Dynamic mapping of human cortical development during childhood through early adulthood

N Gogtay, JN Giedd, L Lusk… - Proceedings of the …, 2004 - National Acad Sciences
We report the dynamic anatomical sequence of human cortical gray matter development
between the age of 4–21 years using quantitative four-dimensional maps and time-lapse …

Mapping gray matter development: implications for typical development and vulnerability to psychopathology

N Gogtay, PM Thompson - Brain and cognition, 2010 - Elsevier
Recent studies with brain magnetic resonance imaging (MRI) have scanned large numbers
of children and adolescents repeatedly over time, as their brains develop, tracking …

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

…, L Sikich, T Stromberg, B Merriman, N Gogtay… - science, 2008 - science.org
Schizophrenia is a devastating neurodevelopmental disorder whose genetic influences remain
elusive. We hypothesize that individually rare structural variants contribute to the illness. …

Neurodevelopmental trajectories of the human cerebral cortex

…, K Eckstrand, R Lenroot, N Gogtay… - Journal of …, 2008 - Soc Neuroscience
… been found previously for the hippocampus (Gogtay et al., 2006). We were unable to measure
the hippocampus directly in the present study, but Gogtay and colleagues found that the …

Dynamic mapping of normal human hippocampal development

N Gogtay, TF Nugent III, DH Herman, A Ordonez… - …, 2006 - Wiley Online Library
The hippocampus, which plays an important role in memory functions and emotional responses,
has distinct subregions subserving different functions. Because the volume and shape …

Sexual dimorphism of brain developmental trajectories during childhood and adolescence

RK Lenroot, N Gogtay, DK Greenstein, EM Wells… - Neuroimage, 2007 - Elsevier
Human total brain size is consistently reported to be ∼8–10% larger in males, although
consensus on regionally specific differences is weak. Here, in the largest longitudinal pediatric …

How does your cortex grow?

…, D Greenstein, L Clasen, N Gogtay… - Journal of …, 2011 - Soc Neuroscience
Understanding human cortical maturation is a central goal for developmental neuroscience.
Significant advances toward this goal have come from two recent strands of in vivo structural …

Disrupted modularity and local connectivity of brain functional networks in childhood-onset schizophrenia

AF Alexander-Bloch, N Gogtay, D Meunier… - Frontiers in systems …, 2010 - frontiersin.org
Modularity is a fundamental concept in systems neuroscience, referring to the formation of
local cliques or modules of densely intra-connected nodes that are sparsely inter-connected …

Autism spectrum disorders and childhood-onset schizophrenia: clinical and biological contributions to a relation revisited

…, D Greenstein, A Addington, N Gogtay - Journal of the American …, 2009 - Elsevier
OBJECTIVE: To highlight emerging evidence for clinical and biological links between autism/pervasive
developmental disorder (PDD) and schizophrenia, with particular attention to …

Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia

PM Thompson, KM Hayashi, ER Sowell, N Gogtay… - Neuroimage, 2004 - Elsevier
This paper describes algorithms that can identify patterns of brain structure and function
associated with Alzheimer's disease, schizophrenia, normal aging, and abnormal brain …