Grey's Anatomy An Honest Mistake (Season 5, Episode 16)
TV-14
TV Episode | 60 min | Drama, Romance

Grey's Anatomy

An Honest Mistake (Season 5, Episode 16)

TV-14

TV Episode | 60 min | Drama, Romance

Addison and Derek differ on the treatment plan for their patient, Cristina discovers malpractice in high places, Izzie gets bad news, and Mark spectacularly mistimes his confession.

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Cast	+ Add Cast
25 cast members

Name	Known for
Ellen Pompeo Dr. Meredith Grey Dr. Meredith Grey See fewer	Grey's Anatomy (2005)
Sandra Oh Dr. Cristina Yang Dr. Cristina Yang See fewer	Killing Eve (2018)
Katherine Heigl Dr. Izzie Stevens Dr. Izzie Stevens See fewer	One for the Money (2012)
Justin Chambers Dr. Alex Karev Dr. Alex Karev See fewer	Grey's Anatomy (2005)
T.R. Knight Dr. George O'Malley Dr. George O'Malley See fewer	The Flight Attendant (2020)
Chandra Wilson Dr. Miranda Bailey Dr. Miranda Bailey See fewer	Grey's Anatomy (2005)
James Pickens Jr. Dr. Richard Webber Dr. Richard Webber See fewer	Grey's Anatomy (2005)
Sara Ramirez Dr. Callie Torres Dr. Callie Torres See fewer	Grey's Anatomy (2005)
Eric Dane Dr. Mark Sloan Dr. Mark Sloan See fewer	X-Men: The Last Stand (2006)
Chyler Leigh Dr. Lexie Grey Dr. Lexie Grey See fewer	Not Another Teen Movie (2001)
Kevin McKidd Dr. Owen Hunt Dr. Owen Hunt See fewer	Trainspotting (1996)
Patrick Dempsey Dr. Derek Shepherd Dr. Derek Shepherd See fewer	Grey's Anatomy (2005)
Kate Walsh Dr. Addison Montgomery Dr. Addison Montgomery See fewer	The Perks of Being a Wallflower (2012)
Jessica Capshaw Dr. Arizona Robbins Dr. Arizona Robbins See fewer	Valentine (2001)
Jennifer Westfeldt Jen Harmon Jen Harmon See fewer	Kissing Jessica Stein (2001)
Ben Shenkman Rob Harmon Rob Harmon See fewer	Pi (1998)
Kathleen Early Dr. Daisy Pepman Dr. Daisy Pepman See fewer	Across the Universe (2007)
Louis Giambalvo John Terzian John Terzian See fewer	Airplane II: The Sequel (1982)
Brandon Scott Dr. Ryan Spalding Dr. Ryan Spalding See fewer	Dead to Me (2019)
Faye Dunaway Dr. Margaret Campbell Dr. Margaret Campbell See fewer	Network (1976)
Susan Merson Lorraine Lorraine See fewer	Terminator 3: Rise of the Machines (2003)
Mark Saul Intern Steve Intern Steve See fewer	Grey's Anatomy (2005)
Gloria Garayua Intern Graciella Intern Graciella See fewer	Maid (2021)
Molly Kidder Intern Megan Intern Megan See fewer	Luckiest Girl Alive (2022)
Bokhee An Nurse Bokhee (uncredited) Nurse Bokhee (uncredited) See fewer	Grey's Anatomy (2005)