Human epidermal stem cells express higher levels of β1 integrins and are more adhesive
than keratinocytes that are destined to differentiate. To investigate whether high β1 integrin …

This paper introduces SpecInfer, a system that accelerates generative large language model
(LLM) serving with tree-based speculative inference and verification. The key idea behind …

Hedgehog (Hh) signaling is critical for many developmental events and must be restrained
to prevent cancer. A transmembrane protein, Smoothened (Smo), is necessary to …

We found that cultured human keratinocytes with high proliferative potential, the putative
epidermal stem cells, expressed a higher level of noncadherin-associated β- catenin than …

How developmental signaling proteins traverse tissue during animal development, through
or around tightly packed cells, remains an incompletely resolved mystery. Signaling protein …

Niemann-Pick type C (NPC) disease is a fatal autosomal-recessive neurodegenerative
disorder characterized by the inappropriate accumulation of unesterified cholesterol in aberrant …

Nonalcoholic fatty liver disease (NAFLD) is a global health concern with no approved drugs.
High-protein dietary intervention is currently the most effective treatment. However, its …

While current chat-based AI assistants primarily operate reactively, responding only when
prompted by users, there is significant potential for these systems to proactively assist in tasks …

Cell adhesion molecules are not only required for maintenance of tissue integrity, but also
regulate many aspects of cell behaviour, including growth and differentiation. While the …

Objectives : This study compared cardiac resynchronization therapy’s (CRT) impact on
ventricular tachyarrhythmia susceptibility in patients who, due to worsening heart failure (HF) …