Myeloid differentiation primary response gene 88 (Q14905922)

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mammalian protein found in Mus musculus

myeloid differentiation primary response protein 88
myeloid differentiation primary response protein MyD88
uniprot:P22366
Myd88

Language	Label	Description	Also known as
English	Myeloid differentiation primary response gene 88	mammalian protein found in Mus musculus	myeloid differentiation primary response protein 88 myeloid differentiation primary response protein MyD88 uniprot:P22366 Myd88

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Myeloid differentiation primary response protein MyD88

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22366

Toll/interleukin-1 receptor homology (TIR) domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22366

Death-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22366

Death domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

MyD88, death domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Toll/interleukin-1 receptor homology (TIR) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method or standard

18 references

9 May 2019

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Negative regulation of Toll-like-receptor signaling by IRF-4.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

identical protein binding

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

determination method or standard

1 reference

9 May 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22366

determination method or standard

signaling receptor binding

determination method or standard

1 reference

9 May 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22366

determination method or standard

interleukin-1 receptor binding

determination method or standard

1 reference

9 May 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22366

determination method or standard

protein self-association

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

Toll-like receptor binding

determination method or standard

1 reference

8 April 2019

The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

determination method or standard

1 reference

9 May 2019

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

plasma membrane

determination method or standard

1 reference

8 April 2019

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

determination method or standard

1 reference

16 September 2017

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22366&geneProductId=UniProtKB:P22366

determination method or standard

determination method or standard

3 references

9 May 2019

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

postsynaptic density

determination method or standard

1 reference

16 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22366&geneProductId=UniProtKB:P22366

determination method or standard

biological process

response to interleukin-1

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

establishment of endothelial intestinal barrier

determination method or standard

1 reference

9 May 2019

Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

regulation of chemokine (C-X-C motif) ligand 1 production

determination method or standard

1 reference

9 May 2019

MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

regulation of tumor necrosis factor production

determination method or standard

1 reference

9 May 2019

MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

immune system process

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

positive regulation of JNK cascade

determination method or standard

1 reference

9 May 2019

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

regulation of neutrophil migration

determination method or standard

1 reference

9 May 2019

MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

cell surface receptor signaling pathway

determination method or standard

1 reference

9 May 2019

Dectin-1 mediates the biological effects of beta-glucans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

response to lipopolysaccharide

determination method or standard

5 references

9 May 2019

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Dectin-1 mediates the biological effects of beta-glucans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

response to molecule of fungal origin

determination method or standard

1 reference

9 May 2019

Dectin-1 mediates the biological effects of beta-glucans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

transmembrane receptor protein serine/threonine kinase signaling pathway

determination method or standard

1 reference

9 May 2019

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

regulation of cell population proliferation

determination method or standard

1 reference

9 May 2019

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

immunoglobulin mediated immune response

determination method or standard

1 reference

9 May 2019

IRF-7 is the master regulator of type-I interferon-dependent immune responses

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

response to peptidoglycan

determination method or standard

1 reference

9 May 2019

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

immune response

determination method or standard

1 reference

9 May 2019

TIRAP: an adapter molecule in the Toll signaling pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

regulation of inflammatory response

determination method or standard

1 reference

9 May 2019

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

induced systemic resistance

determination method or standard

1 reference

9 May 2019

MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

positive regulation of interleukin-6 production

determination method or standard

positive regulation of tumor necrosis factor production

determination method or standard

5 references

9 May 2019

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Dectin-1 mediates the biological effects of beta-glucans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

regulation of gene expression

determination method or standard

1 reference

9 May 2019

Involvement of heat shock protein (Hsp)90 beta but not Hsp90 alpha in antiapoptotic effect of CpG-B oligodeoxynucleotide

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

positive regulation of interleukin-17 production

determination method or standard

1 reference

9 May 2019

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

innate immune response

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

3'-UTR-mediated mRNA stabilization

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

positive regulation of lymphocyte proliferation

determination method or standard

1 reference

9 May 2019

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

positive regulation of type I interferon production

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

positive regulation of interleukin-23 production

determination method or standard

1 reference

9 May 2019

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

lipopolysaccharide-mediated signaling pathway

determination method or standard

1 reference

9 May 2019

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

signal transduction

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

regulation of chemokine (C-X-C motif) ligand 2 production

determination method or standard

1 reference

9 May 2019

MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

regulation of interleukin-6 production

determination method or standard

1 reference

9 May 2019

MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

defense response to Gram-positive bacterium

determination method or standard

MyD88-dependent toll-like receptor signaling pathway

determination method or standard

4 references

9 May 2019

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Dectin-1 mediates the biological effects of beta-glucans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method or standard

3 references

9 May 2019

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

apoptotic process

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

cytokine-mediated signaling pathway

determination method or standard

1 reference

9 May 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22366

determination method or standard

positive regulation of smooth muscle cell proliferation

determination method or standard

1 reference

9 May 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22366

determination method or standard

Toll signaling pathway

determination method or standard

1 reference

9 May 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22366

determination method or standard

positive regulation of NF-kappaB transcription factor activity

determination method or standard

6 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

determination method or standard

1 reference

9 May 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22366

determination method or standard

type I interferon signaling pathway

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

positive regulation of interleukin-8 production

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

defense response to bacterium

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

cellular response to oxidised low-density lipoprotein particle stimulus

determination method or standard

1 reference

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

determination method or standard

1 reference

8 April 2019

The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

Toll signaling pathway

determination method or standard

3 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

defense response to Gram-positive bacterium

determination method or standard

3 references

9 May 2019

MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22366

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22366

Toll/interleukin-1 receptor homology (TIR) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22366

MyD88, death domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22366

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000035092

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000035092

ENSMUSP00000115746

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000115746

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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