My Next Guest Needs No Introduction with David Letterman - Production & Contact Info

Cast	+ Add Cast
106 cast members

Name	Episodes	Known for
David Letterman Self - Host Self - Host See fewer	26	Late Show with David Letterman (1993)
Jerry Seinfeld Self - Host / Self - Seinfeld Co-Star Self - Host / Self - Seinfeld Co-Star See fewer	2	Seinfeld (1989)
Kim Kardashian Self Self See fewer	2	Disaster Movie (2008)
Clint Eastwood Self Self See fewer	1	Million Dollar Baby (2004)
Robin Williams Self (archive footage) Self (archive footage) See fewer	1	Mrs. Doubtfire (1993)
Zach Galifianakis Self Self See fewer	1	The Hangover (2009)
Shah Rukh Khan Self Self See fewer	1	Don 2 (2011)
Carol Burnett Self (archive footage) Self (archive footage) See fewer	1	The Carol Burnett Show (1967)
Portia de Rossi Self (archive footage) Self (archive footage) See fewer	1	Arrested Development (2003)
Richard Pryor Self (archive footage) Self (archive footage) See fewer	1	Superman III (1983)
Jay Leno Self (archive footage) Self (archive footage) See fewer	1	The Tonight Show with Jay Leno (1992)
Paul Mooney Self (archive footage) Self (archive footage) See fewer	1	Bamboozled (2000)
Bill Gates Self Self See fewer	1	Frasier (1993)
Robert Downey Jr. Self Self See fewer	1	Iron Man (I) (2008)
Dave Chappelle Self Self See fewer	1	Chappelle's Show (2003)
Lizzo Self Self See fewer	1	Lizzo: About Damn Time (2022)
Morgan Fallon Self Self See fewer	1	Anthony Bourdain: Parts Unknown (2013)
Martin Short Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	Innerspace (1987)
Blake Lively Self Self See fewer	1	Gossip Girl (2007)
Eddie Murphy Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	Harlem Nights (1989)
Christopher Guest Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	This Is Spinal Tap (1984)
Billy Crystal Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	Forget Paris (1995)
Mary Tyler Moore Self - Actress, The Mary Tyler Moore Show (archive footage) Self - Actress, The Mary Tyler Moore Show (archive footage) See fewer	1	Ordinary People (1980)
Spencer Tracy Self - Actor, Old Man and the Sea (archive footage) Self - Actor, Old Man and the Sea (archive footage) See fewer	1	Guess Who's Coming to Dinner (1967)
Carroll O'Connor Self - Actor, All in the Family (archive footage) Self - Actor, All in the Family (archive footage) See fewer	1	All in the Family (1971)
Julie London Self - Singer (archive footage) Self - Singer (archive footage) See fewer	1	Emergency! (1972)
Mary Gross Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	Saturday Night Live (1975)
Joe Piscopo Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	Saturday Night Live (1975)
Maggie Baird Self - Billie's Mother Self - Billie's Mother See fewer	1	Life Inside Out (2013)
Patrick O'Connell Self - Billie's Father Self - Billie's Father See fewer	1	Iron Man (I) (2008)
Tim Kazurinsky Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	Saturday Night Live (1975)
Robin Duke Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	Groundhog Day (1993)
Gary Kroeger Self - Saturday Night Live Co-Star (archive footage) Self - Saturday Night Live Co-Star (archive footage) See fewer	1	Saturday Night Live (1975)
Oleksandr Kamyshin Self Self See fewer	1	Global National (2001)
Anton Tymoshenko Self Self See fewer	1	Comedy of War: Laughter in Ukraine (2023)
Yulia Stefanyuk Self Self See fewer	1	My Next Guest Needs No Introduction with David Letterman (2018)
Jake Gyllenhaal Self - as Mr. Music (archive footage) Self - as Mr. Music (archive footage) See fewer	1	Nightcrawler (2014)
