Genetically modified animal models are important for understanding the pathogenesis of
human disease and developing therapeutic strategies. Although genetically modified mice …

Huntington's disease (HD) is characterized by preferential loss of the medium spiny
neurons in the striatum. Using CRISPR/Cas9 and somatic nuclear transfer technology, we …

The domestic pig has been widely used as an important large animal model. Precise and
efficient genetic modification in pig provides a great promise in biomedical research. Recently, …

Embryonic stem (ES) cells are powerful tools for generating genetically modified animals
that can assist in advancing our knowledge of mammalian physiology and disease. Pigs …

The Siamese tracking framework has attracted much attention due to its scalability and efficiency
in recent years. However, it is less effective in recognizing arbitrary targets with various …

Gene targeting in mouse embryonic stem (ES) cells has revolutionized the field of mouse
genetics and allowed for the analysis of diverse aspects of gene function in vivo. For more than …

The feature models used by existing Thermal InfraRed (TIR) tracking methods are usually
learned from RGB images due to the lack of a large-scale TIR image training dataset. However…

Existing deep Thermal InfraRed (TIR) trackers only use semantic features to represent the
TIR object, which lack the sufficient discriminative capacity for handling distractors. This …

Dear Editor, Dogs (Canis familiaris) serve as human companions and are raised to herd
livestock, aid hunters, guard homes, perform police and rescue work, and guide the blind. Dogs …

Heterologous organ transplantation is an effective way of replacing organ function but is
limited by severe organ shortage. Although generating human organs in other large mammals …