Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green

A Peinnequin, C Mouret, O Birot, A Alonso, J Mathieu… - BMC immunology, 2004 - Springer
Background Cytokine mRNA quantification is widely used to investigate cytokine profiles,
particularly in small samples. Real-time polymerase chain reaction is currently the most …

Angiomotin regulates endothelial cell-cell junctions and cell motility

A Bratt, O Birot, I Sinha, N Veitonmäki, K Aase… - Journal of Biological …, 2005 - jbc.org
We have previously identified angiomotin by its ability to bind to and mediate the anti-angiogenic
properties of angiostatin. In vivo and in vitro data indicate an essential role of …

Angiomotin regulates endothelial cell migration during embryonic angiogenesis

…, L Jakobsson, A Majumdar, C Yi, O Birot… - Genes & …, 2007 - genesdev.cshlp.org
The development of the embryonic vascular system into a highly ordered network requires
precise control over the migration and branching of endothelial cells (ECs). We have …

Exercise‐induced expression of vascular endothelial growth factor mRNA in rat skeletal muscle is dependent on fibre type

OJG Birot, N Koulmann, A Peinnequin… - The Journal of …, 2003 - Wiley Online Library
In this study, we quantified the expression of the vascular endothelial growth factor (VEGF)
gene in individual muscle fibres at the end of a single 90 min run of 20−25 m min −1 , at 10 % …

Importance of anti‐angiogenic factors in the regulation of skeletal muscle angiogenesis

IM Olfert, O Birot - Microcirculation, 2011 - Wiley Online Library
Please cite this paper as: Olfert and Birot (2011). Importance of Anti‐angiogenic Factors in
the Regulation of Skeletal Muscle Angiogenesis. Microcirculation 18(4), 316–330. Abstract …

[HTML][HTML] Differential roles of p80-and p130-angiomotin in the switch between migration and stabilization of endothelial cells

M Ernkvist, O Birot, I Sinha, N Veitonmaki… - … et Biophysica Acta (BBA …, 2008 - Elsevier
We have previously shown that angiomotin (Amot) plays an important role in growth factor-induced
migration of endothelial cells in vitro. Genetic knock-down of Amot in zebrafish also …

Angio‐adaptation in unloaded skeletal muscle: new insights into an early and muscle type‐specific dynamic process

…, K Dehghan, D Desplanches, O Birot - The Journal of …, 2010 - Wiley Online Library
With a remarkable plasticity, skeletal muscle adapts to an altered functional demand.
Muscle angio‐adaptation can either involve the growth or the regression of capillaries as …

A DNA vaccine targeting angiomotin inhibits angiogenesis and suppresses tumor growth

L Holmgren, E Ambrosino, O Birot, C Tullus… - Proceedings of the …, 2006 - pnas.org
Endogenous angiogenesis inhibitors have shown promise in preclinical trials, but clinical
use has been hindered by low half-life in circulation and high production costs. Here, we …

Forkhead BoxO transcription factors restrain exercise‐induced angiogenesis

…, E Roudier, STK Liu, E Nwadozi, O Birot… - The Journal of …, 2014 - Wiley Online Library
Key points The growth of new capillaries, angiogenesis, within skeletal muscle occurs only
after weeks of repeated aerobic exercise. Paradoxically, large increases in pro‐angiogenic …

Blunted muscle angiogenic training-response in COPD patients versus sedentary controls

…, J Mercier, O Birot… - European …, 2013 - publications.ersnet.org
The impaired skeletal muscle of chronic obstructive pulmonary disease (COPD) patients
reduces exercise capacity. Similar to the oxidative muscle fibres, the angio-adaptation of …