| Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites D Braig, TL Nero, HG Koch, B Kaiser, X Wang, JR Thiele, CJ Morton, ... Nature communications 8 (1), 14188, 2017 | 209 | 2017 |
| Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation LA Miles, GAN Crespi, L Doughty, MW Parker Scientific reports 3 (1), 1302, 2013 | 144 | 2013 |
| Cu2+ Binding Modes of Recombinant α-Synuclein − Insights from EPR Spectroscopy SC Drew, S Ling Leong, CLL Pham, DJ Tew, CL Masters, LA Miles, ... Journal of the American Chemical Society 130 (24), 7766-7773, 2008 | 124 | 2008 |
| Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies GAN Crespi, SJ Hermans, MW Parker, LA Miles Scientific reports 5 (1), 9649, 2015 | 108 | 2015 |
| Copper binding to the Alzheimer’s disease amyloid precursor protein GKW Kong, LA Miles, GAN Crespi, CJ Morton, HL Ng, KJ Barnham, ... European Biophysics Journal 37, 269-279, 2008 | 89 | 2008 |
| Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncated Abeta in sporadic Alzheimer disease cases … Y Bouter, JSL Noguerola, P Tucholla, GAN Crespi, MW Parker, J Wiltfang, ... Acta neuropathologica 130, 713-729, 2015 | 74 | 2015 |
| Do current therapeutic anti-Aβ antibodies for Alzheimer’s disease engage the target? AD Watt, GAN Crespi, RA Down, DB Ascher, A Gunn, KA Perez, ... Acta neuropathologica 127, 803-810, 2014 | 74 | 2014 |
| Small molecule binding to Alzheimer risk factor CD33 promotes Aβ phagocytosis LA Miles, SJ Hermans, GAN Crespi, JH Gooi, L Doughty, TL Nero, ... Iscience 19, 110-118, 2019 | 61 | 2019 |
| Amyloid-β–anti-amyloid-β complex structure reveals an extended conformation in the immunodominant B-cell epitope LA Miles, KS Wun, GAN Crespi, MT Fodero-Tavoletti, D Galatis, ... Journal of molecular biology 377 (1), 181-192, 2008 | 61 | 2008 |
| Synthetic dityrosine-linked β-amyloid dimers form stable, soluble, neurotoxic oligomers WM Kok, JM Cottam, GD Ciccotosto, LA Miles, JA Karas, DB Scanlon, ... Chemical Science 4 (12), 4449-4454, 2013 | 56 | 2013 |
| Genomics of Alzheimer’s disease implicates the innate and adaptive immune systems Y Li, SM Laws, LA Miles, JS Wiley, X Huang, CL Masters, BJ Gu Cellular and Molecular Life Sciences, 1-30, 2021 | 55 | 2021 |
| Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif LA Miles, CY Dy, J Nielsen, KJ Barnham, MG Hinds, BM Olivera, G Bulaj, ... Journal of Biological Chemistry 277 (45), 43033-43040, 2002 | 53 | 2002 |
| Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability KR Gillinder, MD Ilsley, D Nébor, R Sachidanandam, M Lajoie, GW Magor, ... Nucleic Acids Research 45 (3), 1130-1143, 2017 | 37 | 2017 |
| Structures of phage-display peptides that bind to the malarial surface protein, apical membrane antigen 1, and block erythrocyte invasion DW Keizer, LA Miles, F Li, M Nair, RF Anders, AM Coley, M Foley, ... Biochemistry 42 (33), 9915-9923, 2003 | 37 | 2003 |
| Rate constants for H+ (CH3) 4− nSiHn, n= 1–4 NL Arthur, LA Miles Chemical physics letters 282 (2), 192-196, 1998 | 35 | 1998 |
| Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid β peptide WM Kok, DB Scanlon, JA Karas, LA Miles, DJ Tew, MW Parker, ... Chemical Communications, 6228-6230, 2009 | 33 | 2009 |
| Arrhenius parameters for the reaction of H atoms with SiH 4 NL Arthur, LA Miles Journal of the Chemical Society, Faraday Transactions 93 (24), 4259-4264, 1997 | 33 | 1997 |
| Ex vivo 18O-labeling mass spectrometry identifies a peripheral amyloid β clearance pathway E Portelius, N Mattsson, J Pannee, H Zetterberg, M Gisslén, ... Molecular Neurodegeneration 12, 1-11, 2017 | 29 | 2017 |
| N‐terminal heterogeneity of parenchymal and vascular amyloid‐β deposits in Alzheimer’s disease S Zampar, HW Klafki, K Sritharen, TA Bayer, J Wiltfang, A Rostagno, ... Neuropathology and applied neurobiology 46 (7), 673-685, 2020 | 25 | 2020 |
| Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-β GAN Crespi, DB Ascher, MW Parker, LA Miles Acta Crystallographica Section F: Structural Biology Communications 70 (3 …, 2014 | 15 | 2014 |