Chelsea Peretti Self - Stand Up Comedian (archive footage) Self - Stand Up Comedian (archive footage) See fewer	1	Parks and Recreation (2009)
Ali Wong Self - Stand Up Comedian (archive footage) Self - Stand Up Comedian (archive footage) See fewer	1	Ali Wong: Baby Cobra (2016)
Nate Bargatze Self - Stand Up Comedian (archive footage) Self - Stand Up Comedian (archive footage) See fewer	1	The Breadwinner (2026)
Hannibal Buress Self - Stand Up Comedian (archive footage) Self - Stand Up Comedian (archive footage) See fewer	1	Tag (I) (2018)
Billy Ray Cyrus Self - Miley's Father (archive footage) Self - Miley's Father (archive footage) See fewer	1	Hannah Montana: The Movie (2009)
Mike Birbiglia Self - Stand Up Comedian (archive footage) Self - Stand Up Comedian (archive footage) See fewer	1	A Man Called Otto (2022)
Jacqueline Novak Self - Stand Up Comedian (archive footage) Self - Stand Up Comedian (archive footage) See fewer	1	A Big Bold Beautiful Journey (2025)
Gayle King Self - Co-Host, King Charles (archive footage) Self - Co-Host, King Charles (archive footage) See fewer	1	The Manchurian Candidate (2004)
Reggie Miller Self - Former NBA Player (archive footage) Self - Former NBA Player (archive footage) See fewer	1	He Got Game (1998)
Nikki Haley Self - Republican Presidential Candidate (archive footage) Self - Republican Presidential Candidate (archive footage) See fewer	1	Army Wives (2007)
Diana Taurasi Self - Former Phoenix Mercury Player (archive footage) Self - Former Phoenix Mercury Player (archive footage) See fewer	1	Space Jam: A New Legacy (2021)
Aliyah Boston Self - Indiana Fever (archive footage) Self - Indiana Fever (archive footage) See fewer	1	ESPN College Basketball (1979)
Kelsey Mitchell Self - Indiana Fever (archive footage) Self - Indiana Fever (archive footage) See fewer	1
George Clooney Self Self See fewer	1	The Ides of March (2011)
Tina Fey Self Self See fewer	1	Date Night (2010)
Barack Obama Self Self See fewer	1	Leave the World Behind (2023)
Howard Stern Self Self See fewer	1	Howard Stern on Demand (2005)
Malala Yousafzai Self Self See fewer	1	Bread & Roses (2023)
Nate Holden Self Self See fewer	1	Basketball Wives (2010)
Tiffany Haddish Self Self See fewer	1	Girls Trip (2017)
Ellen DeGeneres Self Self See fewer	1	The Ellen DeGeneres Show (2003)
Ye Self (as Kanye West) Self (as Kanye West) See fewer	1	The Great Gatsby (2013)
Lewis Hamilton Self Self See fewer	1	Cars 2 (2011)
Melinda Gates Self Self See fewer	1	Origin (I) (2023)
Ryan Reynolds Self Self See fewer	1	Deadpool 2 (2018)
Will Smith Self Self See fewer	1	The Fresh Prince of Bel-Air (1990)
Julia Louis-Dreyfus Self Self See fewer	1	Seinfeld (1989)
Cardi B Self Self See fewer	1	Hustlers (2019)
Billie Eilish Self Self See fewer	1	No Time to Die (2021)
Volodymyr Zelenskyy Self - President of Ukraine Self - President of Ukraine See fewer	1	Svaty (2008)
Kevin Durant Self Self See fewer	1	Swagger (2021)
John Mulaney Self Self See fewer	1	Spider-Man: Into the Spider-Verse (2018)
Miley Cyrus Self Self See fewer	1	Hannah Montana (2006)
Charles Barkley Self - Inside The NBA Commentator Self - Inside The NBA Commentator See fewer	1	He Got Game (1998)
Caitlin Clark Self - Indiana Fever Self - Indiana Fever See fewer	1	ESPN College Basketball (1979)
Judd Apatow Self - Audience Member Self - Audience Member See fewer	1	Girls (2012)
Buddy Guy Self Self See fewer	1	Sinners (2025)
