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296 stars written in C++
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tools for working with genome variation graphs

C++ 1,256 210 Updated Nov 14, 2025

Open Babel is a chemical toolbox designed to speak the many languages of chemical data.

C++ 1,244 449 Updated Mar 4, 2025

Accelerated BLAST compatible local sequence aligner.

C++ 1,204 185 Updated Nov 10, 2025

Implementation of the Jupyter kernel protocol in C++

C++ 947 90 Updated Oct 27, 2025

gesture recognition toolkit

C++ 880 285 Updated Nov 1, 2019

SPAdes Genome Assembler

C++ 877 155 Updated Nov 10, 2025

Bayesian haplotype-based genetic polymorphism discovery and genotyping.

C++ 852 267 Updated May 31, 2025

🐟 🍣 🍱 Highly-accurate & wicked fast transcript-level quantification from RNA-seq reads using selective alignment

C++ 847 175 Updated May 29, 2024

The second version of the Kraken taxonomic sequence classification system

C++ 845 293 Updated Nov 7, 2025

A completely emoji-based programming language

C++ 817 54 Updated Oct 2, 2020

Versioned fork of the OpenCV gem for Ruby

C++ 813 128 Updated Apr 12, 2021

Python and C++ code for reading and writing genomics data.

C++ 795 122 Updated Dec 9, 2021
C++ 780 27 Updated Mar 11, 2018

Breakout Detection via Robust E-Statistics

C++ 761 180 Updated Aug 15, 2017

Oxford Nanopore's Basecaller

C++ 751 100 Updated Oct 21, 2025

A fast and sensitive gapped read aligner

C++ 751 170 Updated Sep 5, 2025

Read excel files (.xls and .xlsx) into R 🖇

C++ 746 199 Updated Sep 19, 2025

Versatile open-source tool for microbiome analysis

C++ 724 129 Updated Nov 8, 2025

A high-performance, Pythonic language for bioinformatics

C++ 704 49 Updated Dec 8, 2022

Hifiasm: a haplotype-resolved assembler for accurate Hifi reads

C++ 698 102 Updated Mar 18, 2025

A single molecule sequence assembler for genomes large and small.

C++ 695 179 Updated Nov 13, 2025

Procedural Hydrology / River / Lake Simulation

C++ 683 51 Updated Mar 20, 2023

Ultra-fast and memory-efficient (meta-)genome assembler

C++ 672 139 Updated Oct 28, 2025

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings

C++ 660 225 Updated Oct 31, 2025

a Bioinformatics Application for Navigating De novo Assembly Graphs Easily

C++ 654 108 Updated Dec 3, 2022

A pathtracer for R. Build and render complex scenes and 3D data visualizations directly from R

C++ 636 44 Updated Oct 20, 2025

High Performance Minecraft Map Renderer.

C++ 635 158 Updated Apr 25, 2024

hybrid assembly pipeline for bacterial genomes

C++ 625 137 Updated Jul 25, 2024

Signal-level algorithms for MinION data

C++ 589 161 Updated Aug 5, 2023

Lightweight, super fast C/C++ (& Python) library for sequence alignment using edit (Levenshtein) distance.

C++ 570 173 Updated May 13, 2025