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Effect of Nucleic Acid Amplification Testing on Population-Based Incidence Rates of Clostridium difficile Infection
- Gould, Carolyn V;
- Edwards, Jonathan R;
- Cohen, Jessica;
- Bamberg, Wendy M;
- Clark, Leigh Ann;
- Farley, Monica M;
- Johnston, Helen;
- Nadle, Joelle;
- Winston, Lisa;
- Gerding, Dale N;
- McDonald, L Clifford;
- Lessa, Fernanda C;
- Beldavs, Zintars;
- Hanna, Samir;
- Hollick, Gary;
- Holzbauer, Stacy;
- Lyons, Carol;
- Phipps, Erin;
- Wilson, Lucy
- et al.
Published Web Location
https://doi.org/10.1093/cid/cit492Abstract
Nucleic acid amplification testing (NAAT) is increasingly being adopted for diagnosis of Clostridium difficile infection (CDI). Data from 3 states conducting population-based CDI surveillance showed increases ranging from 43% to 67% in CDI incidence attributable to changing from toxin enzyme immunoassays to NAAT. CDI surveillance requires adjustment for testing methods.
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