User profiles for Ajay Pillai

Ajay Pillai

Cardiac Electrophysiologist, VCU Health
Verified email at vcuhealth.org
Cited by 161

Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India

…, ASN Seshasayee, M Bhat, Y Shouche, A Pillai… - Science, 2021 - science.org
Delhi, the national capital of India, experienced multiple severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) outbreaks in 2020 and reached population seropositivity of >50…

The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations

…, R Smith, K Devlin, R Margolis, L Derr, A Lee, A Pillai - Cell systems, 2018 - cell.com
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common
Fund program that catalogs how human cells globally respond to chemical, genetic, and …

Incidence of impacted third molars: A radiographic study in People's Hospital, Bhopal, India

AK Pillai, S Thomas, G Paul, SK Singh… - Journal of oral biology and …, 2014 - Elsevier
Objectives The aim of this study is to evaluate the position of impacted third molars based
on the classifications of Pell & Gregory and Winter in a sample of Bhopal patients. Study …

[HTML][HTML] Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop

…, A Bui, P Ping, NJ McKenna, R Madduri, A Pillai… - Journal of biomedical …, 2017 - Elsevier
The volume and diversity of data in biomedical research have been rapidly increasing in
recent years. While such data hold significant promise for accelerating discovery, their use …

[HTML][HTML] Malaria parasite clag3 genes determine channel-mediated nutrient uptake by infected red blood cells

W Nguitragool, AAB Bokhari, AD Pillai, K Rayavara… - Cell, 2011 - cell.com
Development of malaria parasites within vertebrate erythrocytes requires nutrient uptake at
the host cell membrane. The plasmodial surface anion channel (PSAC) mediates this …

Solute restriction reveals an essential role for clag3-associated channels in malaria parasite nutrient acquisition

AD Pillai, W Nguitragool, B Lyko, K Dolinta… - Molecular …, 2012 - Elsevier
The plasmodial surface anion channel (PSAC) increases erythrocyte permeability to many
solutes in malaria but has uncertain physiological significance. We used a PSAC inhibitor …

Atrioventricular junction ablation in patients with conduction system pacing leads: a comparison of His-bundle vs left bundle branch area pacing leads

A Pillai, J Kolominsky, JN Koneru, J Kron, RK Shepard… - Heart rhythm, 2022 - Elsevier
Background Single-center studies have shown feasibility of conduction system pacing (CSP)
via His-bundle pacing (HBP) or left bundle branch area pacing (LBBAP) in atrial fibrillation (…

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response …

…, M Medvedovic, A Ma'ayan, A Pillai… - Nucleic acids …, 2018 - academic.oup.com
The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national
consortium funded by the NIH to generate a diverse and extensive reference library of cell-…

Left bundle branch area pacing in patients with atrioventricular conduction disease: A prospective multicenter study

…, J Kolominsky, P Sanchez-Somonte, EE Gul, A Pillai… - Heart Rhythm, 2022 - Elsevier
Background The reported success rate of His-bundle pacing (HBP) in patients with infranodal
atrioventricular (AV) conduction disease is only 52%–76%. The success rate of left bundle …

Pharos 2023: an integrated resource for the understudied human proteome

…, J Holmes, KR Sharma, A Pillai… - Nucleic acids …, 2023 - academic.oup.com
The Illuminating the Druggable Genome (IDG) project aims to improve our understanding of
understudied proteins and our ability to study them in the context of disease biology by …