Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term ‘lncRNAs’ encompasses RNA polymerase I (Pol I), Pol II …

Background: Kawasaki disease is an acute vasculitis of childhood that leads to coronary
artery aneurysms in ≈25% of untreated cases. It has been reported worldwide and is the …

Childhood obesity is a global epidemic and rising trends in overweight and obesity are
apparent in both developed and developing countries. Available estimates for the period …

Sequencing of bacterial and archaeal genomes has revolutionized our understanding of the
many roles played by microorganisms 1 . There are now nearly 1,000 completed bacterial …

▪ Objective: To characterize mortality in persons diagnosed with primary pulmonary hypertension
and to investigate factors associated with survival. ▪ Design: Registry with prospective …

The recent discovery of superconductivity with relatively high transition temperature (Tc) in
the layered iron-based quaternary oxypnictides La[O 1−x F x ] FeAs by Kamihara et al. […

… × (1 + I/K i )], where V i is the inhibited velocity, V o is the initial velocity, S is the substrate (ATP)
concentration, K m is the Michaelis constant for ATP, I is the inhibitor (compound C) …

Objective. —To determine whether a program incorporating smoking intervention and use
of an inhaled bronchodilator can slow the rate of decline in forced expiratory volume in 1 …

Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500
million people and causes more than 1 million deaths each year. Tenfold shotgun sequence …

Tumour cells evade immune surveillance by upregulating the surface expression of programmed
death-ligand 1 (PD-L1), which interacts with programmed death-1 (PD-1) receptor on T …