The gut microbiota benefits humans via short-chain fatty acid (SCFA) production from
carbohydrate fermentation, and deficiency in SCFA production is associated with type 2 diabetes …

Calorie restriction has been regarded as the only experimental regimen that can effectively
lengthen lifespan in various animal models, but the actual mechanism remains controversial. …

Both genetic variations and diet-disrupted gut microbiota can predispose animals to metabolic
syndromes (MS). This study assessed the relative contributions of host genetics and diet …

The gut microbiota is hypothesized to have a critical role in metabolic diseases, including
type 2 diabetes (T2D). A traditional Chinese herbal formula, Gegen Qinlian Decoction (GQD), …

Butyrate-producing bacteria (BPB) are potential probiotic candidates for inflammatory bowel
diseases as they are often depleted in the diseased gut microbiota. However, here we found …

Inflammasomes are involved in gut homeostasis and inflammatory pathologies, but the role
of NLRP3 inflammasome in these processes is not well understood. Cryopyrin-associated …

Disruption of the gut microbiota by high-fat diet (HFD) has been implicated in the development
of obesity. It remains to be elucidated whether the HFD-induced shifts occur at the phylum …

Gut microbiota has been implicated as a pivotal contributing factor in diet-related obesity;
however, its role in development of disease phenotypes in human genetic obesity such as …

Structural disruption of gut microbiota and associated inflammation are considered
important etiological factors in high fat diet (HFD)-induced metabolic syndrome (MS). Three …

Berberine, a major pharmacological component of the Chinese herb Coptis chinensis,
which was originally used to treat bacterial diarrhea, has recently been demonstrated to be …