Abstract:
Bone is one of the most implanted tissues worldwide. Bone tissue engineering deals with the replacement and regeneration of bone tissue; outcomes are determined by comple...Show MoreMetadata
Abstract:
Bone is one of the most implanted tissues worldwide. Bone tissue engineering deals with the replacement and regeneration of bone tissue; outcomes are determined by complex biological interactions, making it difficult to design an optimal tissue growth environment. Agent-Based Modeling (ABM) is a powerful tool to simulate such a system. We present a simulation of engineered bone tissue growth using the Repast HPC toolkit, an ABM tool for high-performance computing environments. We use this example to provide preliminary performance tests on new features (not yet publicly released) of Repast HPC that accommodate operations common to biological modeling: 3-Dimensional parallelized spatial simulation and diffusion in 3 dimensions. Repast HPC is a general ABM toolkit, and the performance documented here should be representative of performance on other simulations. Using the baseline Repast HPC tools provides flexibility for continued model development and improvement.
Published in: 2016 Winter Simulation Conference (WSC)
Date of Conference: 11-14 December 2016
Date Added to IEEE Xplore: 19 January 2017
ISBN Information:
Electronic ISSN: 1558-4305