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Lorenzo's Oil

  • 1992
  • PG-13
  • 2h 9m
IMDb RATING
7.3/10
25K
YOUR RATING
Susan Sarandon, Nick Nolte, and Zack O'Malley Greenburg in Lorenzo's Oil (1992)
DocudramaMedical DramaBiographyDrama

Lorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the p... Read allLorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the problem themselves.Lorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the problem themselves.

  • Director
    • George Miller
  • Writers
    • George Miller
    • Nick Enright
  • Stars
    • Nick Nolte
    • Susan Sarandon
    • Peter Ustinov
  • See production info at IMDbPro
  • IMDb RATING
    7.3/10
    25K
    YOUR RATING
    • Director
      • George Miller
    • Writers
      • George Miller
      • Nick Enright
    • Stars
      • Nick Nolte
      • Susan Sarandon
      • Peter Ustinov
    • 90User reviews
    • 37Critic reviews
    • 80Metascore
  • See production info at IMDbPro
  • See production info at IMDbPro
    • Nominated for 2 Oscars
      • 8 nominations total

    Photos107

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    Top cast96

    Edit
    Nick Nolte
    Nick Nolte
    • Augusto Odone
    Susan Sarandon
    Susan Sarandon
    • Michaela Odone
    Peter Ustinov
    Peter Ustinov
    • Professor Nikolais
    Kathleen Wilhoite
    Kathleen Wilhoite
    • Deirdre Murphy
    Gerry Bamman
    Gerry Bamman
    • Doctor Judalon
    Margo Martindale
    Margo Martindale
    • Wendy Gimble
    James Rebhorn
    James Rebhorn
    • Ellard Muscatine
    Ann Hearn
    Ann Hearn
    • Loretta Muscatine
    Maduka Steady
    Maduka Steady
    • Omouri
    Mary Wakio
    • Comorian Teacher
    Don Suddaby
    • Don Suddaby
    Colin Ward
    • Jake Gimble
    LaTanya Richardson Jackson
    LaTanya Richardson Jackson
    • Nurse Ruth
    • (as La Tanya Richardson)
    Jennifer Dundas
    Jennifer Dundas
    • Nurse Nancy Jo
    William Cameron
    William Cameron
    • Pellerman
    Becky Ann Baker
    Becky Ann Baker
    • Pellerman's Secretary
    Mary Pat Gleason
    Mary Pat Gleason
    • The Librarian
    David Shiner
    • Clown
    • Director
      • George Miller
    • Writers
      • George Miller
      • Nick Enright
    • All cast & crew
    • Production, box office & more at IMDbPro

    User reviews90

    7.325.1K
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    Featured reviews

    RachelLone

    Turning misfortune into miracles; turning tragedy into triumph

    This is the true story of Lorenzo Michael Murphy Odone, who, at the age of seven, suffered from a rare, incurable brain disease called ALD. The doctors said there was nothing they could do and that he would die within 24 months of diagnosis. Lorenzo's parents, Augusto Odone (Nick Nolte) and Michaela Odone (Susan Sarandon) decided to gather all the information they could find on their own. Day by day, night by night, from laymen to dedicated researchers, they discovered an awful lot more about the disorder than doctors and scientists. As Lorenzo's condition deteriorated, they never ceased to soldier on. Eventually, Augusto Odone solved the mystery and invented a prescription- a special form of olive oil which could help boys (the disease is passed on by the mothers to their sons, not their daughters) with ALD. Because of his contribution, Odone received an honorary medical degree. And at the age of fourteen, Lorenzo could make some movements and began trying to communicate with the outside world with a computer...

    I wept several times when watching this film. Notwithstanding all the odds, the Odones struggled and conquered their misfortune, and their achievement was outstanding. This is an intense drama with fine acting and something to think about deeply.
    8SnoopyStyle

    great sick-kid-drama

    Lorenzo Odone is a regular kid who spent three years in east Africa. Back in the States, he starts having disturbances. It's a mystery that his parents (Nick Nolte, Susan Sarandon) have difficulty solving until he is diagnosed as suffering from ALD. It's a rare incurable degenerative brain disorder that wasn't even identified 10 years before. There are no treatments and he's not expected to survive past 2 years. Then his parents goes all out to research his disease.

    This is a perfectly constructed sick-kid-drama. It excels because of the great performances. There is some science but the exposition is simple. And it's impossible not to like the old English scientist with 6 months before retirement. It is heart warming and a tear jerking. It is a great triumph of doggedness and parental love movie.
    kimnil80

    Really,really great!

