Because the protein's function is usually related to its subcellular localization, the ability to
predict subcellular localization directly from protein sequences will be useful for inferring …

The structure of a protein determines its function and its interactions with other factors.
Regions of proteins that interact with ligands, substrates, and/or other proteins, tend to be …

The structure of a protein determines its biological function(s) and its interactions with other
factors; the binding regions tend to be conserved in sequence and structure, and the …

Motivation MIB2 (metal ion-binding) attempts to overcome the limitation of structure-based
prediction approaches, with many proteins lacking a solved structure. MIB2 also offers more …

It has recently been shown that in proteins the atomic mean‐square displacement (or B‐factor)
can be related to the number of the neighboring atoms (or protein contact number), and …

CELLO2GO ( http://cello.life.nctu.edu.tw/cello2go/ ) is a publicly available, web-based system
for screening various properties of a targeted protein and its subcellular localization. Herein…

Integrin-mediated focal adhesions are the primary architectures that transmit forces between
the extracellular matrix (ECM) and the actin cytoskeleton. Although focal adhesions are …

Thrombospondin (TSP)-2, a matricellular glycoprotein of the TSP family, regulates multiple
biological functions, including proliferation, angiogenesis, cell adhesion, and extracellular …

Psoriasis is a chronic inflammatory skin disorder that affects ~2%–3% of the worldwide
population. Inappropriate and excessive activation of endosomal Toll‐like receptors 7, 8, and 9 (…

Macrophage accumulation and inflammation in the lung owing to stresses and diseases is a
cause of lung cancer development. However, molecular mechanisms underlying the …