https://ruotian.io/tags/bio/ Recent content in Bio on Ruotian's I/O https://ruotian.io/apple-touch-icon.png https://ruotian.io/apple-touch-icon.png Hugo zh Fri, 08 Oct 2021 05:42:21 +0000 https://ruotian.io/2021/10/bwt/ Fri, 08 Oct 2021 05:42:21 +0000 https://ruotian.io/2021/10/bwt/ <figure> <img loading="lazy" src="https://ruotian.io/img/bwt.webp"/> </figure> <p>BWT: Burrows-Wheeler transform (aka. 块排序压缩)。</p> <h2 id="一篇-genome-biology-2009-的论文">一篇 Genome Biology 2009 的论文</h2> <p><a rel="noreferrer noopener" href="https://genomebiology.biomedcentral.com/articles/10.1186/gb-2009-10-3-r25" data-type="URL" data-id="https://genomebiology.biomedcentral.com/articles/10.1186/gb-2009-10-3-r25" target="_blank">《Ultrafast and memory-efficient alignment of short DNA sequences to the human genome》(Bowtie)</a></p> <p>这篇文章使用BWT对人类基因组建立索引，并用贪心+回溯支持模糊匹配。</p> https://ruotian.io/2020/02/2019-ncov/ Thu, 27 Feb 2020 17:43:28 +0800 https://ruotian.io/2020/02/2019-ncov/ <p>计算生物学课程的第一次作业。</p> <p><img alt="用不同种类冠状病毒生成的进化树" loading="lazy" src="https://ruotian.io/2020/02/2019-ncov/phylogenetic_tree.png"></p> <p><a href="./phylogenetic_tree.png">用不同种类冠状病毒生成的进化树</a></p> <p>红色的是2019-nCov，最接近的那个是个穿山甲体内的病毒。</p>