Cardiovascular effects of 1 year of progressive and vigorous exercise training in previously sedentary individuals older than 65 years of age

N Fujimoto, A Prasad, JL Hastings, A Arbab-Zadeh… - Circulation, 2010 - ahajournals.org
Background— Healthy but sedentary aging leads to cardiovascular stiffening, whereas life-long
endurance training preserves left ventricular (LV) compliance. However, it is unknown …

Hemodynamic responses to rapid saline loading: the impact of age, sex, and heart failure

N Fujimoto, BA Borlaug, GD Lewis, JL Hastings… - Circulation, 2013 - ahajournals.org
Background— Hemodynamic assessment after volume challenge has been proposed as a
way to identify heart failure with preserved ejection fraction. However, the normal …

Native T1 mapping and extracellular volume mapping for the assessment of diffuse myocardial fibrosis in dilated cardiomyopathy

…, T Omori, I Goto, N Kumagai, N Fujimoto… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives : The purpose of this study was to examine the histological correlation of native
myocardial T1 and extracellular volume fraction (ECV) measurement at 3-T for the …

Effect of ageing on left ventricular compliance and distensibility in healthy sedentary humans

N Fujimoto, JL Hastings, PS Bhella… - The Journal of …, 2012 - Wiley Online Library
Key points • Healthy sedentary ageing leads to stiffening of the heart; however, when this
process occurs during ageing has been unknown. • In this study, 70 healthy sedentary subjects …

Impact of lifelong exercise “dose” on left ventricular compliance and distensibility

PS Bhella, JL Hastings, N Fujimoto, S Shibata… - Journal of the American …, 2014 - jacc.org
Background : Sedentary aging has deleterious effects on the cardiovascular system, including
decreased left ventricular compliance and distensibility (LVCD). Conversely, Masters level …

Cardiovascular effects of 1 year of progressive endurance exercise training in patients with heart failure with preserved ejection fraction

N Fujimoto, A Prasad, JL Hastings, PS Bhella… - American heart …, 2012 - Elsevier
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a disease of the
elderly with cardiovascular stiffening and reduced exercise capacity. Exercise training appears …

The effect of lifelong exercise dose on cardiovascular function during exercise

…, JL Hastings, PS Bhella, N Fujimoto… - Journal of applied …, 2014 - journals.physiology.org
An increased “dose” of endurance exercise training is associated with a greater maximal
oxygen uptake (V̇o 2max ), a larger left ventricular (LV) mass, and improved heart rate and …

Evaluation of the arrhythmogenecity of stress-induced “Takotsubo cardiomyopathy” from the time course of the 12-lead surface electrocardiogram

…, T Aoki, K Makino, C Omichi, N Fujimoto… - American Journal of …, 2003 - ajconline.org
Takotsubo cardiomyopathy (TC) is a rare syndrome with acute onset of ST-segment elevation,
subsequent giant negative T-wave inversion mimicking an acute coronary syndrome, and …

The effect of lifelong exercise frequency on arterial stiffness

S Shibata, N Fujimoto, JL Hastings… - The Journal of …, 2018 - Wiley Online Library
Key points This study examined the effect of different ‘doses’ of lifelong (>25 years) exercise
on arterial stiffening (a hallmark of vascular ageing) in older adults. There are clear dose‐…

High-temperature metal-organic vapor phase epitaxial growth of AlN on sapphire by multi transition growth mode method varying V/III ratio

M Imura, K Nakano, N Fujimoto, N Okada… - Japanese journal of …, 2006 - iopscience.iop.org
High-quality AlN layers were grown on c-plane sapphire substrates by high-temperature
metal-organic vapor phase epitaxy. AlN layers of about 9 µm in thickness with an atomically flat …