plunger are showing - dose has been delivered Call 911 if not already initiated Return syringe to case Click here for online video instructions
  • 16.
    Twinject® Contains 2 separate doses of epinephrine First dose delivered by auto-injector Second dose delivered manually by syringe Click here for online video instructions
  • 17.
    Twinject® - FirstDose Remove Injector from case Grasp needle with one hand Pull off GREEN Caps 1 & 2 Jab RED tip of syringe firmly against outer mid-thigh and hold for 10 seconds remove Twinject® and m assage injected area If needle is showing – dose was delivered Call 911 if not already initiated Return syringe to case
  • 18.
    Second Dose Anextra dose of epinephrine should always be available (World Health Organization) Schools are being directed to use the EpiPen ® for the second dose Use second dose if symptoms do not subside within 5-10 minutes or reoccur More than 1/3 will require a second dose of epinephrine
  • 19.
    Tips For UsingAuto-Injectors Never put fingers over the tip when removing the safety cap, or after the safety cap has been removed Keep auto-injectors at room temperature and readily available Occasionally inspect the solution through the viewing window, if it looks brown, cloudy or containing sediment - have it replaced (should be mostly clear & colourless) Check expiry dates Auto-injectors can be used directly through clothing Bend the needle on a hard surface after removing and return to case Send used injectors with patient (in case provided)
  • 20.
    For More InformationAnaphylaxis Canada www.anaphylaxis.org "Back to School: how to manage allergies safely“ - online podcast available on website starting on August 26th, 2009 Action Steps for Anaphylaxis Management http://www.allergysafecommunities.ca/assets/appendix_b_eng.pdf MOE Self-Learning Module for Teachers www.eworkshop.on.ca/allergies Allergy/Asthma Information Association www.aaia.ca Canadian Society of Allergy and Clinical Immunology www.csaci.ca
  • 21.
    EpiPen® - To Order Training Material / Resources http://www.epipen.ca/ Twinject® - To Order Training Material / Resources http://www.twinject.ca/ Health Canada – Allergen Labeling http://www.hc-sc.gc.ca/fn-an/label-etiquet/allergen/index-eng.php For More Information

Editor's Notes

  • #8 This table summarizes the presenting signs and symptoms documented in 4 studies involving 743 patients with anaphylaxis. The most common symptoms were urticaria and angioedema, occurring in 88% of patients. The next most common manifestations were respiratory symptoms, such as upper airway edema, dyspnea, and wheezing. Cardiovascular symptoms of dizziness, syncope, and hypotension, were less common, but it is important to remember that cardiovascular collapse may occur abruptly, without the prior development of skin or respiratory manifestations. Other symptoms of rhinitis, headache, substernal pain, and pruritus without rash were less commonly observed. Lieberman P. Distinguishing anaphylaxis from other serious disorders. J Respir Dis 1995;16:411–420.