Resumen de SEOM clinical guidelines for anaplastic gliomas (2017)
Carmen Balaña Quintero, M. Alonso Gil, A. Hernández Laín, Pedro Pérez Segura, Estela Pineda, Ana Ramos González, Ángel Rodríguez Sánchez, P. Teixidor, Eugènia Verger, Manuel Benavides Orgaz
The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 missense mutations and 1p/19q codeletions in AG. The diagnosis of anaplastic oligoastrocytoma is discouraged. Surgery, radiotherapy and chemotherapy with PCV or TMZ are the first-line standard of care for AG with slight modifications according to molecular variables. A multidisciplinary team is highly recommended in the management of these tumors.