Further developments on the cfd flow analysis inside the volumatic® spacer

• Autores: R. Rebelo, R. Oliveira, Luis F. Silva, S. Teixeira, José M. Cardoso Teixeira, H. Antunes
• Localización: Selected Proceedings from the 13th International Congress on Project Engineering: Badajoz, July 2009, 2010, ISBN 978-84-614-0185-7, págs. 443-451
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • In recent years, allergic diseases, particularly asthma, have been acquiring an increasing importance in the developed countries, due to the rising of its prevalence and morbidity and the economic burden associated. In the preventive and urgent treatment of asthma, the oral pharmacological therapeutics assumes a major role.

    Therefore, this paper will report another step further to the research been undertaken at the University of Minho, to understand the behaviour of drug flow inside a spacer device, combined with pressurized metered-dose inhalers (or pMDIs), based on the use of Computational Fluid Dynamics (CFD) tools to study multiphase flows inside a Volumatic® spacer device.

    This paper will present the two respiratory cycles used in the simulations. It will also report the analysis of the obtained results with the Volumatic® spacer using two different grid types (T-Grid and Cooper). With the obtained conclusions, it will be identified some new geometry possibilities for spacer devices (in terms of valve and body). Future work will be addressed to the study of these spacer geometry modifications.