A young American woman is sent to Rome to begin a life of service to the church, but encounters a darkness that causes her to question her faith and uncovers a terrifying conspiracy that hopes to bring about the birth of evil incarnate.
A family heads to an isolated hotel for the winter, where a sinister presence influences the father into violence. At the same time, his psychic son sees horrifying forebodings from both the past and the future.
Five medical students, obsessed by what lies beyond the confines of life, embark on a daring experiment: by stopping their hearts for short periods, each triggers a near-death experience - giving them a firsthand account of the afterlife.