Background Invasive candidosis is increasingly prevalent in seriously ill patients. Our aim
was to compare micafungin with liposomal amphotericin B for the treatment of adult patients …

Aims: To assess the concurrent and the construct validity of the Alcohol Use Disorders
Identification Test (AUDIT) in an urban Brazilian sample. Methods: A random sample of 166 …

To compare efficacy and safety of a tigecycline regimen with an imipenem/cilastatin regimen
in hospital-acquired pneumonia patients, a phase 3, multicenter, randomized, double-blind, …

FAP (familial amyloidotic polyneuropathy) is a systemic amyloid disease characterized by the
formation of extracellular deposits of transthyretin. More than 80 single point mutations are …

Background: Invasive candidiasis is increasingly prevalent in premature infants and seriously
ill children, and pediatric data on available antifungal therapies are lacking. Methods: We …

Background Vilobelimab, an anti-C5a monoclonal antibody, was shown to be safe in a
phase 2 trial of invasively mechanically ventilated patients with COVID-19. Here, we aimed to …

Objectives New therapies for complicated skin and skin structure infections (cSSSIs) are
needed because of significant morbidity and increasing antimicrobial resistance. Methicillin-…

The number of individuals affected by serious psychiatric disorders in Brazilian prisons is
unknown. This cross‐sectional study was conducted in prison complexes within the city of …

Background The greatest potential to reduce the burden of stroke is by primary prevention
of first-ever stroke, which constitutes three quarters of all stroke. In addition to population-wide …

Introduction: Focal cortical dysplasias (FCDs) are a group of malformations of cortical
development that constitute a common cause of drug-resistant epilepsy, often subjected to …