Nick Clooney Self - George's Father Self - George's Father See fewer	1	The Monuments Men (2014)
John Lewis Self Self See fewer	1	John Lewis: Good Trouble (2020)
Ziauddin Yousafzai Self - Malala's Father, Teacher & Activist Self - Malala's Father, Teacher & Activist See fewer	1	He Named Me Malala (2015)
Christa Sadler Self - Paleontologist Self - Paleontologist See fewer	1	The Colorado (2016)
Brad Hall Self - Julia's Husband (archive footage) Self - Julia's Husband (archive footage) See fewer	1	Brooklyn Bridge (1991)
Finneas O'Connell Self - Billie's Brother & Producer (as Finneas) Self - Billie's Brother & Producer (as Finneas) See fewer	1	No Time to Die (2021)
Tish Cyrus Self - Miley's Mother Self - Miley's Mother See fewer	1	LOL (2012)
Kenny Smith Self - Inside The NBA Commentator (as Kenny 'The Jet' Smith) Self - Inside The NBA Commentator (as Kenny 'The Jet' Smith) See fewer	1	Hustle (2022)
Charles Mulaney Self - John's Dad (as Chip) Self - John's Dad (as Chip) See fewer	1	My Next Guest Needs No Introduction with David Letterman (2018)
Lisa Bluder Self - Former lowa Hawkeyes Head Coach Self - Former lowa Hawkeyes Head Coach See fewer	1	Full Court Press (2024)
Jay-Z Self Self See fewer	1	The Harder They Fall (2021)
Nina Clooney Self - George's Mother Self - George's Mother See fewer	1	Screen Test (1979)
Charlie Hall Self - Julia's Son (archive footage) Self - Julia's Son (archive footage) See fewer	1	The Sex Lives of College Girls (2021)
Shaquille O'Neal Self - Inside The NBA Commentator Self - Inside The NBA Commentator See fewer	1	Steel (1997)
Carolyn Mulaney Self - John's Sister Self - John's Sister See fewer	1	My Next Guest Needs No Introduction with David Letterman (2018)
Rick Rubin Self Self See fewer	1	Battleship (2012)
Ada Clooney Self - George's Sister Self - George's Sister See fewer	1	My Next Guest Needs No Introduction with David Letterman (2018)
Henry Hall Self - Julia's Son (archive footage) Self - Julia's Son (archive footage) See fewer	1	Boo (2024)
Nick Kroll Self - Longtime Friend & Collaborator (archive footage) Self - Longtime Friend & Collaborator (archive footage) See fewer	1	Sausage Party (2016)
Ernie Johnson Self - Inside The NBA Commentator Self - Inside The NBA Commentator See fewer	1	Hustle (2022)
Madison Ryann Ward Self Self See fewer	1	Recorded Live at Analog Nashville (2024)
Hasim Avdal Self Self See fewer	1	My Next Guest Needs No Introduction with David Letterman (2018)
Gérard Louis-Dreyfus Self - Julia's Father (archive footage) Self - Julia's Father (archive footage) See fewer	1
Amal Clooney Self Self See fewer	1	Forced from Home
Judith Bowles Self - Julia's Mother (archive footage) Self - Julia's Mother (archive footage) See fewer	1
George Self - Julia's Dog Self - Julia's Dog See fewer	1	My Next Guest Needs No Introduction with David Letterman (2018)
Nathaniel K Wilson Self - Audience (uncredited) Self - Audience (uncredited) See fewer	2	Venom (2018)
Leslie Mann Self - Audience Member (uncredited) Self - Audience Member (uncredited) See fewer	1	Knocked Up (2007)
Iris Apatow Self - Audience Member (uncredited) Self - Audience Member (uncredited) See fewer	1	Funny People (2009)
Patrick Cotnoir Self - audience member (uncredited) Self - audience member (uncredited) See fewer	1	The George Lucas Talk Show (2020)
Lukas Nelson & Promise of the Real Themselves - Band in studio (uncredited) Themselves - Band in studio (uncredited) See fewer	1	Hitman's Wife's Bodyguard (2021)
Kris Jenner Self (uncredited) Self (uncredited) See fewer	1	The Mindy Project (2012)