Talk:Variants of SARS-CoV-2

Variants of SARS-CoV-2 was a Natural sciences good articles nominee, but did not meet the good article criteria at the time. There may be suggestions below for improving the article. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake.

Article milestones
Date	Process	Result
March 20, 2022	Good article nominee	Not listed

Molecular Biology: Genetics Low‑importance

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COVID-19 High‑importance

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Medicine: Emergency / Society / Pulmonology Low‑importance

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Viruses Mid‑importance

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Variants of SARS-CoV-2.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

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WikiProject COVID-19 consensus

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General

Superseded by TfD October 2020 and later practice - consult regular {{Current}} guidance.

Refrain from using Worldometer (worldometers.info) as a source due to common errors being observed as noted on the Case Count Task Force common errors page. (April 2020, April 2020)

For infoboxes on the main articles of countries, use Wuhan, Hubei, China for the origin parameter. (March 2020)

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Page title

COVID-19 (full caps) is preferable in the body of all articles, and in the title of all articles/category pages/etc.(RM April 2020, including the main article itself, RM March 2021).

SARS-CoV-2 (exact capitalisation and punctuation) is the common name of the virus and should be used for the main article's title, as well as in the body of all articles, and in the title of all other articles/category pages/etc. (June 2022, overturning April 2020)

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Section sizes

Section size for Variants of SARS-CoV-2 (68 sections)
Section name	Byte count	Section total
(Top)	2,980	2,980
Overview	7,111	7,111
Definitions	5,343	5,343
Notability criteria	3,215	3,215
Nomenclature	11,064	16,715
Lineages and clades	5,651	5,651
Reference sequence	5,327	5,327
Overview of historical variants of concern or under monitoring	20,513	20,513
Previously circulating and formerly monitored variants (WHO)	474	69,536
Previously circulating variants of concern (VOC)	299	46,555
Alpha (lineage B.1.1.7)	10,913	14,253
B.1.1.7 with E484K	3,340	3,340
Beta (lineage B.1.351)	6,343	6,343
Gamma (lineage P.1)	13,230	13,230
Delta (lineage B.1.617.2)	12,430	12,430
Previously circulating variants of interest (VOI)	1,055	20,877
Epsilon (lineages B.1.429, B.1.427, CAL.20C)	10,334	10,334
Zeta (lineage P.2)	113	113
Eta (lineage B.1.525)	4,359	4,359
Theta (lineage P.3)	4,585	4,585
Iota (lineage B.1.526)	175	175
Kappa (lineage B.1.617.1)	89	89
Lambda (lineage C.37)	86	86
Mu (lineage B.1.621)	81	81
Formerly monitored variants (WHO)	1,630	1,630
Omicron	117	15,279
Lineage B.1.1.529	4,119	4,119
BA. sublineages	2,016	2,016
XBB sublineages	2,306	2,306
Lineage BA.2.86	4,247	4,247
Sublineages by year	136	2,474
2024	2,338	2,338
Omicron variants under monitoring (WHO, 2022/2023)	2,295	2,295
Other notable variants	15,175	15,175
Recombinant variants	1,524	1,524
Incubation theory for multiple mutated variants	2,023	2,023
Notable missense mutations	109	38,550
del 69-70	708	708
RSYLTPGD246-253N	2,409	2,409
N440K	1,929	1,929
G446V	1,168	1,168
L452R	780	780
Y453F	765	765
S477G/N	2,469	2,469
E484Q	1,278	1,278
E484K	5,806	5,806
F490S	1,443	1,443
N501Y	2,624	2,624
N501S	1,687	1,687
D614G	5,847	5,847
Q677P/H	2,209	2,209
P681H	2,062	2,062
P681R	505	505
A701V	4,752	4,752
Data and methods	2,319	8,960
New variant detection and assessment	3,960	3,960
Testing	2,681	2,681
Cross-species transmission	2,089	6,390
Cluster 5	4,301	4,301
Vaccines	253	2,756
Differential vaccine effectiveness	2,324	2,503
Immune evasion by variants	91	91
Vaccine adjustments	88	88
See also	394	394
Notes	517	517
References	4,173	4,173
Further reading	1,026	1,026
External links	440	440
Total	230,242	230,242

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Refactoring notes

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A rather messy situation, given that these articles are not mainly edited by Wikipedia power-users. I've done a lot of refactoring on these articles, so here are my notes. In short, with the help of {{excerpt}}:

Where a variant is notable enough to have a substantial Wikipedia article, it will not be transcluded.
Where a variant is not notable enough to have a Wikipedia article substantially different from the section in Variants of SARS-CoV-2, it will be transcluded.
Every variant will link to Variants of SARS-CoV-2 via {{main}}.
No new articles on specific SARS-CoV-2 variants will be made, given the lack of notability, unless someone wants to create SARS-CoV-2 variants by year to condense all the inevitable new variants that will arise, which, as of 10 September 2024^[update], is currently in Variants of SARS-CoV-2#Sublineages by year.

This just leaves Omicron, which is rather unusual in that it is still, as of 10 September 2024^[update], the current "Variant of Concern". Since most people seem to be focusing on updating Variants of SARS-CoV-2 with new VOIs or VUMs, rather than SARS-CoV-2 Omicron variant, I've decided to transclude Variants of SARS-CoV-2's content into SARS-CoV-2 Omicron variant.

Then there's the section on vaccines. Currently, SARS-CoV-2 Omicron variant has more info on vaccines, so it has been transcluded to Variants of SARS-CoV-2. However, COVID-19 vaccine should be where that info goes. Unfortunately, it doesn't seem to be well updated, and has had sections transcluded from SARS-CoV-2 Omicron variant, which appears to be better updated with vaccine info.

So that's the situation right now. I don't know if the casual editors realize how much of this is a mess, but I hope this can serve as a guide as to where you need to edit:

Probably variants of SARS-CoV-2#Sublineages by year for 2025 and beyond, or COVID-19 vaccine, which needs a lot of work.⸺(Random)staplers 21:22, 10 September 2024 (UTC)[reply]

Nucleocapsid mutations, spike protein mutations

Wikipedia articles now talk only about mutation of spike protein.

What about major mutations in nucleocapsid? If sars2 spike mutations have now reached evoluationary dead end, it doesn't mean nucleocapsid mutations have.

Brief history of spike protein mutations, correct me if I'm wrong:

2021. Omicron has >50 mutations compared to Wuhan-2019 variant. Early subvariants BA.1 . . . BA.5.

2023. JN.1 has >30 mutations compared to first omicron cases.

2024. KP.3 is a subvariant of KP.2. KP.2 is a subvariant of JN.1

So only 2 major changes in spike protein, in 2021 and in 2023.

91.159.190.165 (talk) 15:03, 26 September 2024 (UTC)[reply]

thank you for posting--Ozzie10aaaa (talk) 23:43, 26 September 2024 (UTC)[reply]