Efficacy of rapid IV administration of valproic acid for status epilepticus
Although not approved by the US Food and Drug Administration for the treatment of status
epilepticus (SE), valproic acid (VPA) is an emerging option for this purpose. The authors …
epilepticus (SE), valproic acid (VPA) is an emerging option for this purpose. The authors …
The European genome-phenome archive in 2021
…, M Rueda, A Sankar, D Shaju, A Shimpi… - Nucleic Acids …, 2022 - academic.oup.com
The European Genome-phenome Archive (EGA - https://ega-archive.org/ ) is a resource for
long term secure archiving of all types of potentially identifiable genetic, phenotypic, and …
long term secure archiving of all types of potentially identifiable genetic, phenotypic, and …
Measuring and modelling tumour heterogeneity across scales
GF Beeghly, AA Shimpi, RN Riter… - Nature Reviews …, 2023 - nature.com
Cancer development, progression and therapy response are heterogeneous and patient-specific.
The biological and physical properties of tumour cells and their surrounding tissue …
The biological and physical properties of tumour cells and their surrounding tissue …
Collagen microarchitecture mechanically controls myofibroblast differentiation
Altered microarchitecture of collagen type I is a hallmark of wound healing and cancer that is
commonly attributed to myofibroblasts. However, it remains unknown which effect collagen …
commonly attributed to myofibroblasts. However, it remains unknown which effect collagen …
Engineered ECM models: Opportunities to advance understanding of tumor heterogeneity
AA Shimpi, C Fischbach - Current opinion in cell biology, 2021 - Elsevier
Intratumoral heterogeneity is a negative prognostic factor for cancer and commonly attributed
to microenvironment-driven genetic mutations and/or the emergence of cancer stem-like …
to microenvironment-driven genetic mutations and/or the emergence of cancer stem-like …
Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer
In patients with breast cancer, lower bone mineral density increases the risk of bone
metastasis. Although the relationship between bone-matrix mineralization and tumour-cell …
metastasis. Although the relationship between bone-matrix mineralization and tumour-cell …
[HTML][HTML] The learning curve for magnetic resonance imaging/ultrasound fusion-guided prostate biopsy
…, N Patel, E Cricco-Lizza, AA Shimpi… - European Urology …, 2019 - Elsevier
Background Magnetic resonance imaging/ultrasound-guided fusion biopsy (FBx) is more
accurate at detecting clinically significant prostate cancer than conventional transrectal …
accurate at detecting clinically significant prostate cancer than conventional transrectal …
An empirical explanation of the Cornsweet effect
D Purves, A Shimpi, RB Lotto - Journal of Neuroscience, 1999 - jneurosci.org
A long-standing puzzle in vision is the assignment of illusory brightness values to visual
territories based on the characteristics of their edges (the Craik–O’Brien–Cornsweet effect). …
territories based on the characteristics of their edges (the Craik–O’Brien–Cornsweet effect). …
Obesity‐Associated Adipose Stromal Cells Promote Breast Cancer Invasion through Direct Cell Contact and ECM Remodeling
Obesity increases the risk and worsens the prognosis for breast cancer due, in part, to
altered adipose stromal cell (ASC) behavior. Whether ASCs from obese individuals increase …
altered adipose stromal cell (ASC) behavior. Whether ASCs from obese individuals increase …
Suryanamaskar: An equivalent approach towards management of physical fitness in obese females
KA Jakhotia, AP Shimpi, SA Rairikar… - … Journal of Yoga, 2015 - journals.lww.com
Background: In India, obesity is highly prevalent in women as compared to men. As the obesity
epidemic spreads, there are growing concerns about efficient obesity management. Aims…
epidemic spreads, there are growing concerns about efficient obesity management. Aims…