Ovarian tumors, or ovarian neoplasms, are tumors arising from the ovary. They can be benign or malignant (ovarian cancer). They consists of mainly solid tissue, while ovarian cysts contain fluid.
Histopathologic classification
Ovarian tumors are classified according to the histology of the tumor, obtained in a pathology report. Histology dictates many aspects of clinical treatment, management, and prognosis.
The most common forms are:
| Type | Subtype | Relative incidence[2] | Percent malignant[2] | Comments | |
|---|---|---|---|---|---|
| Germ cell tumor | Mature cystic teratoma | 46,0% | 0,0% | ||
| Immature teratoma | 2,5% | 100,0% | |||
| Other germ cell tumors | 3,0% | Others mainly include dysgerminoma, yolk sac tumor, struma ovarii and squamous cell carcinoma arising from a dermoid cyst, and malignant mixed germ cell tumor.[2] | |||
| Surface epithelial-stromal tumor | Serous tumor | 25,3% | 18,5% | ||
| Mucinous tumor | 15,7% | 8,8% | |||
| Endometrioid tumor | 1,1% | 100,0% | |||
| Other surface-epithelial tumors | 1,4% | Others include mainly malignant mixed mullerian tumor, Brenner tumor and mixed epithelial tumor.[2] | |||
| Sex cord-stromal tumor | Fibroma | 1,4% | 0,0% | ||
| Adult granulosa cell tumor | 1,1% | 100,0% | |||
| Other sex cord-stromal tumors | 0,8% | Others include mainly juvenile granulosa cell tumor, thecoma and sclerosing stromal tumor[2] | |||
| Secondary/metastatic) tumor | 1,7% | 100,0% | Usually from breast cancer, colon cancer, endometrial cancer, stomach cancer or cervical cancer.[3] | ||
Mixed tumors contain elements of more than one of the above classes of tumor histology.
References
- ^ - Vaidya, SA; Kc, S; Sharma, P; Vaidya, S (2014). "Spectrum of ovarian tumors in a referral hospital in Nepal". Journal of Pathology of Nepal. 4 (7): 539–543. doi:10.3126/jpn.v4i7.10295. ISSN 2091-0908.
- Minor adjustment for mature cystic teratomas (0.17 to 2% risk of ovarian cancer): Mandal, Shramana; Badhe, Bhawana A. (2012). "Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A Case Report". Case Reports in Pathology. 2012: 1–3. doi:10.1155/2012/568062. ISSN 2090-6781.{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ a b c d e Unless otherwise specified in boxes, reference is: Vaidya, SA; Kc, S; Sharma, P; Vaidya, S (2014). "Spectrum of ovarian tumors in a referral hospital in Nepal". Journal of Pathology of Nepal. 4 (7): 539–543. doi:10.3126/jpn.v4i7.10295. ISSN 2091-0908.
- ^ Lisa Lee-Jones, University of Wales College of Medicine (2003-12-01). "Ovarian tumours : an overview". Atlas of Genetics and Cytogenetics in Oncology and Haematology.