The brain produces two brain-derived neurotrophic factor (BDNF) transcripts, with either
short or long 3′ untranslated regions (3′ UTRs). The physiological significance of the two …

Expression of the brain-derived neurotrophic factor (BDNF) is under tight regulation to
accommodate its intricate roles in controlling brain function. Transcription of BDNF initiates from …

Elastic-viscoelastic correspondence was used to generate displacement–time solutions for
spherical indentation testing of soft biological materials with time-dependent mechanical …

One of the defining features of the nervous system is its ability to modify synaptic strength in
an experience-dependent manner. Chronic elevation or reduction of network activity …

The β 1 -adrenergic receptor (β 1 AR) is the most abundant subtype of β-adrenergic receptor
in the mammalian brain and is known to potently regulate synaptic plasticity. To search for …

β- and α 2 –adrenergic receptors are known to exhibit substantial cross-talk and mutual
regulation in tissues where they are expressed together. We have found that the β 1 -adrenergic …

Members of the transmembrane AMPA receptor-regulatory protein (TARP) family modulate
AMPA receptor (AMPA-R) trafficking and function. AMPA-Rs consist of four pore-forming …

Objective Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that is
elevated in the serum and synovial fluid of patients with osteoarthritis (OA). This study was …

The β 1 -adrenergic receptor (β 1 AR) is known to be localized to synapses and to modulate
synaptic plasticity in many brain regions, but the molecular mechanisms determining β 1 AR …

Chronic kidney disease (CKD) is a common disease of aging and increases fracture risk over
advanced age alone. Aging and CKD differently impair bone turnover and mineralization. …