    Wow!,what a film.Based on a true story about little boy Lorenzo who gets an incurable disease called ALG.Parents never gives up to get a cure for the disease.And a cure there is,in form of an oil.This is an heartwarming,interesting and very important movie.Great performances all around.Especially Nick Nolte who did a great job with his italian accent.Definately one of his best performances. Sarandon and Ustinov are also great.Not to mention the little boy who played Lorenzo,fantastic. However this movie is not so well known.For us who have seen it,we all agree this is one outstanding movie,that sticks to your mind for a long time...

    Rating 8/10
    gldie

    Gripping and moving drama

    "Lorenzo's Oil" is a movie about the triumph of human spirit and dogged determination. This movie is based on the true story of Michaela and Agusto Odone, whose child Lorenzo was diagnosed with adrenoleukodystrophy (ALD), a degenerative nerve disorder that afflicts only little boys and is always fatal. Michaela and Agusto are determined to find a cure or treatment for this baffling disease while their son slowly and painfully deteriorates. That is the basic premise for the movie, but it is about much more than that.

    Michaela and Agusto love their son with unwavering selflessness, and are willing to do anything in their power to save him. This movie is a gripping, touching drama that pulls you in and engulfs you, as finding a cure engulfs the Odones. By the end of the film you will feel a mix of emotions. This movie will give you a newfound respect for the mental and emotional power humans possess.
    george.schmidt

    Heartbreaking tale of the triumph of the human spirit; Sarandon's best work ever

    LORENZO'S OIL (1992) **** Nick Nolte, Susan Sarandon, Peter Ustinov, Zack O' Malley Greenburg, Kathleen Wilhoite. Powerful and educational true life story of Augusto and Michaela Odone who learn their young son is stricken with a devestating and rare disease (adrenoleukodystrophy or ALD) with no cure. The parents take on the awesome task of finding hope when doctors and support groups won't make an effort in learning how to conquer their son's debilitating nerve disorder. Although there are some distrubingly realistic depictions of a child suffering, the film never insults or preaches, but instead, enlightens. Sarandon, in my opinion was cheated out of an Oscar (she lost to Emma Thompson for "Howard's End"), gives the performance of her career and Nolte is wonderful as the frustrated father who risks everything in his research odyssey. Effectively directed by George Miller ("Mad Max") who also has a degree as a doctor (!)

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    Related interests

    Jesse Eisenberg in The Social Network (2010)
    Docudrama
    Patrick Dempsey and Ellen Pompeo in Grey's Anatomy (2005)
    Medical Drama
    Ben Kingsley, Rohini Hattangadi, and Geraldine James in Gandhi (1982)
    Biography
    Mahershala Ali and Alex R. Hibbert in Moonlight (2016)
    Drama

    Storyline

    Edit

    Did you know

    Edit
    • Trivia
      Don Suddaby (himself) is the actual British biochemist that has synthesized the pure oil (erucic acid) that was used to treat Lorenzo. He was born in Kingston upon Hull, England, where he has a street named after him, "Suddaby Close", which runs adjacent to "Lorenzo Way".
    • Quotes

      Augusto Odone: Michaela! They are the same enzyme! There is one enzyme for both chains. It's the same bloody enzyme!

    • Crazy credits
      During the credits pictures of children are shown, which were cured by "Lorenzo's Oil".
    • Connections
      Featured in Siskel & Ebert: Forever Young/Damage/Toys/Scent of a Woman/Used People (1992)
    • Soundtracks
      Kijana Mwana Mwali
      Written by Idylio Cortini and Roberto Marini

      Performed by Gonda Traditional Entertainers

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    FAQ19

    • How long is Lorenzo's Oil?Powered by Alexa

    Details

    Edit
    • Release date
      • January 29, 1993 (United States)
    • Countries of origin
      • United States
      • Australia
    • Languages
      • English
      • Italian
      • Swahili
    • Also known as
      • Un milagro para Lorenzo
    • Filming locations
      • Carnegie Mellon University - 5000 Forbes Avenue, Pittsburgh, Pennsylvania, USA(university scenes)
    • Production companies
      • Universal Pictures
      • Kennedy Miller Productions
    • See more company credits at IMDbPro

    Box office

    Edit
    • Budget
      • $30,000,000 (estimated)
    • Gross US & Canada
      • $7,286,388
    • Opening weekend US & Canada
      • $79,353
      • Jan 3, 1993
    • Gross worldwide
      • $7,286,388
    See detailed box office info on IMDbPro

    Tech specs

    Edit
    • Runtime
      • 2h 9m(129 min)
    • Color
      • Color
    • Sound mix
      • Dolby Stereo
    • Aspect ratio
      • 1.85 : 1

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