- Middle sister of Jack Osbourne and Aimee Osbourne.
- Was hospitalized after fainting on the set of Fashion Police (2002) on March 7, 2013.
- Dropped out of the 10th grade.
- Younger half-sister of Louis Osbourne and Jessica Osbourne.
- Is friends with singer/songwriter Michelle Branch and Amy Winehouse.
- Dropped by her record label, Epic (2003)
- Her mentor is the late Joan Rivers.
- Filming Life as We Know It (2004), where she plays "Deborah Tynan", it will air this fall on ABC. (July 2004)
- Debut performance of her cover of Madonna's "Papa Don't Preach" at the 2002 MTV Movie Awards. (June 2002)
- Daughter of Ozzy Osbourne and Sharon Osbourne
- Was among the guests at Carmen Electra's and Dave Navarro's wedding
- Has haphophobia, [the fear of being touched].
- She loves to collect paintings of old movie stars, in particular, Marilyn Monroe.
- Her friend, singer Amy Winehouse, died on July 23, 2011, at age 27.
- A close friend of Lindsay Lohan.
- Grandaughter of Don Arden.
- Knew Joan Rivers when Osbourne was only 6 years old, she later worked with her on Fashion Police (2002).
- Ex-girlfriend of Bert McCracken, lead singer of rock band, The Used.
- Engaged to Matthew Mosshart [July 30, 2013].
- Has known Robert Pattinson since she was 18.
- Good friends with Kate Moss, and Jeannie Mai.
- On July 5, 2025, Osbourne announced her engagement to her longtime partner Slipknot DJ Sid Wilson. After nearly three years of dating.
- Along with Nicole Richie, Beyoncé, Veronica Webb, Angie Everhart, Alexandra Richards, Irina Pantaeva, Marisa Miller, Wyclef Jean, Rachel Hunter, Naomi Campbell, and Janice Dickinson, she participated in the "Fashion for Relief" show on 16 September, 2005 in New York, a benefit for AmeriCares to support victims for Hurricane Katrina. Gwen Stefani and Gavin Rossdale were among the celebrities who attended.
- Niece of David Arden
- Engaged to Matthew Mosshart (summer 2013).
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