Vancomycin's widespread use as the mainstay antibiotic against methicillin‐resistant
Staphylococcus aureus infections is complicated by its narrow therapeutic index. Therapeutic drug …

The recent SmartGraph platform facilitates the execution of complex drug-discovery workflows
with ease in the network-pharmacology paradigm. However, at the time of its publication …

Many structure/property relationships of hydrolyzed poly(ester urethane) (PEU) – a thermoplastic
– have been reported. Examples include changes in molecular weight vs. elongation at …

Production of blood-borne microparticles (MPs), 0.1–1 µm diameter vesicles, and interleukin
(IL)-1β in response to high pressure is reported in lab animals and associated with …

Rapid generation and evaluation of diverse synthesis pathways play a critical role in exploring
a broader chemical space and identifying potent drug candidates. Drug discovery often …

The hydrolysis of thermoplastic poly(ester urethane) (PEU) is convoluted by its block copolymer
phase structure and competing hydrolytic sensitivities of multiple functional groups. The …

The No Child Left Behind (NCLB) Act of 2001 requires states to ensure that all students make
adequate yearly progress in achieving proficiency in English language arts and math. This …

Flexible manufacturing systems operate in a dynamic environment and face considerable
uncertainty in production demands. The development of a flexible machine layout is a critical …

Purpose Crizotinib confers improved progression-free survival compared with chemotherapy
in anaplastic lymphoma kinase (ALK)-rearranged non–small-cell lung cancer (NSCLC), but …

Insulin-dependent diabetes mellitus (IDDM) is believed to be an autoimmune disease that
results from autoimmune destruction of the insulin-secreting β-cells of the pancreas. In …