In cell cultures of glial character derived from perinatal mouse brain adenosine elicits two
effects. (a) At submicromolar concentrations It inhibits the increase in the intracellular level of …

Postembryonic development of plants is dependent on both intrinsic genetic programs and
environmental factors. The plasticity of root hair patterning in response to environmental …

ADENOSINE stimulates the accumulation of cyclic AMP in some tissues and cell types, but
has inhibitory or biphasic effects on the accumulation of cyclic AMP in other cells. Londos and …

Hyperforin, a bicyclic polyprenylated acylphloroglucinol derivative, is the main active principle
of St. John's wort extract responsible for its anti‐depressive profile. Hyperforin inhibits the …

Purpose: To elicit a long-lasting antitumor immune response, CD8 + and CD4 + T cells should
be activated. We attempted to isolate HLA-DR–presented peptides directly from dissected …

MHC–peptide complexes mediate key functions in adaptive immunity. In a classical view,
MHC-I molecules present peptides from intracellular source proteins, whereas MHC-II …

Objective: To investigate the pharmacokinetic profile and tolerability of a single-dose infusion
of the new hydroxyethyl starch (HES) specification, HES (130/0.4), 6% and 10% solutions …

The major histocompatibility complex (MHC) presents peptides derived from degraded
cellular proteins to T-cells and is thus crucial for triggering specific immune responses against …

The protective epithelial barrier in our skin undergoes constant regulation, whereby the
balance between differentiation and proliferation of keratinocytes plays a major role. Impaired …

We develop a quantitative single cell-based mathematical model for multi-cellular tumor
spheroids (MCTS) of SK-MES-1 cells, a non-small cell lung cancer (NSCLC) cell line, growing …