The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
N Yan, AD Regalado-Magdos, B Stiggelbout… - Nature …, 2010 - nature.com
Viral infection triggers innate immune sensors to produce type I interferon. However, infection
of T cells and macrophages with human immunodeficiency virus (HIV) does not trip those …
of T cells and macrophages with human immunodeficiency virus (HIV) does not trip those …
STING-associated vasculopathy develops independently of IRF3 in mice
Patients with stimulator of interferon genes (STING)–associated vasculopathy with onset in
infancy (SAVI) develop systemic inflammation characterized by vasculopathy, interstitial lung …
infancy (SAVI) develop systemic inflammation characterized by vasculopathy, interstitial lung …
Intrinsic antiviral immunity
Intrinsic antiviral immunity refers to a form of innate immunity that directly restricts viral replication
and assembly, thereby rendering a cell nonpermissive to a specific class or species of …
and assembly, thereby rendering a cell nonpermissive to a specific class or species of …
Co3O4 Nanocages for High-Performance Anode Material in Lithium-Ion Batteries
Co 3 O 4 nanoparticles have been prepared by a facile strategy, which involves the thermal
decomposition of nanoparticles of cobalt-based Prussian blue analogues at different …
decomposition of nanoparticles of cobalt-based Prussian blue analogues at different …
Identification of host proteins required for HIV infection through a functional genomic screen
AL Brass, DM Dykxhoorn, Y Benita, N Yan… - science, 2008 - science.org
HIV-1 exploits multiple host proteins during infection. We performed a large-scale small
interfering RNA screen to identify host factors required by HIV-1 and identified more than 250 HIV…
interfering RNA screen to identify host factors required by HIV-1 and identified more than 250 HIV…
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses
Retroviruses, including HIV, can activate innate immune responses, but the host sensors for
retroviruses are largely unknown. Here we show that HIV infection activates cyclic …
retroviruses are largely unknown. Here we show that HIV infection activates cyclic …
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to “seedless” 3′ UTR microRNA recognition elements
miR-24, upregulated during terminal differentiation of multiple lineages, inhibits cell-cycle
progression. Antagonizing miR-24 restores postmitotic cell proliferation and enhances …
progression. Antagonizing miR-24 restores postmitotic cell proliferation and enhances …
[HTML][HTML] Influence of salinity and water content on soil microorganisms
N Yan, P Marschner, W Cao, C Zuo, W Qin - International soil and water …, 2015 - Elsevier
Salinization is one of the most serious land degradation problems facing world. Salinity
results in poor plant growth and low soil microbial activity due to osmotic stress and toxic ions. …
results in poor plant growth and low soil microbial activity due to osmotic stress and toxic ions. …
STING activation by translocation from the ER is associated with infection and autoinflammatory disease
…, D Chen, VK Gonugunta, NM Alto, N Yan - Cell host & …, 2015 - cell.com
STING is an ER-associated membrane protein that is critical for innate immune sensing of
pathogens. STING-mediated activation of the IFN-I pathway through the TBK1/IRF3 signaling …
pathogens. STING-mediated activation of the IFN-I pathway through the TBK1/IRF3 signaling …
Hollow Porous SiO2 Nanocubes Towards High-performance Anodes for Lithium-ion Batteries
The high theoretical capacity and low discharge potential of silicon have attracted much
attention on Si-based anodes. Herein, hollow porous SiO 2 nanocubes have been prepared via …
attention on Si-based anodes. Herein, hollow porous SiO 2 nanocubes have been prepared via …