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Chien-Lun Chen

CGMH 長庚醫院
Подтвержден адрес электронной почты в домене cgmh.org.tw
Цитируется: 2105

Comparative and targeted proteomic analyses of urinary microparticles from bladder cancer and hernia patients

…, CW Hsu, CD Chen, YS Chang, PL Chang… - Journal of proteome …, 2012 - ACS Publications
Bladder cancer is a common urologic cancer whose incidence continues to rise annually.
Urinary microparticles are an attractive material for noninvasive bladder cancer biomarker …

[HTML][HTML] Identification of potential bladder cancer markers in urine by abundant-protein depletion coupled with quantitative proteomics

…, KY Chien, M Wu, YS Chang, JS Yu, YT Chen - Journal of …, 2013 - Elsevier
In this study, we evaluated the reproducibility of abundant urine protein depletion by
hexapeptide-based library beads and an antibody-based affinity column using the iTRAQ technique…

Development of a universal metabolome-standard method for long-term LC–MS metabolome profiling and its application for bladder cancer urine-metabolite …

J Peng, YT Chen, CL Chen, L Li - Analytical chemistry, 2014 - ACS Publications
Large-scale metabolomics study requires a quantitative method to generate metabolome
data over an extended period with high technical reproducibility. We report a universal …

Discovery of novel bladder cancer biomarkers by comparative urine proteomics using iTRAQ technology

…, MC Chen, KH Tsui, PL Chang, YS Chang… - Journal of proteome …, 2010 - ACS Publications
A urine sample preparation workflow for the iTRAQ (isobaric tag for relative and absolute
quantitation) technique was established. The reproducibility of this platform was evaluated and …

Multiplexed quantification of 63 proteins in human urine by multiple reaction monitoring-based mass spectrometry for discovery of potential bladder cancer biomarkers

…, CC Wu, CL Chen, T Chung, MC Chen, YS Chang… - Journal of …, 2012 - Elsevier
Three common urological diseases are bladder cancer, urinary tract infection, and hematuria.
Seventeen bladder cancer biomarkers were previously discovered using iTRAQ — these …

Multi-objective crowd-aware robot navigation system using deep reinforcement learning

CL Cheng, CC Hsu, S Saeedvand, JH Jo - Applied Soft Computing, 2024 - Elsevier
Navigating efficiently and safely through human crowds is essential for mobile robots in diverse
applications such as delivery services, home assistance, healthcare, and manufacturing. …

[HTML][HTML] Metabolite marker discovery for the detection of bladder cancer by comparative metabolomics

…, JY Lin, CJ Chen, SH Fu, YT Chen, YS Chang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Bladder cancer is one of the most common urinary tract carcinomas in the world. Urine
metabolomics is a promising approach for bladder cancer detection and marker discovery since …

Chronic Administration of Valproic Acid Inhibits Prostate Cancer Cell Growth In vitro and In vivo

Q Xia, J Sung, W Chowdhury, C Chen, N Höti… - Cancer Research, 2006 - AACR
Valproic acid (VPA) is an established drug in the long-term therapy of seizure disorders.
Recently, VPA has been associated with anticancer activity, an effect thought to be mediated …

Comparative tissue proteomics of microdissected specimens reveals novel candidate biomarkers of bladder cancer

…, CH Tsai, YS Chang, Y Liang, KH Tsui, YT Chen - Molecular & cellular …, 2015 - ASBMB
More than 380,000 new cases of bladder cancer are diagnosed worldwide, accounting for
∼150,200 deaths each year. To discover potential biomarkers of bladder cancer, we …

A sensitive and selective magnetic graphene composite-modified polycrystalline-silicon nanowire field-effect transistor for bladder cancer diagnosis

HC Chen, YT Chen, RY Tsai, MC Chen… - Biosensors and …, 2015 - Elsevier
In this study, we describe the urinary quantification of apolipoprotein A II protein (APOA2
protein), a biomarker for the diagnosis of bladder cancer, using an n-type polycrystalline silicon …